A Grid based platform for multi-scaled biological simulation. Heart disease currently affects over 3.5 million Australians. In 2006 it claimed the lives of almost 46,000 Australians (34% of all deaths). We will develop enabling technology that underpins cardiac disease research, offering potential for new treatments and pharmaceutical therapies. Even a small improvement in this area can translate into significant national benefit. Further, the mathematical techniques and software tools we will d ....A Grid based platform for multi-scaled biological simulation. Heart disease currently affects over 3.5 million Australians. In 2006 it claimed the lives of almost 46,000 Australians (34% of all deaths). We will develop enabling technology that underpins cardiac disease research, offering potential for new treatments and pharmaceutical therapies. Even a small improvement in this area can translate into significant national benefit. Further, the mathematical techniques and software tools we will develop, whilst focused on heart tissue, will have broader applicability, and may underpin advancements in other disciplines. Finally, we expect that the software solutions and infrastructure will have both commercial and strategic value in their own right.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0453911
Funder
Australian Research Council
Funding Amount
$391,529.00
Summary
Microwave Antenna Testing Facility for Far-Field and Spherical Near-Field Measurements. The proposed facility is for testing broad-beam microwave antennas (1 GHz - 18 GHz), designed and developed by collaborators for several research and commercial projects. These antennas are important in telecommunications, defence and biomedical applications. While facilitating timely pattern measurements of antenna prototypes, it will open new opportunities in antenna experimentation. This facility will enha ....Microwave Antenna Testing Facility for Far-Field and Spherical Near-Field Measurements. The proposed facility is for testing broad-beam microwave antennas (1 GHz - 18 GHz), designed and developed by collaborators for several research and commercial projects. These antennas are important in telecommunications, defence and biomedical applications. While facilitating timely pattern measurements of antenna prototypes, it will open new opportunities in antenna experimentation. This facility will enhance collaborators' highly acclaimed theoretical research by providing experimental results for theory validation. Near-field patterns available from the facility will advance our knowledge on complicated antennas. This will generate researchers skilled in state-of-the art antenna measurements, and will help develop competitive Australian industries in this frontier technology.Read moreRead less
Quantification of Traffic Generated Nano and Ultrafine Particle Dynamics and Toxicity in Transit Hubs and Transport Corridors. The socio-economic benefits to Australia will include (i) new knowledge for the multiparameter assessment of nano and ultrafine particles, pollutants in the centre of current scientific, medical and policy debates (ii) a breakthrough in the scientific understanding of traffic generated particles in the urban atmosphere (iii) determining the toxicological impact of these ....Quantification of Traffic Generated Nano and Ultrafine Particle Dynamics and Toxicity in Transit Hubs and Transport Corridors. The socio-economic benefits to Australia will include (i) new knowledge for the multiparameter assessment of nano and ultrafine particles, pollutants in the centre of current scientific, medical and policy debates (ii) a breakthrough in the scientific understanding of traffic generated particles in the urban atmosphere (iii) determining the toxicological impact of these particles on biological systems. The ultimate economic benefit will be improved urban design to lower human exposure to ultrafine particles, thus reducing health care cost and productivity losses. The research will also place Australia at the forefront of international progress towards better methods for achieving environmental sustainability.Read moreRead less
Fractional dynamic models for MRI to probe tissue microstructure. This project aims to develop new mathematical tools for mapping tissue microstructural properties via the use of space-time fractional calculus methods. In magnetic resonance imaging, mathematical models and their parameters play a key role in associating information between images and biology, with the overall aim of producing spatially resolved maps of tissue property variations. However, models which can inform on changes in mi ....Fractional dynamic models for MRI to probe tissue microstructure. This project aims to develop new mathematical tools for mapping tissue microstructural properties via the use of space-time fractional calculus methods. In magnetic resonance imaging, mathematical models and their parameters play a key role in associating information between images and biology, with the overall aim of producing spatially resolved maps of tissue property variations. However, models which can inform on changes in microscale tissue properties are lacking. The tools developed by this project will be used to generate new magnetic resonance image based maps to convey information on tissue microstructure changes in the human brain. Additionally, the mathematical tools developed will be transferable to other applications where diffusion and transport in heterogeneous porous media play a role.Read moreRead less