Enzymatic synthesis, microencapsulation and biological evaluation of a new class of omega-3 derived functional food ingredients. Inflammatory mediated diseases such as cardiovascular disease, type-2 diabetes, metabolic syndrome and Alzheimer's disease are major causes of death in Australia. Rates of these diseases are rising over time, partly due to poor diet including low consumption levels of healthy omega-3 fatty acids from fish. This project aims to develop healthy food ingredients from natu ....Enzymatic synthesis, microencapsulation and biological evaluation of a new class of omega-3 derived functional food ingredients. Inflammatory mediated diseases such as cardiovascular disease, type-2 diabetes, metabolic syndrome and Alzheimer's disease are major causes of death in Australia. Rates of these diseases are rising over time, partly due to poor diet including low consumption levels of healthy omega-3 fatty acids from fish. This project aims to develop healthy food ingredients from naturally occurring omega-3 fatty acid derivatives that are more stable to oxidation and more biologically active than fish derived omega-3 fatty acids. The development of these omega-3 derivatives as functional food ingredients could provide an additional strategy for helping to prevent the rapid increase in inflammatory mediated diseases in the Australian population.Read moreRead less
New nanocomposites of porous materials and visible light sensitive TiO2 for efficient wastewater purification. The innovative newly proposed materials can trap and efficiently decompose dissolved organics in the same process, without generating any waste for disposal. No UV is required and the solar radiation can be efficiently used. The proposed research will be a significant breakthrough in the field of water treatment that reduces energy consumption, uses low cost materials and provides a rea ....New nanocomposites of porous materials and visible light sensitive TiO2 for efficient wastewater purification. The innovative newly proposed materials can trap and efficiently decompose dissolved organics in the same process, without generating any waste for disposal. No UV is required and the solar radiation can be efficiently used. The proposed research will be a significant breakthrough in the field of water treatment that reduces energy consumption, uses low cost materials and provides a real solution. The research findings will be useful to a wide spectrum of manufacturing industries which are currently generating slightly contaminated wastewater, and will be beneficial to the community in general. At the same time, the industries will be a step forward toward sustainable manufacturing.Read moreRead less
Development and application of an index for substantiating health benefits of omega-3 enriched foods. A cost-effective means of substantiating health claims for omega-3 (w3) rich functional foods is needed to fully exploit growing consumer demand for these products. In a two-stage approach, cardiovascular and anti-inflammatory benefits of w3 will be assessed in human dietary trials; improvements of health status in response to graded doses of w3 supplements will be correlated with docosahexaenoi ....Development and application of an index for substantiating health benefits of omega-3 enriched foods. A cost-effective means of substantiating health claims for omega-3 (w3) rich functional foods is needed to fully exploit growing consumer demand for these products. In a two-stage approach, cardiovascular and anti-inflammatory benefits of w3 will be assessed in human dietary trials; improvements of health status in response to graded doses of w3 supplements will be correlated with docosahexaenoic acid (DHA) levels in erythrocytes (DHA Index). Simple bioavailability trials can then be used to determine the intakes of foods required to attain the DHA Index, thus confirming their potential to deliver specified health benefits. Initial trials will support health claims for w3 rich fresh pork and processed pork products.Read moreRead less
Maximising the value of Australia’s sheepmeat industry with smart photonics. This project aims to investigate new photonics technologies to measure meat quality in lamb and mutton. It expects to develop new knowledge in the areas of fibre optics and 3D printing for use by the red meat and livestock industries. Expected outcomes of this project include development of a new technology to rapidly identify premium meat during meat processing. This should provide significant benefits for Australia’s ....Maximising the value of Australia’s sheepmeat industry with smart photonics. This project aims to investigate new photonics technologies to measure meat quality in lamb and mutton. It expects to develop new knowledge in the areas of fibre optics and 3D printing for use by the red meat and livestock industries. Expected outcomes of this project include development of a new technology to rapidly identify premium meat during meat processing. This should provide significant benefits for Australia’s red meat industry, helping to establish Australia as a leading supplier of high-quality meat to domestic and international markets.Read moreRead less
ARC Centre of Excellence in Plants for Space. ARC Centre of Excellence in Plants for Space. This Centre aims to create on-demand, zero-waste, high-efficiency plants and plant products to address grand challenges in sustainability for Space and on Earth. Significant advances in plant, food, and sensory science; process and systems engineering; law and policy; and psychology are expected to deliver transformative solutions for Space habitation – and create enhanced plant-derived food and bioresour ....ARC Centre of Excellence in Plants for Space. ARC Centre of Excellence in Plants for Space. This Centre aims to create on-demand, zero-waste, high-efficiency plants and plant products to address grand challenges in sustainability for Space and on Earth. Significant advances in plant, food, and sensory science; process and systems engineering; law and policy; and psychology are expected to deliver transformative solutions for Space habitation – and create enhanced plant-derived food and bioresources to capitalise upon emergent and rapidly expanding domestic and global markets. Anticipated outcomes include industry uptake of innovative plant forms, foods, technologies, and commodities; and an ambitious education and international co-ordination agenda to position Australia as a global leader in research supporting Space habitation.Read moreRead less
