Risk and Reliability in Stochastic Optimisation and Equilibrium. This project seeks to develop theory and methodology in optimisation which take advantage of recent progress in understanding and treating risk in decision making. Problems of optimisation in the face of uncertainty must confront the risk inherent in having to make reliable decisions before knowing the outcomes of crucial random variables on which costs and constraints may depend. Recent theoretical developments, featuring ‘measure ....Risk and Reliability in Stochastic Optimisation and Equilibrium. This project seeks to develop theory and methodology in optimisation which take advantage of recent progress in understanding and treating risk in decision making. Problems of optimisation in the face of uncertainty must confront the risk inherent in having to make reliable decisions before knowing the outcomes of crucial random variables on which costs and constraints may depend. Recent theoretical developments, featuring ‘measures of risk’ beyond just-expected values and quantiles offer hope of major new advances. This project aims to achieve such advances not only in optimisation but also in models of equilibrium that likewise have to deal with uncertainty. Extending current theory and methodology to such multi-stage stochastic models is a challenge. Besides taking up this challenge for its own sake, a major goal of this research will be to use the results in solution algorithms.Read moreRead less
Improving risk management based on short-term stochastic forecast for financial decisions. The project targets the problems of strategy selection in the framework of mathematical finance. The aim is to find ways to reduce the impact of forecast errors in the presence of uncertainty. Related forecasting algorithms and solutions of optimization problems will be obtained.
Determining features that separate groups of protein sequences. This project aims to develop mathematical approaches for determining features that distinguish one group of proteins from another, based on their amino acid sequences. The groups of sequences will reflect different outcomes, so that identifying the fundamental features can result in targeted interventions against the poorer outcome. A simple comparison at each position or of known features can fail to determine robust differentiator ....Determining features that separate groups of protein sequences. This project aims to develop mathematical approaches for determining features that distinguish one group of proteins from another, based on their amino acid sequences. The groups of sequences will reflect different outcomes, so that identifying the fundamental features can result in targeted interventions against the poorer outcome. A simple comparison at each position or of known features can fail to determine robust differentiators and so more complex methods are required. The project will, for example, help identify HIV vaccine targets by comparing early HIV transmission sequences from those in chronic infection. The methods will be applicable to viral proteins where high mutation rates make this task even more complex.Read moreRead less
A unified approach to the design of minimum length networks. This project aims to develop a new approach to designing minimum length interconnection networks by analysing their geometric structure. These networks form the basis of communication, power and transport systems. Optimising the design of such networks is a mathematically challenging problem of high computational complexity. This project will use an innovative method based on a relationship between the geometry of networks and a type o ....A unified approach to the design of minimum length networks. This project aims to develop a new approach to designing minimum length interconnection networks by analysing their geometric structure. These networks form the basis of communication, power and transport systems. Optimising the design of such networks is a mathematically challenging problem of high computational complexity. This project will use an innovative method based on a relationship between the geometry of networks and a type of partitioning of the plane called an oriented Voronoi diagram. The outcome will be efficient new algorithms for designing physical networks, which, in practice, will ultimately lead to a reduction in network infrastructure costs for industries in Australia.
