Linkage Infrastructure, Equipment And Facilities - Grant ID: LE160100194
Funder
Australian Research Council
Funding Amount
$250,000.00
Summary
Optical diagnostics for the investigation of high-speed energetic processes. Optical diagnostics for the investigation of high-speed energetic processes:
The project seeks to establish equipment to enable the investigation of high-speed energetic processes. Such processes, where large amounts of energy are released over a short time frame, occur in nature and almost every field of science and engineering, and their investigation is a formidable challenge. This challenge is designed to be met th ....Optical diagnostics for the investigation of high-speed energetic processes. Optical diagnostics for the investigation of high-speed energetic processes:
The project seeks to establish equipment to enable the investigation of high-speed energetic processes. Such processes, where large amounts of energy are released over a short time frame, occur in nature and almost every field of science and engineering, and their investigation is a formidable challenge. This challenge is designed to be met through the combined use of state-of-the-art flow visualisation, thermography and spectrometry equipment. These diagnostics would open avenues into so far impossible or difficult to conduct research on highly transient phenomena in various research fields, which include various aspects of fluid mechanics, combustion, and fracture mechanics. The equipment would be instrumental in the design of better and innovative machines, materials, instruments and processes.Read moreRead less
Bright x-ray beams from laser-driven microplasmas. This project aims to develop a new generation of bright, laser-like x-ray sources for laboratory use. X-ray sources underpin key diagnostic techniques in materials science, advancing applications from structural engineering through to ore processing and energy storage. However, the limited brightness of present-day laboratory x-ray sources restricts the utility and range of these diagnostic techniques. This research intends to use intense lasers ....Bright x-ray beams from laser-driven microplasmas. This project aims to develop a new generation of bright, laser-like x-ray sources for laboratory use. X-ray sources underpin key diagnostic techniques in materials science, advancing applications from structural engineering through to ore processing and energy storage. However, the limited brightness of present-day laboratory x-ray sources restricts the utility and range of these diagnostic techniques. This research intends to use intense lasers to create microscopic plasmas and drive high harmonic generation. The high harmonic generation process is already used to create laser-like ultraviolet light. By optimising the characteristics of the plasma medium, the project aims to extend bright high harmonic generation to the x-ray regime.Read moreRead less
Integrin Activation by Fluid Flow Disturbance: Mechanobiology Approaches. Understanding how cells can sense and respond to mechanical environment such as dynamic blood flow represents a fundamental question in the emerging field of mechanobiology. This project develops new biomechanical engineering approaches to determine the critical interrelationships among fluid flow disturbance, platelet clotting and the mechano-sensitive signal transduction mechanisms of integrin receptor – the most importa ....Integrin Activation by Fluid Flow Disturbance: Mechanobiology Approaches. Understanding how cells can sense and respond to mechanical environment such as dynamic blood flow represents a fundamental question in the emerging field of mechanobiology. This project develops new biomechanical engineering approaches to determine the critical interrelationships among fluid flow disturbance, platelet clotting and the mechano-sensitive signal transduction mechanisms of integrin receptor – the most important mechano-sensor implicated in cell adhesion, migration, growth and survival. Specifically, it integrates nationally unique cutting-edge techniques including single-molecule force probe, microparticle image velocimetry, microfluidics and molecular dynamics simulation, super resolution and 3D volumetric imaging modalities.Read moreRead less
Australian Laureate Fellowships - Grant ID: FL230100023
Funder
Australian Research Council
Funding Amount
$3,362,355.00
Summary
Highly efficient microscale liquid handling and bio interfacing. The aim is to establish the exciting new field of micro elastofluidics, enabling the development of a highly competitive, sovereign capability in Australia, utilising flexibility and stretchability for efficient and precise handling of tiny volumes of liquid. The program will fill a critical gap in fundamental knowledge in fluid-structure interactions, leading to the development of wearable and implantable devices. The expected out ....Highly efficient microscale liquid handling and bio interfacing. The aim is to establish the exciting new field of micro elastofluidics, enabling the development of a highly competitive, sovereign capability in Australia, utilising flexibility and stretchability for efficient and precise handling of tiny volumes of liquid. The program will fill a critical gap in fundamental knowledge in fluid-structure interactions, leading to the development of wearable and implantable devices. The expected outcomes include innovative platform technologies for sample storage, handling and unique device-human interfaces with broad applications in health and defence. Expected benefits include enhanced capabilities in medical diagnostics, defence force protection and Australia’s sovereign high-tech manufacturing.Read moreRead less
Cell–fluid interaction: inside and outside cells. The project aims to measure mechanics at the cellular level using a combination of optical tweezers for measurement of nano-scale environment around/inside cells and light-sheet microscopy for imaging. The project expects to generate new knowledge about movement of cells through their environment, relating to collective behaviour which is of importance in understanding infections and formation of biofilms. Expected outcomes include deepened under ....Cell–fluid interaction: inside and outside cells. The project aims to measure mechanics at the cellular level using a combination of optical tweezers for measurement of nano-scale environment around/inside cells and light-sheet microscopy for imaging. The project expects to generate new knowledge about movement of cells through their environment, relating to collective behaviour which is of importance in understanding infections and formation of biofilms. Expected outcomes include deepened understanding of an enigmatic process conserved from amoebae to humans, by which cells ‘drink and eat’ by ‘gulping’ fluid and supplement their nutrient intake by degrading proteins and cell debris. It will generate new knowledge of these processes to better understand how mechanics affects cellular life.Read moreRead less
