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Porous Silica-Based Nanocapsules for Targeted and Controlled Release of Biocides. The project will lead to significant advances in nanotechnology and agrichemical biocide applications. A highly efficient insect control technology will be developed, that will be cost-effective with the ability for targeted control and release of biocides. The encapsulation technology will reduce the total usage and costs of biocides thus benefit the environment in terms of reduced environment pollution and enhanc ....Porous Silica-Based Nanocapsules for Targeted and Controlled Release of Biocides. The project will lead to significant advances in nanotechnology and agrichemical biocide applications. A highly efficient insect control technology will be developed, that will be cost-effective with the ability for targeted control and release of biocides. The encapsulation technology will reduce the total usage and costs of biocides thus benefit the environment in terms of reduced environment pollution and enhanced ecological safety.Read moreRead less
Kinetics of phytochemical adsorption and desorption in clay nanoparticles. Biologically active phytochemicals are of increasing importance in many areas of human endeavour. There is a growing interest in the agricultural uses of such compounds. A major limiting factor has been the control of the release rate and the general susceptibility to UV breakdown. This project aims to develop a platform technology for the controlled release and for improved UV protection of these chemicals. Through the s ....Kinetics of phytochemical adsorption and desorption in clay nanoparticles. Biologically active phytochemicals are of increasing importance in many areas of human endeavour. There is a growing interest in the agricultural uses of such compounds. A major limiting factor has been the control of the release rate and the general susceptibility to UV breakdown. This project aims to develop a platform technology for the controlled release and for improved UV protection of these chemicals. Through the studies on the adsorption and desorption kinetics of select phytochemicals, we aim to develop a nanoparticle clay based carrier system and a predictive model for control of the desorption characteristics. Such a platform technology will enable wide range of applications of phytochemical products in pesticides, plant stress alleviating and growth enhancing areas.Read moreRead less
Clay nanoparticle-facilitated RNAi for non-transgenic modification of crops. This project aims to define the most effective spray formulations, consisting of clay nanoparticles and induced RNA interference (RNAi) to manipulate gene expression in plants. Topical application of double-stranded RNA (dsRNA) for RNAi represents an attractive alternative to genetically engineered crops. However, naked dsRNA is unstable and is not efficiently taken up by plants. For these reasons, topical application o ....Clay nanoparticle-facilitated RNAi for non-transgenic modification of crops. This project aims to define the most effective spray formulations, consisting of clay nanoparticles and induced RNA interference (RNAi) to manipulate gene expression in plants. Topical application of double-stranded RNA (dsRNA) for RNAi represents an attractive alternative to genetically engineered crops. However, naked dsRNA is unstable and is not efficiently taken up by plants. For these reasons, topical application of dsRNA has thus far produced only modest induction of RNAi in plants. Nanoparticle-facilitated manipulation of gene expression in plants will enable sustainable clean green strategies for protecting crops from diseases. This project will result in improved crop protection and productivity and boost the export potential of Australian crops.Read moreRead less
Novel Nano-Pesticides for Animal Healthcare. This project aims to develop a new nano-pesticide with improved safety and performance. Ticks and buffalo fly cause over $400 million each year in economic losses to the Australian livestock industry and are currently treated with highly toxic synthetic pesticides. Spinosad, a naturally derived pesticide with low environmental impact and low toxicity, will be loaded into silica hollow spheres which will improve adhesion to skin or hair and protect aga ....Novel Nano-Pesticides for Animal Healthcare. This project aims to develop a new nano-pesticide with improved safety and performance. Ticks and buffalo fly cause over $400 million each year in economic losses to the Australian livestock industry and are currently treated with highly toxic synthetic pesticides. Spinosad, a naturally derived pesticide with low environmental impact and low toxicity, will be loaded into silica hollow spheres which will improve adhesion to skin or hair and protect against ultraviolet degradation. The nano-spinosad pesticide is expected to have enhanced efficacy and effective duration in field conditions compared to conventional pesticides, significantly reducing the cost of pest control.Read moreRead less
Engineering layered double hydroxide nanoparticles toward an efficient targeted clinical delivery system. This project will develop a more effective drug delivery system using clay nanoparticles and biofriendly serum proteins. Outcomes from this project will provide a tremendous opportunity for potent therapies of cancers, vasculature and neuronal diseases, and place Australia at the forefront of nanotechnology drug delivery research.
