Health Coaching Intervention To Prevent Excessive Gestational Weight Gain
Funder
National Health and Medical Research Council
Funding Amount
$98,507.00
Summary
Excessive weight gain in pregnancy places women at a greater risk for the development of overweight and obesity. This study responds to the urgent need to design effective interventions to prevent excessive weight gain in pregnancy. A health coaching intervention has been designed to address this need, and its effectiveness will be evaluated in a randomised controlled trial with first time pregnant women.
Better Data To Inform Interventions To Reduce The Risk Of Stillbirth In Australia
Funder
National Health and Medical Research Council
Funding Amount
$75,830.00
Summary
Stillbirth is a devastating experience for parents and families. Paucity of high quality data on causes and contributing factors is a major barrier to the development of research priorities and interventions to prevent stillbirths and improve the quality of care. This research will be a connected body of work that aims to better describe the epidemiology of stillbirth in Australia, contribute to the classification of stillbirths and determine the needs of parents in relation to autopsy consent.
Loop-mediated Isothermal Amplification(LAMP): A Novel Tool For The Diagnosis Of Mixed Malaria Infections In Elimination Settings
Funder
National Health and Medical Research Council
Funding Amount
$101,877.00
Summary
The malaria elimination agenda will require the development of novel, field applicable diagnostic tools to detect asymptomatic carriers of P.falciparum and non-falciparum malaria infections. Loop-mediated isothermal amplification (LAMP) has been demonstrated to be a novel, sensitive, specific nucleic acid amplification technique. My project aims to optimise LAMP into a high-throughput field applicable molecular diagnostic tool capable of diagnosing malaria in elimination settings
Health Consequences For Mother And Baby Of Substantial Pre-conception Weight Loss In Obese Women
Funder
National Health and Medical Research Council
Funding Amount
$93,418.00
Summary
Obesity (BMI >30kg/m2) is now very common in women of child-bearing age.There is strong evidence that maternal obesity increases the rate of pregnancy complications, and affects the growth and well-being of the fetus in-utero. This project aims to determine how substantial pre-conception weight loss, achieved using a Very Low Energy Diet (VLED), impacts maternal and neonatal health outcomes.
A Brief Couple-focused Psycho-educational Intervention To Prevent Postnatal Mental Health Problems In Women: A Cluster Randomised Trial
Funder
National Health and Medical Research Council
Funding Amount
$99,654.00
Summary
Mental health problems in women after childbirth are of national concern. Interventions to prevent these have had little success. What Were We Thinking (WWWT) is a promising new program for mothers, fathers and newborns. It provides knowledge and skills about soothing and settling babies and enhancing parents’ understanding of their changed needs and how to share the workload fairly. This trial will test whether WWWT improves women’s mental health in the first six months of motherhood
The Molecular Epidemiology Of Malaria Transmission In The Solomon Islands
Funder
National Health and Medical Research Council
Funding Amount
$69,098.00
Summary
The recent dramatic reduction in malaria burden has prompted a shift from control to elimination and aims to interrupt malaria transmission itself. Achieving this requires the development of set tools that directly target transmission. Little is known about the epidemiology of malaria transmission in the SW Pacific. The goal of this PhD project is to determine the dynamics of malaria transmission in Solomon Islands using a combination of large epidemiological studies and novel molecular assays.
Indwelling Pleural Catheter For Management Of Cancer-related Pleural Effusions
Funder
National Health and Medical Research Council
Funding Amount
$123,688.00
Summary
Most cancers can be complicated by fluid accumulation (effusion) in the (pleural) cavity between the lung and chest wall, causing significant breathlessness. Indwelling pleural catheter (IPC) is a new method that allows patients to drain the effusion outside the hospital and avoid further invasive interventions. This study aims to provide important information that will help guide use of IPC and manage its complications, especially infection, improve patient outcomes and save healthcare costs.
Disease Burden, Risk Factors And Treatment Of Knowlesi Malaria
Funder
National Health and Medical Research Council
Funding Amount
$95,564.00
Summary
Plasmodium knowlesi is a form of monkey malaria recently found to also cause increasing numbers of natural infections in humans in South-East Asia. This research will describe the burden of P. knowlesi malaria in an area of Malaysian Borneo. The risk factors for acquiring P. knowlesi malaria will be assessed. Finally the optimal treatment for non-severe cases of P. knowlesi and P. vivax malaria will also be evaluated by comparing the 2 currently recommended anti-malarial medications in Malaysia.
Establishing The Use Of Bacterial Genomics In Australia
Funder
National Health and Medical Research Council
Funding Amount
$157,669.00
Summary
We propose to establish a set of fully assembled reference genomes through new technologies and methods to analyse data from high throughput genome sequencing of important bacterial pathogens in Australia. We aim to demonstrate the capabilities of genome sequencing in clinical situations by comparing the genomes from clinical bacterial isolates to the established and annotated reference genomes.
Double Blind, Randomised Controlled Trial Assessing The Efficacy Of Endothelin-1 Receptor Antagonism In Preventing Peri-procedural Myonecrosis In Patients With Non-ST Elevation Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention
Funder
National Health and Medical Research Council
Funding Amount
$124,608.00
Summary
While the focus in the treatment of coronary artery disease has primarily been on the large vessels in the heart, vessels of small calibre may also play a significant role in patients with angina, heart attack, and muscle injury related to a stenting procedure.This project aims elucidate the possible mechanisms which cause dysfunction in these small vessels. I also hope to find a treatment strategy which may benefit patients with small vessel problems and thus improve their overall outcome.