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To Investigate Rates Of Peritonitis In Incident Peritoneal Dialysis Patients In Australia And Perform A Pilot Study Aimed At Reducing These Rates
Funder
National Health and Medical Research Council
Funding Amount
$92,314.00
Summary
Overall aims: To establish how much variation in PD practice exists between renal units in Australia; to establish current practice in 8 units; to perform an intervention study in 8 units; to analyse registry data re peritonitis in PD patients; to conduct interviews with PD patients who have had peritonitis. Expected outcomes: To establish if practice variation is associated with peritonitis rates; to see if active guideline implementation leads to better peritonitis rates; to establish the reas ....Overall aims: To establish how much variation in PD practice exists between renal units in Australia; to establish current practice in 8 units; to perform an intervention study in 8 units; to analyse registry data re peritonitis in PD patients; to conduct interviews with PD patients who have had peritonitis. Expected outcomes: To establish if practice variation is associated with peritonitis rates; to see if active guideline implementation leads to better peritonitis rates; to establish the reasons why therapy fails.Read moreRead less
Vitamin D And Acute Lower Respiratory Tract Infection (ALRI) In Indigenous Children
Funder
National Health and Medical Research Council
Funding Amount
$92,669.00
Summary
Australian Indigenous children experience extreme rates of acute lower respiratory infection (ALRI) that medical interventions have failed to reduce. Vitamin D is an important immunoregulatory molecule of the respiratory system that remains uncharacterised in this population. We propose that deficiency contributes to the persistent rates of ALRI. This study will characterise vitamin D levels in a cohort of Indigenous children with and without ALRI. The results will guide future intervention.
A Detailed Asssessment Of Severe Malaria And Severe Non Malarial Illness In Papua New Guinean Children.
Funder
National Health and Medical Research Council
Funding Amount
$39,171.00
Summary
PNG has the highest infant and childhood mortality in the Pacific with malaria accounting for 15% of infant mortality. Diagnosing and investigating malaria in this setting is hard because the symptoms are similar to other diseases. We aim to accurately describe clinical and laboratory features and risk factors for malaria, severe non malarial disease and mortality. We are investigating an outbreak of unexplained encephalitis as well.
A Study Of The Relationship Between Vitamin D Status And The Severity And Outcomes Of Chronic Non-cholestatic Liver Disease
Funder
National Health and Medical Research Council
Funding Amount
$133,351.00
Summary
Vitamin D deficiency is associated with common and severe conditions such as cancer, cardiovascular disease, autoimmune disease and diabetes. Recent studies suggest that vitamin D deficiency also worsens the severity and prognosis of chronic liver disease and that vitamin D replacement may improve outcomes. This research will further investigate the relationship of vitamin D deficiency to liver disease caused by the common conditions hepatitis B and C and non-alcoholic fatty liver disease and th ....Vitamin D deficiency is associated with common and severe conditions such as cancer, cardiovascular disease, autoimmune disease and diabetes. Recent studies suggest that vitamin D deficiency also worsens the severity and prognosis of chronic liver disease and that vitamin D replacement may improve outcomes. This research will further investigate the relationship of vitamin D deficiency to liver disease caused by the common conditions hepatitis B and C and non-alcoholic fatty liver disease and the impact of vitamin D replacement.Read moreRead less