Field-Enhanced Electrospinning for Fine and Uniform Nanofibres. This project will result in a new platform technology to produce very fine and uniform nanofibres that can be used in a range of advanced applications. It will further strengthen our leading position in the field of nanofibre technology, and contribute to the National Research Priority area of Frontier Technologies for Building and Transforming Australian Industries. Australia already has niche expertise in nanomaterials. This proje ....Field-Enhanced Electrospinning for Fine and Uniform Nanofibres. This project will result in a new platform technology to produce very fine and uniform nanofibres that can be used in a range of advanced applications. It will further strengthen our leading position in the field of nanofibre technology, and contribute to the National Research Priority area of Frontier Technologies for Building and Transforming Australian Industries. Australia already has niche expertise in nanomaterials. This project will significantly enhance our international standing in the field. There is a growing list of local companies that are interested in exploring the production and application of nanofibrous materials also.Read moreRead less
The flotation of oxide minerals using hydroxamate collectors. Australian and world mineral resources are declining in quality as we exploit the richest sulfidic ore deposits. This is increasing our reliance on concentration and beneficiation processes to improve the economics of the selective recovery of minerals from lower grade and, increasingly, oxide or lateritic ore bodies. In addition, greater emphasis is being placed on our environmental stewardship and the need to remove hazardous mater ....The flotation of oxide minerals using hydroxamate collectors. Australian and world mineral resources are declining in quality as we exploit the richest sulfidic ore deposits. This is increasing our reliance on concentration and beneficiation processes to improve the economics of the selective recovery of minerals from lower grade and, increasingly, oxide or lateritic ore bodies. In addition, greater emphasis is being placed on our environmental stewardship and the need to remove hazardous material from the concentrate streams. This proposal will develop improved methods and techniques that will facilitate better, cleaner separations and recovery of the valuable oxide mineral components using Australian-developed flotation reagents.Read moreRead less
Chemistry of uranium extraction - studies on the dissolution of uranium ores in a complex solution matrix. Olympic Dam is the world's largest uranium deposit. With a planned massive expansion of the mine's operations, it could generate more than $10b per year. The mineral ores found there, however, are highly complex and poorly understood. This project will investigate and determine the detailed characteristics and chemistry of the mineral ore and offer process improvements that will increase th ....Chemistry of uranium extraction - studies on the dissolution of uranium ores in a complex solution matrix. Olympic Dam is the world's largest uranium deposit. With a planned massive expansion of the mine's operations, it could generate more than $10b per year. The mineral ores found there, however, are highly complex and poorly understood. This project will investigate and determine the detailed characteristics and chemistry of the mineral ore and offer process improvements that will increase the productivity and improve the economics of extraction of the ore. This project will also address the serious deficiency of researchers in this field by creating a sustainable skills development program in mineral extraction and separation technology.Read moreRead less
New Imaging Agents for Neuronal Nicotinic Receptors. Recent advances in medical imaging technology such as Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) have radically improved the diagnosis and treatment of a wide range of diseases. The aim of this project is to discover novel radio-ligands that selectively bind to neuronal nicotinic acetylcholine receptors. These ligands will have great potential for the imaging, diagnosis and study of neurodegenerat ....New Imaging Agents for Neuronal Nicotinic Receptors. Recent advances in medical imaging technology such as Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) have radically improved the diagnosis and treatment of a wide range of diseases. The aim of this project is to discover novel radio-ligands that selectively bind to neuronal nicotinic acetylcholine receptors. These ligands will have great potential for the imaging, diagnosis and study of neurodegenerative diseases such as Alzheimer's disease. Read moreRead less
Development of a neutral helium beam microscope. This project would demonstrate Australia's capability in developing leading edge technologies applicable to the growing nanotechnology industry. The development of a neutral helium beam microscope brings into Australia expertise in the emerging field of molecular optics, and would place Australia as one of the first countries to make a commitment to this field. The project will develop a prototype instrument which is aimed at becoming a commercial ....Development of a neutral helium beam microscope. This project would demonstrate Australia's capability in developing leading edge technologies applicable to the growing nanotechnology industry. The development of a neutral helium beam microscope brings into Australia expertise in the emerging field of molecular optics, and would place Australia as one of the first countries to make a commitment to this field. The project will develop a prototype instrument which is aimed at becoming a commercially viable product - the neutral helium beam microscope. The possibilities of using the microscope system as a nanofabrication device would also give researchers in Australia the ability to fabricate structures that could not be manufactured anywhere else in the world.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0453651
Funder
Australian Research Council
Funding Amount
$907,511.00
Summary
Small Molecule NMR Facility for Accelerated Drug Discovery. This project will accelerate the drug discovery process by establishing a world-class small-molecule Nuclear Magnetic Resonance (NMR) facility. The requested instrumentation will enable high throughput structural analysis of synthetic lead compounds, expedite natural product isolation and identification and enhance NMR-based drug screening. This facility will support both existing and new programs in Victorian universities, particularly ....Small Molecule NMR Facility for Accelerated Drug Discovery. This project will accelerate the drug discovery process by establishing a world-class small-molecule Nuclear Magnetic Resonance (NMR) facility. The requested instrumentation will enable high throughput structural analysis of synthetic lead compounds, expedite natural product isolation and identification and enhance NMR-based drug screening. This facility will support both existing and new programs in Victorian universities, particularly Medicinal and Biological Chemistry, and achieve internationally competitive research capabilities. Outcomes will include the development of new pharmaceuticals, increased local and international collaboration and the training of new scientists in state-of-the-art spectroscopic techniques for identification of natural products and synthetic molecules of pharmacological importance.
