Plasma Activated Hydrogel Therapy For Combatting Antimicrobial Resistance In Chronic Wounds
Funder
National Health and Medical Research Council
Funding Amount
$755,023.00
Summary
The aim is to advance wound care using electrical ionised gas discharge (plasma) to deliver antimicrobial and healing agents through tailored hydrogel dressings into wounds. The technology will be configured for real-world wounds and clinical settings and its antimicrobial delivery system will be optimised to eradicate all wound pathogens and prevent re-infection. The technology has potential to revolutionise chronic wound care and alleviate the growing problem of antimicrobial resistance.
Efficacy Of Activated Protein C To Treat Diabetic Leg Ulcers - A Randomised, Controlled Clinical Trial
Funder
National Health and Medical Research Council
Funding Amount
$519,284.00
Summary
Chronic leg ulcers are a major public health burden. Research undertaken by the CIs and funded by a NHMRC Development Grant have shown that activated protein C heals chronic wounds in animals and now in humans, and resolved mechanisms underlying activated protein C's actions. The current chronic leg ulcer trial is an essential step to validate the therapeutic use of activated protein C in wound healing, which is likely to emerge as a cost-effective treatment for this difficult health problem.
Wounds are not just the simple cuts and abrasions that can be covered with a band-aid and healed within days with no major consequence. They are a largely unrecognised spiralling epidemic that is affecting millions of people world-wide. This project aims to develop new approaches to heal wounds with research that is innovative, cross-disciplinary and has the ability to transform current approaches for wound management.