LIPID AND LIPOPROTEIN ADSORPTION AT BIOMATERIALS AND BIO-DIAGNOSTICS INTERFACES. This project aims to investigate molecular mechanisms involved in the formation of undesired biological deposits on synthetic materials and thereby help establish the scientific basis for the rational design of materials with improved compatibility with biological fluids and the engineering of a new generation of biomedical implant devices and bio-diagnostic devices. It is well known that proteins accumulate on synt ....LIPID AND LIPOPROTEIN ADSORPTION AT BIOMATERIALS AND BIO-DIAGNOSTICS INTERFACES. This project aims to investigate molecular mechanisms involved in the formation of undesired biological deposits on synthetic materials and thereby help establish the scientific basis for the rational design of materials with improved compatibility with biological fluids and the engineering of a new generation of biomedical implant devices and bio-diagnostic devices. It is well known that proteins accumulate on synthetic solid surfaces. This project proposes to investigate whether lipids and lipoproteins also play key roles in the initiation of biological adsorption processes. Combined with the study of the interfacial forces responsible, this information will guide the design of preventative strategies.Read moreRead less
Modelling the capillary entrapment phenomena and integrity of geological reservoirs for clean energy, water and waste management technologies. This project will improve our understanding of non-linear flow and fracture phenomena in porous media which is prerequisite for the development of new emerging technologies targeting the reduction of the greenhouse gas emission and development of effective waste and water management solutions including coal gasification, in-situ storage of natural and non ....Modelling the capillary entrapment phenomena and integrity of geological reservoirs for clean energy, water and waste management technologies. This project will improve our understanding of non-linear flow and fracture phenomena in porous media which is prerequisite for the development of new emerging technologies targeting the reduction of the greenhouse gas emission and development of effective waste and water management solutions including coal gasification, in-situ storage of natural and non-hydrocarbon gases, underground disposal of hazardous wastes and vadose zone remediation. The project will result in a dramatic improvement of the predictive tools for traditional ground water management, irrigation and petroleum recovery applications. It has the strength to place Australia in the forefront of these technologies. Read moreRead less
Periodic nano-ratchets: a new paradigm for biomolecule separation. This project proposes the theoretical and experimental study of a new separation principle. The platform technologies developed from this research will see wide ranging applications. They will reveal new insights into fundamental phenomena of membranes and separation processes underpinning development of new generation of separation technologies. New membranes and microchip separation devices which can be applied to genomic, prot ....Periodic nano-ratchets: a new paradigm for biomolecule separation. This project proposes the theoretical and experimental study of a new separation principle. The platform technologies developed from this research will see wide ranging applications. They will reveal new insights into fundamental phenomena of membranes and separation processes underpinning development of new generation of separation technologies. New membranes and microchip separation devices which can be applied to genomic, proteomic, forensic and a range medical, biotechnological and analytical applications will be readily achievable. This is an international and interdisciplinary research project and its outcomes will enhance Australia's ability in frontier technologies, advanced materials.Read moreRead less