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Operations research without convexity. Operations Research (OR) is one of the most applicable areas of mathematics and of importance for the future of technologically advanced Australia. However, applications of OR often require convexity. This is a serious limitation. A new approach, monotonic analysis, which is applicable to a broad class of nonconvex problems, was given birth by the CI. Promising results have been obtained and leading researchers around the world (including the Presidents ....Operations research without convexity. Operations Research (OR) is one of the most applicable areas of mathematics and of importance for the future of technologically advanced Australia. However, applications of OR often require convexity. This is a serious limitation. A new approach, monotonic analysis, which is applicable to a broad class of nonconvex problems, was given birth by the CI. Promising results have been obtained and leading researchers around the world (including the Presidents of the Canadian Mathematical and French Applied Mathematics Societies) are keen to work with the CI developing this topic. This project both cements and extends world leadership in this field.Read moreRead less
Maximizing Dimensional Efficiency With Minimal Cardinality Pattern Combinations. Making optimal use of dimensional capacity is often fundamental to the efficiency of processes in science and industry. Many important applications use combinations of patterns to achieve this. For example, in paper and in steel manufacturing, reels are divided lengthwise into cutting patterns, combined so as to minimize waste. In medicine, radiation patterns are combined to effectively treat cancerous tumours. ....Maximizing Dimensional Efficiency With Minimal Cardinality Pattern Combinations. Making optimal use of dimensional capacity is often fundamental to the efficiency of processes in science and industry. Many important applications use combinations of patterns to achieve this. For example, in paper and in steel manufacturing, reels are divided lengthwise into cutting patterns, combined so as to minimize waste. In medicine, radiation patterns are combined to effectively treat cancerous tumours. By addressing the common mathematical structure underlying pattern combination, this project will account for a hitherto neglected critical factor - the solution cardinality - making fully optimized solutions available for the first time to many applications in science and industry.Read moreRead less
HYBRID METHODS FOR SOLVING LARGE-SCALE OPTIMISATION PROBLEMS. Mathematical modelling and optimisation plays a crucial role in the advancement of modern business, science and technology. A significant benefit of this project is the development of a range of powerful computational tools for improving the productivity of Australian industry, including: agriculture; communications; defence; manufacturing; mining and petroleum; transport and logistics. These tools will be built upon advances in the f ....HYBRID METHODS FOR SOLVING LARGE-SCALE OPTIMISATION PROBLEMS. Mathematical modelling and optimisation plays a crucial role in the advancement of modern business, science and technology. A significant benefit of this project is the development of a range of powerful computational tools for improving the productivity of Australian industry, including: agriculture; communications; defence; manufacturing; mining and petroleum; transport and logistics. These tools will be built upon advances in the fundamental theory developed by the research team. The resulting high quality publications and associated algorithms will greatly enhance Australia's international scientific reputation and provide Australian industry with new cutting-edge optimisation technology.Read moreRead less
Robust methods for hard optimization problems. Highly advanced industrial and information-based societies depend on complex systems that underpin their infrastructure and technologies. Mathematical modelling and optimization techniques are most frequently deployed for the development and refinement of these systems. This project focuses on an important class of difficult optimization problems that arise in many applications. A significant benefit of this project is the development of a number of ....Robust methods for hard optimization problems. Highly advanced industrial and information-based societies depend on complex systems that underpin their infrastructure and technologies. Mathematical modelling and optimization techniques are most frequently deployed for the development and refinement of these systems. This project focuses on an important class of difficult optimization problems that arise in many applications. A significant benefit of this project is the development of a number of robust methods for these hard optimization problems. These methods will be built upon advances in the fundamental theory developed by the research team. The resulting high quality publications and associated algorithms will greatly enhance Australia's international scientific reputation.Read moreRead less
Faster, cheaper, better: mathematical advances for improved design and scheduling of robotic instrumentation. This project extends previous research addressing mathematical challenges in the optimal design and scheduling of robotic instrumentation. The Partner Organisation manufactures instruments for cancer diagnostics, and designs instruments that need to produce rapid, high-quality results, at a reasonable cost in a competitive market. It is intended that powerful new scheduling algorithms wi ....Faster, cheaper, better: mathematical advances for improved design and scheduling of robotic instrumentation. This project extends previous research addressing mathematical challenges in the optimal design and scheduling of robotic instrumentation. The Partner Organisation manufactures instruments for cancer diagnostics, and designs instruments that need to produce rapid, high-quality results, at a reasonable cost in a competitive market. It is intended that powerful new scheduling algorithms will be devised to handle their complex problem, which is more challenging than standard problems. The developed methodologies aim to reduce the product development cycle and boost the competitiveness of Australian manufacturers. In addition, new theoretical and algorithmic contributions aim to enable improved scheduling in other application areas.Read moreRead less
An integrated mathematical approach to synchronise and optimise hospital operations. This project aims to develop an integrated mathematical approach to synchronise and optimise patient scheduling systems of different departments to ensure that the hospital’s assets and related resources are used efficiently. The project’s aim is to investigate patient flow, process delay, and the interaction and inter-dependence of departments within the hospital to reduce access block (bottleneck) and subseque ....An integrated mathematical approach to synchronise and optimise hospital operations. This project aims to develop an integrated mathematical approach to synchronise and optimise patient scheduling systems of different departments to ensure that the hospital’s assets and related resources are used efficiently. The project’s aim is to investigate patient flow, process delay, and the interaction and inter-dependence of departments within the hospital to reduce access block (bottleneck) and subsequent overcrowding. This project aims to smooth the running of the hospital, improve the efficiency of patient throughput, reduce waiting times, and revolutionise hospital planning and scheduling.Read moreRead less