Protein biosensors for detecting smoke exposure of grapes. Bush fires and controlled burns that take place in the vicinity of vineyards can lead to grape contamination with tasteless phenolic glucosides. Their hydrolysis during wine making leads to “smoke taint” – an unpleasant medicinal taste that can render wine undrinkable. We will apply a combination of organic synthesis, protein engineering and directed evolution to develop protein-based biosensors of phenolic glucosides. These biosensors w ....Protein biosensors for detecting smoke exposure of grapes. Bush fires and controlled burns that take place in the vicinity of vineyards can lead to grape contamination with tasteless phenolic glucosides. Their hydrolysis during wine making leads to “smoke taint” – an unpleasant medicinal taste that can render wine undrinkable. We will apply a combination of organic synthesis, protein engineering and directed evolution to develop protein-based biosensors of phenolic glucosides. These biosensors will be used to devise a simple portable colorimetric test that can be performed in the vineyard or the winery. The ability to rapidly determine the level of grape contamination with phenolic glucosides would give Australian wine growers and wine makers a powerful tool to mitigate the effects of bushfires.Read moreRead less
Next-generation ocean current forecasting to improve maritime safety . This project aims to measure upper ocean currents at scales of 10-100 km in Australia's marine estate using pioneering satellite radar technology. The Surface Water and Ocean Topography (SWOT) mission will map currents at 10 times the resolution of present-day satellites and revolutionise our understanding of ocean dynamics. Expected outcomes include validation of SWOT data in Australian waters and merging this data into Bure ....Next-generation ocean current forecasting to improve maritime safety . This project aims to measure upper ocean currents at scales of 10-100 km in Australia's marine estate using pioneering satellite radar technology. The Surface Water and Ocean Topography (SWOT) mission will map currents at 10 times the resolution of present-day satellites and revolutionise our understanding of ocean dynamics. Expected outcomes include validation of SWOT data in Australian waters and merging this data into Bureau of Meteorology ocean models. Downstream benefits include improved ocean forecasts for maritime safety, search-and-rescue, spill modelling, and marine conservation. At the same time, the project will build sovereign capability in emerging remote sensing technology with a legacy beyond the life of the SWOT mission.Read moreRead less
Preventing railway suicide: An open-systems perspective. Preventing railway suicide: An open-systems perspective. This project aims to develop an automated suicide risk detection system to reduce the incidence and impact of railway suicide, which has a devastating effect on victims’ families, station staff, train drivers, emergency workers, and bystanders. This project will use open-systems theory to develop two complementary information systems for more effective detection and reporting of suic ....Preventing railway suicide: An open-systems perspective. Preventing railway suicide: An open-systems perspective. This project aims to develop an automated suicide risk detection system to reduce the incidence and impact of railway suicide, which has a devastating effect on victims’ families, station staff, train drivers, emergency workers, and bystanders. This project will use open-systems theory to develop two complementary information systems for more effective detection and reporting of suicide risk; use these systems to investigate how different situational factors interact with different combinations of service interventions to influence suicide risk; and share the findings to reduce railway suicide in Australia and overseas.Read moreRead less
Microbiologically Induced Stress Corrosion Cracking in Underground Mines. Premature brittle failure of rock & cable bolts due to stress corrosion cracking can cause fatalities and serious damage, and has been reported in several mining operations across Australia and world-wide. The evidence suggests that microbial activity is a contributing factor. The project aims to implement experimental methodologies to determine the specific conditions responsible for bolt failure and develop novel prevent ....Microbiologically Induced Stress Corrosion Cracking in Underground Mines. Premature brittle failure of rock & cable bolts due to stress corrosion cracking can cause fatalities and serious damage, and has been reported in several mining operations across Australia and world-wide. The evidence suggests that microbial activity is a contributing factor. The project aims to implement experimental methodologies to determine the specific conditions responsible for bolt failure and develop novel prevention techniques applicable in underground mines. The benefits of this research will be improved understanding of the environment causing catastrophic failure of bolts and avoidance of potential hazards & economic loss in mining projects. This will lead to improved safety & increased productivity in mining operations.Read moreRead less
