Molecular characterisation of antibiotic resistance genes in Salmonella enterica and Escherichia coli recovered from food-producing animals and humans. Antibiotic resistance is an accelerating global problem. Antibiotic resistance genes are located on mobile genetic elements which can be horizontally transferred between distantly related bacteria. It is becoming increasingly apparent that healthy humans carry populations of resistant bacteria as part of the normal microbial flora. This project w ....Molecular characterisation of antibiotic resistance genes in Salmonella enterica and Escherichia coli recovered from food-producing animals and humans. Antibiotic resistance is an accelerating global problem. Antibiotic resistance genes are located on mobile genetic elements which can be horizontally transferred between distantly related bacteria. It is becoming increasingly apparent that healthy humans carry populations of resistant bacteria as part of the normal microbial flora. This project will characterise the antibiotic resistance gene arrangements among populations of bacteria which belong to the Enterobacteriaceae. These resistant bacteria represent a threat to human and veterinary health because they are readily ingested as part of the food chain and represent reservoirs for the spread of antibiotic resistance genes to pathogens.Read moreRead less
Portable biosensor for rapid detection of viral contamination in food . The objective of this project is to create a miniaturised and cost-effective electrochemical biosensor device that can detect multiple pathogens, simultaneously, even at very low level of concentrations. This device will be crucial for rapidly detect pathogen contamination in food and water to monitor their safety and quality, particularly beneficial in an outbreak or natural disaster for testing these resources. In additio ....Portable biosensor for rapid detection of viral contamination in food . The objective of this project is to create a miniaturised and cost-effective electrochemical biosensor device that can detect multiple pathogens, simultaneously, even at very low level of concentrations. This device will be crucial for rapidly detect pathogen contamination in food and water to monitor their safety and quality, particularly beneficial in an outbreak or natural disaster for testing these resources. In addition to food and water, the successful development of this versatile cost-effective sensor will benefit a wide range of companies such as pharmaceuticals, medical device manufacturing and farms for controlling product quality where detection of life threatening pathogens is pivotal to prevent risk for consumers.Read moreRead less
Improved biosecurity through the engineering of microbial ecosystems. This project aims to provide data and understanding that will help develop predictive models for changes in the distribution of drug-resistant bacteria, and surveillance and response programs for key biosecurity threats. Microorganisms, including commensals and pathogens, can live in complex communities in a range of environments including animal hosts. It is now known that these communities (known as microbiomes) can exert a ....Improved biosecurity through the engineering of microbial ecosystems. This project aims to provide data and understanding that will help develop predictive models for changes in the distribution of drug-resistant bacteria, and surveillance and response programs for key biosecurity threats. Microorganisms, including commensals and pathogens, can live in complex communities in a range of environments including animal hosts. It is now known that these communities (known as microbiomes) can exert a profound effect on animal health. This project seeks to understand where antimicrobial resistance genes reside in pig gut microbiotia and how they move between members of this complex microbial community, and to provide information on how probiotics may be used to reduce dependence on antibiotics.Read moreRead less
Discovery and characterisation of novel lanthipeptide biopreservatives. The aim of this project is to advance fundamental knowledge of microbial metabolism and provide natural anti-microbial molecules to the Australian food industry. A quarter of the world’s food supply is lost because of microbiological spoilage. Some chemical preservatives have been developed to combat food spoilage organisms, however their chronic impact on human health is the subject of debate. Consumer demand for safe and n ....Discovery and characterisation of novel lanthipeptide biopreservatives. The aim of this project is to advance fundamental knowledge of microbial metabolism and provide natural anti-microbial molecules to the Australian food industry. A quarter of the world’s food supply is lost because of microbiological spoilage. Some chemical preservatives have been developed to combat food spoilage organisms, however their chronic impact on human health is the subject of debate. Consumer demand for safe and natural alternatives is growing. Paradoxically, microbially-produced bioactive peptides may be the key to combating food spoilage organisms and food-borne pathogens. To this end, the project intends to develop an innovative strategy for the discovery, biosynthesis and characterisation of novel anti-microbial lanthipeptides.Read moreRead less