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Joint Theoretical and Experimental Electron Momentum Spectroscopic Studies for DNA Bases. The study of DNA structure is an area of intense research activity and continues to reveal new levels of complexity and diversity. Recent experiments (Science, 2002) provided direct evidences of the adenine non-planarity, indicating non-rigidity of DNA bases. Electron momentum spectroscopy (EMS) has been identified to be an appropriate technique in the study of chemical binding mechanism and orbitals at mol ....Joint Theoretical and Experimental Electron Momentum Spectroscopic Studies for DNA Bases. The study of DNA structure is an area of intense research activity and continues to reveal new levels of complexity and diversity. Recent experiments (Science, 2002) provided direct evidences of the adenine non-planarity, indicating non-rigidity of DNA bases. Electron momentum spectroscopy (EMS) has been identified to be an appropriate technique in the study of chemical binding mechanism and orbitals at molecular level. The aims of the project is to study orbitals and interactions of DNA and RNA bases such as adenine, thymine (uracil), guanine and cytosine using momentum space quantum mechanics and EMS experimental techniques. The outcome of the project will improve our understanding of the DNA double helical strand structure.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0346895
Funder
Australian Research Council
Funding Amount
$450,000.00
Summary
A Mass Directed Molecular Resolution Laboratory. The proposed "Mass Directed Molecular Resolution Laboratory" combines an integrated suite of instrumentation housed in purpose built laboratories with technical expertise to provide an unique "one stop shop" to meet the burgeoning mass spectrometry needs of the chemical community in the Melbourne area. This truly collaborative effort will service the needs of 17 research groups with 92 PhD students and post doctoral researchers and will enhance ex ....A Mass Directed Molecular Resolution Laboratory. The proposed "Mass Directed Molecular Resolution Laboratory" combines an integrated suite of instrumentation housed in purpose built laboratories with technical expertise to provide an unique "one stop shop" to meet the burgeoning mass spectrometry needs of the chemical community in the Melbourne area. This truly collaborative effort will service the needs of 17 research groups with 92 PhD students and post doctoral researchers and will enhance existing excellence in a range of areas. Finally, the laboratory will provide opportunities to: collaborate and consult with industry; train postgraduate students in instrumentation used at the cutting edge of chemical and biochemical sciences.Read moreRead less
Tailoring the optical properties of matter with Sol-Gel: innovative optical materials for 3D photonic crystals with complete photonic band-gap. The success of this project will allow for improvement of existing technologies in diverse fields, from optics to green energy production. Realization of 3D complete Photonic Band-Gap (PBG) structures is the first step toward full optic-based data processing systems, which will be one of the most revolutionary achievements in technology after introductio ....Tailoring the optical properties of matter with Sol-Gel: innovative optical materials for 3D photonic crystals with complete photonic band-gap. The success of this project will allow for improvement of existing technologies in diverse fields, from optics to green energy production. Realization of 3D complete Photonic Band-Gap (PBG) structures is the first step toward full optic-based data processing systems, which will be one of the most revolutionary achievements in technology after introduction of electronic-based processors. Improvement of energy conversion efficiency of existing solar cells and polymer-based solar cells will be achievable thanks to implementation of PhCs as high-reflective layers. The establishment of scaleable protocols for production of high quality materials for photonics will put Australia among the leading countries in the future photonic-devices market.Read moreRead less
Nanoporous bioaffinity adsorbents for separations in the pharmaceutical industry. This proposal aims to develop new high performance adsorbents for bioprocess engineering based on templated nanoporous silica materials. This research will lead to significant advances in advanced materials and adsorbent technology, downstream processing for the biotechnology industries, and understanding of highly specific affinity interactions used for difficult bioseparations. It will have important benefits for ....Nanoporous bioaffinity adsorbents for separations in the pharmaceutical industry. This proposal aims to develop new high performance adsorbents for bioprocess engineering based on templated nanoporous silica materials. This research will lead to significant advances in advanced materials and adsorbent technology, downstream processing for the biotechnology industries, and understanding of highly specific affinity interactions used for difficult bioseparations. It will have important benefits for processes involving protein purification, such as bioplasma processing, as well as flow on effects to other applications of adsorbent technology such as food processing and water treatment. The new adsorbents will lead to reductions in the costs, energy usage and waste generation of Australian industries.Read moreRead less