Gender equality in Australia: impact on social, economic and health outcomes. This project aims to develop an innovative, Australian-specific multidimensional measure of gender equality. The project’s focus on conceptualising and measuring gender equality in the Australian context will address a significant barrier to the development, implementation and evaluation of targeted gender equality programs and policies. By partnering with government and industry representatives, this project will deve ....Gender equality in Australia: impact on social, economic and health outcomes. This project aims to develop an innovative, Australian-specific multidimensional measure of gender equality. The project’s focus on conceptualising and measuring gender equality in the Australian context will address a significant barrier to the development, implementation and evaluation of targeted gender equality programs and policies. By partnering with government and industry representatives, this project will develop a baseline from which programs and policies can be measured. The project will also establish evidence about the effects of gender equality in relation to economic, social and wellbeing outcomes.Read moreRead less
Using multiple data sources to understand the opioid crisis in Australia . This project aims to improve the quality and integration of population-level data for monitoring the consumption of opioids, licit and illicit, in Queensland communities. The analysis of opioids in wastewater, integrated with opioid use information such as prescription and seizure statistics will vastly increase knowledge of consumption patterns of opioids. By analysing wastewater samples from 2011 and triangulating with ....Using multiple data sources to understand the opioid crisis in Australia . This project aims to improve the quality and integration of population-level data for monitoring the consumption of opioids, licit and illicit, in Queensland communities. The analysis of opioids in wastewater, integrated with opioid use information such as prescription and seizure statistics will vastly increase knowledge of consumption patterns of opioids. By analysing wastewater samples from 2011 and triangulating with other datasets, the expected outcomes include building capacity to estimate consumption of all opioids; detecting the misuse of licit and illicit opioids over time. Anticipated benefit is to provide objective evidence of opioid use patterns for decision makers and a framework for a national opioids monitoring program.Read moreRead less
Surveillance and sampling to maintain absence of pests and diseases. This project aims to develop empirically validated statistical and mathematical methods for industry and government to deliver more efficient biosecurity surveillance programs. The project endeavours to enhance biosecurity at the border and within Australia, while minimising the costs and burden of testing. Expected project outcomes include effective surveillance and sampling for high-priority threats, accessible software for d ....Surveillance and sampling to maintain absence of pests and diseases. This project aims to develop empirically validated statistical and mathematical methods for industry and government to deliver more efficient biosecurity surveillance programs. The project endeavours to enhance biosecurity at the border and within Australia, while minimising the costs and burden of testing. Expected project outcomes include effective surveillance and sampling for high-priority threats, accessible software for decision-makers, and generalisable approaches to address rapidly increasing biosecurity risks. Significant benefits include maintaining absence of key pathogens and pests in Australia.Read moreRead less
Integrated Planning for Uncertainty-Centric Pilot Assistance Systems. This project aims to deliver a novel pilot assistance system to improve the viability, speed and safety of Helicopter Emergency Medical Services (HEMS) and Search and Rescue (SAR) missions. It will advance fundamental algorithms for probabilistic planning in partially observable scenarios to form the core technology of a pilot assistance system that accounts the various types of uncertainty faced by pilots in a typical HEMS/S ....Integrated Planning for Uncertainty-Centric Pilot Assistance Systems. This project aims to deliver a novel pilot assistance system to improve the viability, speed and safety of Helicopter Emergency Medical Services (HEMS) and Search and Rescue (SAR) missions. It will advance fundamental algorithms for probabilistic planning in partially observable scenarios to form the core technology of a pilot assistance system that accounts the various types of uncertainty faced by pilots in a typical HEMS/SAR missions. It will exploit recent advances in Partially Observable Markov Decision Processes (POMDPs) to recommend robust, safe, and pilot-aware mission and manoeuvring strategies to make HEMS/SAR operations safer for helicopter crews, and more effective for those in need of the service.Read moreRead less
Towards in-vehicle situation awareness using visual and audio sensors. This project aims to characterise driver awareness, activity and interactions with other vehicle occupants using visual and audio cues from internally mounted sensors. Road accidents cost Australia an estimated $30 billion per year and tragic loss of thousands of lives, yet the vast majority of severe vehicle crashes are linked to driver fatigue or distraction. The expected project outcomes include advanced artificial intelli ....Towards in-vehicle situation awareness using visual and audio sensors. This project aims to characterise driver awareness, activity and interactions with other vehicle occupants using visual and audio cues from internally mounted sensors. Road accidents cost Australia an estimated $30 billion per year and tragic loss of thousands of lives, yet the vast majority of severe vehicle crashes are linked to driver fatigue or distraction. The expected project outcomes include advanced artificial intelligence to infer and predict dangerous driver and passenger behaviour. This has the potential to significantly benefit society by advancing autonomous driving capabilities and reducing driver-induced accidents and fatalities, ensuring that every driver, passenger and pedestrian arrives home safely at the end of each day.Read moreRead less