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Translating Advances In Cell-free Fetal Nucleic Acids Into Better Perinatal Care
Funder
National Health and Medical Research Council
Funding Amount
$187,322.00
Summary
My overall aim is to translate advances in biotechnology into better care for pregnant women. My first aim is to study brain development by analyzing the fluid that surrounds the unborn baby. This work may provide more information to women about their baby’s expected outcome. My second aim is to evaluate the impact of new DNA technologies on the detection of genetic conditions in the baby before birth. This work will confirm if this new generation of tests is fulfilling our high expectations.
Safer Fluid Resuscitation- Which (type), What (to Expect) And How (mechanisms)
Funder
National Health and Medical Research Council
Funding Amount
$189,384.00
Summary
Intravenous fluid administration to patients is the most common clinical intervention, often done to help sick patents get better, however paradoxically it is associated with worsening oxygen levels and increased death rates. In humans and animal I have demonstrated increased respiratory dysfunction with its administration. This study aims to understand the efficacy, compare different types of fluids and establish safer fluid administration thereby decreasing patient suffering and death rates.
Optimisation Of The Supportive Care Of Adults With Severe Falciparum Malaria
Funder
National Health and Medical Research Council
Funding Amount
$239,346.00
Summary
In the last two decades the care of patients with severe malaria has been revolutionised by the discovery of new drugs that reduce the chance of dying by 30% when compared to the previous standard treatments. However even with the use of these drugs, up to 30% of adults and 10% of children with severe malaria will still die from the disease. We need a greater understanding of how malaria harms people so that we might develop new drugs and treatment strategies to improve outcomes.