Evaluation of High-Power Ultrasound as an Innovative Tool for Sanitation, Colour/Flavour Extraction and Fermentation Enhancement in Wine Making. The multibillion-dollar wine industry forms a significant part of the Australian economy especially in regional areas. The application of high power ultrasound (HPU) to the cleaning and disinfection of wine barrels as well as for the enhancement of wine through improved fermentation and extraction of flavours and colours from grapes will have significan ....Evaluation of High-Power Ultrasound as an Innovative Tool for Sanitation, Colour/Flavour Extraction and Fermentation Enhancement in Wine Making. The multibillion-dollar wine industry forms a significant part of the Australian economy especially in regional areas. The application of high power ultrasound (HPU) to the cleaning and disinfection of wine barrels as well as for the enhancement of wine through improved fermentation and extraction of flavours and colours from grapes will have significant benefits to this industry. It is essential that Australia also capitalise on the benefits that this technology can provide in improved processing and products, lower costs, reduction in environmental pollution, water re-use and replacement of "dirty" energy. In this way the impact on this industry will help cement Australia's position in the world wine market long into the future.Read moreRead less
Development of novel omega-3 enriched poultry products. New Health recommendations and changes to the Food Standards Code encourage greater dietary intake of omega-3 (w-3) fatty acids. Our core research on modifying fatty acid composition of poultry tissues and preliminary studies with our industry partner's proprietary fishmeal product (PorcOmega) have indicated the feasibility of producing novel meat products and eggs with high w-3 contents, which would qualify to carry a new nutrition label. ....Development of novel omega-3 enriched poultry products. New Health recommendations and changes to the Food Standards Code encourage greater dietary intake of omega-3 (w-3) fatty acids. Our core research on modifying fatty acid composition of poultry tissues and preliminary studies with our industry partner's proprietary fishmeal product (PorcOmega) have indicated the feasibility of producing novel meat products and eggs with high w-3 contents, which would qualify to carry a new nutrition label. We now propose, in collaboration with our industry partner, to assess the viability of producing such products by conducting poultry feeding trials with PorcOmega on a commercial scale and evaluating both the levels of w-3 enrichement of chicken breast, thigh and sausages, shelf-life and consumer acceptability (sensory evaluation) of these products. We expect to establish feeding strategies for adoption by commercial producers of premium poultry and eggs for local or export markets.Read moreRead less
Development of Multilayered Packaging Materials with Controlled Barrier Properties. The project aims to develop advanced new material for multilayered packaging with high oxygen and moisture barrier properties for cost effective packaging applications. Poly Products currently imports and uses some polymer as its key component for controlling barrier property of their food packaging. However, the new nanostructured material when sandwiched between less expensive materials in a multilayered packag ....Development of Multilayered Packaging Materials with Controlled Barrier Properties. The project aims to develop advanced new material for multilayered packaging with high oxygen and moisture barrier properties for cost effective packaging applications. Poly Products currently imports and uses some polymer as its key component for controlling barrier property of their food packaging. However, the new nanostructured material when sandwiched between less expensive materials in a multilayered packaging film will yield excellent barrier properties, leading to extended shelf life of different food products. The new smart material will generate significant material saving and replace the imported polymer, and will secure export market of the product in Asia -Pacific region.Read moreRead less
Protein biosensors for detecting smoke exposure of grapes. Bush fires and controlled burns that take place in the vicinity of vineyards can lead to grape contamination with tasteless phenolic glucosides. Their hydrolysis during wine making leads to “smoke taint” – an unpleasant medicinal taste that can render wine undrinkable. We will apply a combination of organic synthesis, protein engineering and directed evolution to develop protein-based biosensors of phenolic glucosides. These biosensors w ....Protein biosensors for detecting smoke exposure of grapes. Bush fires and controlled burns that take place in the vicinity of vineyards can lead to grape contamination with tasteless phenolic glucosides. Their hydrolysis during wine making leads to “smoke taint” – an unpleasant medicinal taste that can render wine undrinkable. We will apply a combination of organic synthesis, protein engineering and directed evolution to develop protein-based biosensors of phenolic glucosides. These biosensors will be used to devise a simple portable colorimetric test that can be performed in the vineyard or the winery. The ability to rapidly determine the level of grape contamination with phenolic glucosides would give Australian wine growers and wine makers a powerful tool to mitigate the effects of bushfires.Read moreRead less
Probiotic Prawn Oral Immunotherapy (ProPIT) For Treatment Of Prawn Allergy
Funder
National Health and Medical Research Council
Funding Amount
$1,865,369.00
Summary
A ‘curative’ food allergy treatment is needed to prevent deaths and improve care. We recently showed that probiotic peanut oral immunotherapy (PPOIT) was highly effective for treating peanut allergy. 82% of PPOIT treated children gained tolerance compared to 4% of the placebo group. We will now test the combined probiotic-food OIT approach for treating prawn allergy. If successful, we will have identified the first treatment for prawn allergy and a platform treatment for other food allergies.