ARC Centre of Excellence in Convergent Bio-Nano Science and Technology. The CoE in Convergent Bio-Nano Science &Technology comprises a multi-disciplinary team focused on research aiming to understand and control the interface of materials with biological systems. The Centre will exploit knowledge of the bio-nano interface to design materials that transport and deliver vaccines, drugs and gene therapy agents, and to design new diagnostic agents and devices. Nanomedicines are on the cusp of revol ....ARC Centre of Excellence in Convergent Bio-Nano Science and Technology. The CoE in Convergent Bio-Nano Science &Technology comprises a multi-disciplinary team focused on research aiming to understand and control the interface of materials with biological systems. The Centre will exploit knowledge of the bio-nano interface to design materials that transport and deliver vaccines, drugs and gene therapy agents, and to design new diagnostic agents and devices. Nanomedicines are on the cusp of revolutionizing diagnosis and therapy in many diseases. The CoE will be the focus of bio-nano research activity in Australia, uniting universities, research agencies, institutes and companies. The expected outcomes are better diagnostic and therapeutic tools designed via an enhanced understanding of the bio-nano-interface.Read moreRead less
Smart Nanocapsules for Efficient Cellular Delivery of Bioactive Peptide Drugs. This project will bring about practical benefits in terms of developing efficient therapeutic drug delivery systems, which has a market growth estimated to be ca. 23% p.a. in the world. The novel encapsulation technology developed in this project is not only desirable for biomolecules but also applicable for other functional materials and will find wide applications in a number of fields, such as chemical, food proces ....Smart Nanocapsules for Efficient Cellular Delivery of Bioactive Peptide Drugs. This project will bring about practical benefits in terms of developing efficient therapeutic drug delivery systems, which has a market growth estimated to be ca. 23% p.a. in the world. The novel encapsulation technology developed in this project is not only desirable for biomolecules but also applicable for other functional materials and will find wide applications in a number of fields, such as chemical, food processing and cosmetic industries. Successful completion of the project can also strengthen our capacity to participate in new areas of research and positioning Australia at the forefront of bionanotechnology.Read moreRead less
Numerical Modelling and Experimental Studies to Design and Engineer Nanoparticulate Systems for Bioapplications. Project outcomes will enhance Australia's reputation for scientific innovation in the field of bio-nanotechnology. The project will expand the knowledge base in this area and increase Australia's international profile in research on nanomaterials for bio-related applications. The project partners UNSW and Australian company (Minomic), integrating their skills, expertise and facilities ....Numerical Modelling and Experimental Studies to Design and Engineer Nanoparticulate Systems for Bioapplications. Project outcomes will enhance Australia's reputation for scientific innovation in the field of bio-nanotechnology. The project will expand the knowledge base in this area and increase Australia's international profile in research on nanomaterials for bio-related applications. The project partners UNSW and Australian company (Minomic), integrating their skills, expertise and facilities to address current limitations in understanding the stability of magnetic nanoparticles in biological fluids. The Australian partners will play a leading role in commercializing new applications for functionalized magnetic nanoparticles. The project will provide an excellent multidisciplinary research environment and training for early career researchers.Read moreRead less
TAILORING OF LAYERED DOUBLE HYDROXIDE NANOPARTICLES FOR EFFECTIVE DELIVERY OF BIOLOGICALLY ACTIVE PEPTIDES AND cDNAs. This project will lead to a new class of nanoparticle for effective peptide and DNA transfer, promising efficient drug delivery system with controllable loading and releasing and thus help maintain good health, particularly targeting neurological diseases. This project has also involved fundamental research into the nanomaterial science, surface chemistry, cell biochemistry and n ....TAILORING OF LAYERED DOUBLE HYDROXIDE NANOPARTICLES FOR EFFECTIVE DELIVERY OF BIOLOGICALLY ACTIVE PEPTIDES AND cDNAs. This project will lead to a new class of nanoparticle for effective peptide and DNA transfer, promising efficient drug delivery system with controllable loading and releasing and thus help maintain good health, particularly targeting neurological diseases. This project has also involved fundamental research into the nanomaterial science, surface chemistry, cell biochemistry and neuron sciences. Successful completion of the project will contribute to the development of advanced materials helping Australia advance and build the industrial competitiveness. Through this project highly skilled researchers will be well trained. Read moreRead less
Special Research Initiatives - Grant ID: SR0354656
Funder
Australian Research Council
Funding Amount
$20,000.00
Summary
Particulate Science and Technology Network. Particulate Science and Technology (PST) is a rapidly developing interdisciplinary research field concerned with particle-related phenomena at different time and length scales and represents a very significant research and development effort in Australia for many years. This network is formed by linking the world-recognized research centres/groups with different expertise. Its aim is to provide greater collaboration among the Australian and overseas re ....Particulate Science and Technology Network. Particulate Science and Technology (PST) is a rapidly developing interdisciplinary research field concerned with particle-related phenomena at different time and length scales and represents a very significant research and development effort in Australia for many years. This network is formed by linking the world-recognized research centres/groups with different expertise. Its aim is to provide greater collaboration among the Australian and overseas researchers and enhance the scale and focus of particulate research. It will help develop and maintain Australia's leading position in PST, generating massive research outcomes and training that can lead to improvement in resource, energy, process and allied industries.Read moreRead less