Ink jet microfluidic spray drier for making high quality microencapsulated bioactive particles and nanosized particles. The proposal addresses National Research Priority area 3 (Frontier Technology). This work will develop a new, simple and effective method for producing designer smart particles that have better functional properties as well as improved uniformity for application in the food and pharmaceutical industries. The project will train graduates who will be able to make a high-level con ....Ink jet microfluidic spray drier for making high quality microencapsulated bioactive particles and nanosized particles. The proposal addresses National Research Priority area 3 (Frontier Technology). This work will develop a new, simple and effective method for producing designer smart particles that have better functional properties as well as improved uniformity for application in the food and pharmaceutical industries. The project will train graduates who will be able to make a high-level contribution to these Australian industries. This will also mark a development in Australia¡¯s nanotechnology capability in the bio-area.Read moreRead less
Engineering Nanostructured Bio-inspired Products. New nanostructured products that draw on biology promise to revolutionise our lives and economy. Designer emulsions and self-assembling particles inspired by viruses are two such products that form the focus for this research programme. The constitutive behaviour of bio-molecular films that control emulsion performance will be characterised and linked to molecular properties and manufacturing conditions. A broad-based technology platform for t ....Engineering Nanostructured Bio-inspired Products. New nanostructured products that draw on biology promise to revolutionise our lives and economy. Designer emulsions and self-assembling particles inspired by viruses are two such products that form the focus for this research programme. The constitutive behaviour of bio-molecular films that control emulsion performance will be characterised and linked to molecular properties and manufacturing conditions. A broad-based technology platform for the in vitro creation of self-assembling biological nanoparticles will also be developed. Key outcomes will be valuable IPR and fundamental engineering science knowledge to ensure that the value chain for this class of products can deliver commercial outcomes.Read moreRead less
New nanocomposites of porous materials and visible light sensitive TiO2 for efficient wastewater purification. The innovative newly proposed materials can trap and efficiently decompose dissolved organics in the same process, without generating any waste for disposal. No UV is required and the solar radiation can be efficiently used. The proposed research will be a significant breakthrough in the field of water treatment that reduces energy consumption, uses low cost materials and provides a rea ....New nanocomposites of porous materials and visible light sensitive TiO2 for efficient wastewater purification. The innovative newly proposed materials can trap and efficiently decompose dissolved organics in the same process, without generating any waste for disposal. No UV is required and the solar radiation can be efficiently used. The proposed research will be a significant breakthrough in the field of water treatment that reduces energy consumption, uses low cost materials and provides a real solution. The research findings will be useful to a wide spectrum of manufacturing industries which are currently generating slightly contaminated wastewater, and will be beneficial to the community in general. At the same time, the industries will be a step forward toward sustainable manufacturing.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE170100068
Funder
Australian Research Council
Funding Amount
$390,000.00
Summary
Bioinspired liposome-based smart sensors. This project aims to develop a liposome-based biosensor technology that mimics cell sensory systems. Selective detection of compounds is increasingly important for food, health and environmental monitoring. Biosensor development faces long-standing challenges such as response time, sensitivity, specificity, and multiplexing. On the other hand, cells can sense and discriminate multiple biomolecules in seconds with high sensitivity and specificity. This pr ....Bioinspired liposome-based smart sensors. This project aims to develop a liposome-based biosensor technology that mimics cell sensory systems. Selective detection of compounds is increasingly important for food, health and environmental monitoring. Biosensor development faces long-standing challenges such as response time, sensitivity, specificity, and multiplexing. On the other hand, cells can sense and discriminate multiple biomolecules in seconds with high sensitivity and specificity. This project aims to harness cells’ exquisite biological properties to improve current detection techniques. It will integrate liposome-based sensors with microfluidics to perform analytical tasks ranging from food safety to diagnostics.Read moreRead less
Forces in high salt concentrations: from mineral processing to proteins. The outcomes of this program will have significant contributions to the fundamental understanding of colloidal science, the study of particle suspensions. This project will help answer longstanding questions in the food, pharmaceutical and mining industries, two of which are primary industries for Australia. In these industries, innovative solutions can substantially improve productivity, increasing export potential and re ....Forces in high salt concentrations: from mineral processing to proteins. The outcomes of this program will have significant contributions to the fundamental understanding of colloidal science, the study of particle suspensions. This project will help answer longstanding questions in the food, pharmaceutical and mining industries, two of which are primary industries for Australia. In these industries, innovative solutions can substantially improve productivity, increasing export potential and reducing the environmental impact. The outcomes of this work, in the form of high impact papers and conference presentations, will continue to build and enhance Australia's international research reputation and in time engage industries to transfer and commercialization of the present fundamental study.Read moreRead less