ARC Centre of Excellence in Quantum Biotechnology. ARC Centre of Excellence in Quantum Biotechnology. The ARC Centre of Excellence in Quantum Biotechnology aims to develop paradigm-shifting quantum technologies to observe biological processes and transform our understanding of life. It seeks to create technologies that go far beyond what is possible today, from portable brain imagers to super-fast single protein sensors, and to use them to unravel key problems including how enzymes catalyse reac ....ARC Centre of Excellence in Quantum Biotechnology. ARC Centre of Excellence in Quantum Biotechnology. The ARC Centre of Excellence in Quantum Biotechnology aims to develop paradigm-shifting quantum technologies to observe biological processes and transform our understanding of life. It seeks to create technologies that go far beyond what is possible today, from portable brain imagers to super-fast single protein sensors, and to use them to unravel key problems including how enzymes catalyse reactions and how higher brain function emerges from networks of neurons. By building a diverse, multidisciplinary, and industry-engaged ecosystem, the Centre means to develop our future leaders at the interface of quantum science and biology and drive Australian innovation across manufacturing, energy, agriculture, health, and national security.Read moreRead less
Non-classical motion of a macroscopic mechanical resonator. This project will create the experimental tools to fully control the motion of a mechanical oscillator at the single-quanta level, opening a rich avenue for fundamental research and the development of quantum physics enhanced applications. This project will prepare a quantum state of a macroscopic mechanical resonator exhibiting quantum interference fringes at at an unprecedented mass scale. The observation of these fringes will enable ....Non-classical motion of a macroscopic mechanical resonator. This project will create the experimental tools to fully control the motion of a mechanical oscillator at the single-quanta level, opening a rich avenue for fundamental research and the development of quantum physics enhanced applications. This project will prepare a quantum state of a macroscopic mechanical resonator exhibiting quantum interference fringes at at an unprecedented mass scale. The observation of these fringes will enable the study of the intricacies of quantum decoherence and ultimately even probe quantum gravitational phenomena. To achieve these goals it will employ micro-scale optical resonators fabricated by established techniques, that also provide the ideal platform for scalable mechanical-oscillator-based quantum information applications.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE210100934
Funder
Australian Research Council
Funding Amount
$439,082.00
Summary
Taming the light: full control in polarisation, space, and time. This project aims to develop two prototype optical beam shaping systems, culminating in the demonstration of new high-power optical fibre amplifiers. This novel ability to control all the properties of light enables the generation of optical beams that were only theoretical ideas but never previously implemented experimentally. This advanced technology can potentially open new ways in which objects can be probed using light. Expect ....Taming the light: full control in polarisation, space, and time. This project aims to develop two prototype optical beam shaping systems, culminating in the demonstration of new high-power optical fibre amplifiers. This novel ability to control all the properties of light enables the generation of optical beams that were only theoretical ideas but never previously implemented experimentally. This advanced technology can potentially open new ways in which objects can be probed using light. Expected outcomes include the creation of an optical platform that the optical community at large may utilise for their specific applications. Besides the intellectual property benefits of such optical devices directly, this project should bridge the gap between the developed knowledge and commercial opportunities.Read moreRead less
Control of light in space and time in multimode optical fibres. This project aims to create devices to measure and manipulate the spatial and temporal properties of light. The ability to control or measure the spatial and/or temporal properties of light is a fundamental feature of many applications, including biomedical imaging, astronomy, telecommunications, high-power lasers and quantum computing. This project will develop five prototype systems to control the spatiotemporal properties of ligh ....Control of light in space and time in multimode optical fibres. This project aims to create devices to measure and manipulate the spatial and temporal properties of light. The ability to control or measure the spatial and/or temporal properties of light is a fundamental feature of many applications, including biomedical imaging, astronomy, telecommunications, high-power lasers and quantum computing. This project will develop five prototype systems to control the spatiotemporal properties of light in ways that were previously not possible. This would affect fundamental and applied applications where the inability to sufficiently control light’s spatial and/or temporal properties is an impediment. Examples include imaging deep into ‘opaque’ objects such as human skin or brain, high-power lasers for material processing and manufacturing, optical telecommunications and quantum computation.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE120101899
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Developing the next generation of single and entangled photon sources. Low noise and efficient sources of single and entangled photons are important resources to implement a scalable platform for large-scale quantum information tasks. This project will develop the prototypes for these sources which will be suitable for a wide range of interesting applications in quantum information.