Flexible and Printable Sensors for Early Detection of Food Spoilage . This project aims to develop a technological platform for the fabrication of flexible sensors that enable the detection of food spoilage and life threatening microbial contamination. By engineering stimuli-responsive inks, colorimetric, chemiresistive, and impedimetric sensor arrays will be printed on flexible plastics and paper substrates. The printed sensor arrays will respond to gases and volatile compounds generated from f ....Flexible and Printable Sensors for Early Detection of Food Spoilage . This project aims to develop a technological platform for the fabrication of flexible sensors that enable the detection of food spoilage and life threatening microbial contamination. By engineering stimuli-responsive inks, colorimetric, chemiresistive, and impedimetric sensor arrays will be printed on flexible plastics and paper substrates. The printed sensor arrays will respond to gases and volatile compounds generated from food deterioration and spoilage, microbial pathogen, temperature and pH by a change in their colour or electrical properties, hence providing real-time measurements. The project will enable to design efficient data-driven decision making tools along the supply chain to enhance food safety and reduce food waste. Read moreRead less
Managing uncertainty in RFID traceability networks. Australia suffers 5.4 million cases of food-borne illness every year, which leads to 2.1 million days of lost work, 1.2 million people visiting a doctor, and 120 deaths annually. This has revealed the urgent need for improved ways of locating and recalling problematic products that have been released into the community. The project will develop novel techniques driven by Radio Frequency Identification (RFID) technology for improving the effici ....Managing uncertainty in RFID traceability networks. Australia suffers 5.4 million cases of food-borne illness every year, which leads to 2.1 million days of lost work, 1.2 million people visiting a doctor, and 120 deaths annually. This has revealed the urgent need for improved ways of locating and recalling problematic products that have been released into the community. The project will develop novel techniques driven by Radio Frequency Identification (RFID) technology for improving the efficiency and accuracy of product tracking in distribution networks. This project will place Australia at the forefront of RFID research. It will also be an excellent vehicle for educating young researchers and engineers in Australia.Read moreRead less
Are nutrients the key driver in stimulating toxic algae in subtropical water reservoirs? This project aims to determine the key factors causing blooms of the toxic algae, Cylindrospermopsis raciborskii, which dominates many freshwater reservoirs throughout Queensland. Little is known of why blooms of this species occur. Without the development of this understanding and research capacity to tackle this issue in Queensland, the severity of the problem is likely to increase, putting ever-greater ....Are nutrients the key driver in stimulating toxic algae in subtropical water reservoirs? This project aims to determine the key factors causing blooms of the toxic algae, Cylindrospermopsis raciborskii, which dominates many freshwater reservoirs throughout Queensland. Little is known of why blooms of this species occur. Without the development of this understanding and research capacity to tackle this issue in Queensland, the severity of the problem is likely to increase, putting ever-greater pressure on drinking water supplies. The outcomes from this project would therefore be an increased capacity to predict blooms, and identification of management options for reducing the occurrence of blooms to ensure a cost-effective and safe water supply.Read moreRead less
Identifying and controlling the source of Campylobacter and Salmonella in Australia. This project will identify the source of foodborne illnesses due to Salmonella and Campylobacter in order to inform food regulatory policy. The ultimate aim is to reduce the amount of foodborne disease in Australia.
A Novel Rheological and Chewing and Swallowing model for the Smart Design of Texture Modified Foods for Increased Aged Health. Difficulty in chewing and swallowing mean about 40% of elderly people require Texture Modified (TM) meals. Elders able to eat only very soft food textures have a 2.4 fold higher risk of mortality. However existing methods to assess the level of texture modification are poor; achieving a consistent level of TM meal is difficult; and TM meals have poor sensory properties ( ....A Novel Rheological and Chewing and Swallowing model for the Smart Design of Texture Modified Foods for Increased Aged Health. Difficulty in chewing and swallowing mean about 40% of elderly people require Texture Modified (TM) meals. Elders able to eat only very soft food textures have a 2.4 fold higher risk of mortality. However existing methods to assess the level of texture modification are poor; achieving a consistent level of TM meal is difficult; and TM meals have poor sensory properties (appearance, flavour, aroma). This work will use a novel chewing and swallowing model in conjunction with novel food flavour and property measurements to develop new texture modified foods with increased taste, ease of swallowing and nutritional value.Read moreRead less
New fertiliser technologies for sustained food security. This project aims to provide fundamental research to develop next-generation fertiliser products that will improve nitrogen use efficiency, and reduce nitrogen losses in food production systems. It will achieve this goal through a multidisciplinary approach combining experts in synthetic and free radical chemistry, chemical engineering and soil science, with a strong commitment from a fertiliser industry partner. Society is facing the tri ....New fertiliser technologies for sustained food security. This project aims to provide fundamental research to develop next-generation fertiliser products that will improve nitrogen use efficiency, and reduce nitrogen losses in food production systems. It will achieve this goal through a multidisciplinary approach combining experts in synthetic and free radical chemistry, chemical engineering and soil science, with a strong commitment from a fertiliser industry partner. Society is facing the triple challenges of food security, environmental degradation and climate change The availability of new, highly-efficient fertilisers is critical for addressing these challenges, and for the competitive advantage of the Australian fertiliser industry.Read moreRead less