Microfluidic Studies of Stimuli-Responsive Emulsions. Breakthrough 'stimuli-responsive interface technology' has been developed in Australia to allow better control over emulsions, which are oil-in-water mixtures used widely in everyday products such as medicines. This project will increase our understanding of this new technology, by examining how the chemistry of the molecules at the interface interacts with fluid behaviour when the emulsion is made. The research will employ miniature lab-on-a ....Microfluidic Studies of Stimuli-Responsive Emulsions. Breakthrough 'stimuli-responsive interface technology' has been developed in Australia to allow better control over emulsions, which are oil-in-water mixtures used widely in everyday products such as medicines. This project will increase our understanding of this new technology, by examining how the chemistry of the molecules at the interface interacts with fluid behaviour when the emulsion is made. The research will employ miniature lab-on-a-chip systems, to give engineers and scientists design rules for this new technology, opening the way to new products that will improve our everyday lives. One immediate product to be researched is 'precision' double emulsions, which show unique properties for the delivery of chemotherapy medicines.Read moreRead less
Metal Alkynyl Materials for Photonics. Investment in this project (i) will gain Australia entry into an international network of researchers investigating materials (particularly NLO) properties of organometallic and other compounds, (ii) will involve training four PhD students, who will graduate with highly developed interdisciplinary skills, (iii) may identify new materials with sufficient performance for commercial development, and (iv) will build bridges between traditional research in organ ....Metal Alkynyl Materials for Photonics. Investment in this project (i) will gain Australia entry into an international network of researchers investigating materials (particularly NLO) properties of organometallic and other compounds, (ii) will involve training four PhD students, who will graduate with highly developed interdisciplinary skills, (iii) may identify new materials with sufficient performance for commercial development, and (iv) will build bridges between traditional research in organometallic chemistry and that in nanophotonics and biophotonics, and position Australia as a major player in these nascent fields.Read moreRead less
Engineered nanostructured materials via continuous polymer assembly for advanced bioapplications. The development of new and flexible processes is critical to the design and construction of advanced materials for future applications in nano- and biotechnology. This project will develop innovative and versatile "bottom-up" nanotechnology techniques to afford nanostructured materials with unprecedented properties. This project has the potential to revolutionise current approaches for forming surfa ....Engineered nanostructured materials via continuous polymer assembly for advanced bioapplications. The development of new and flexible processes is critical to the design and construction of advanced materials for future applications in nano- and biotechnology. This project will develop innovative and versatile "bottom-up" nanotechnology techniques to afford nanostructured materials with unprecedented properties. This project has the potential to revolutionise current approaches for forming surface coatings, films and advanced particles, leading to significant outcomes in diverse areas, including drug delivery, biomaterial implants and biocatalysis. The project will contribute to the development of a robust Australian nanotechnology industry, with the advanced materials developed expected to have health benefits for Australian citizens.Read moreRead less
Building Molecularly Engineered Polymer Nanomaterials. The development of new technologies at the interface between nano- and biotechnology promises to revolutionise healthcare and medicine. This research program will involve the design and synthesis of responsive and programmable polymers and their assembly to form next-generation, engineered materials. The nanomaterials prepared are expected to lead to the development of techniques that enable new types of minimally invasive diagnostics and th ....Building Molecularly Engineered Polymer Nanomaterials. The development of new technologies at the interface between nano- and biotechnology promises to revolutionise healthcare and medicine. This research program will involve the design and synthesis of responsive and programmable polymers and their assembly to form next-generation, engineered materials. The nanomaterials prepared are expected to lead to the development of techniques that enable new types of minimally invasive diagnostics and therapeutics as well as smaller devices. The interdisciplinary research program will cement Australia's position as a leading country in nanobiotechnology research and development.Read moreRead less
Engineering and Assembly of Bioinspired Nanostructured Materials. Scientific and technological advances at the frontiers of nano- and bio-technology are poised to revolutionise healthcare and medicine. This project will involve the design, synthesis and engineering of functional biopolymer building blocks. These 'smart' biopolymers will then be assembled into responsive, nanostructured materials for targeted drug delivery and biosensing applications. These materials are expected to ultimately ha ....Engineering and Assembly of Bioinspired Nanostructured Materials. Scientific and technological advances at the frontiers of nano- and bio-technology are poised to revolutionise healthcare and medicine. This project will involve the design, synthesis and engineering of functional biopolymer building blocks. These 'smart' biopolymers will then be assembled into responsive, nanostructured materials for targeted drug delivery and biosensing applications. These materials are expected to ultimately have health benefits for Australian citizens and contribute to the development of a robust Australian nanobiotechnology industry. The project will also provide excellent opportunities for the development of outstanding young scientists and will foster exciting, multidisciplinary collaborations.Read moreRead less