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Inequality and economic growth. This project aims to identify forces driving inequality. Piketty’s influential book, Capital in the 21st Century, stimulated research on inequality to address the increased public concern about inequality and its side-effects such as reduced growth. Piketty proposes three laws that explain and predict inequality paths over time, but there is no empirical evidence or theoretical foundations for these laws. This project will examine Piketty’s laws and investigate fa ....Inequality and economic growth. This project aims to identify forces driving inequality. Piketty’s influential book, Capital in the 21st Century, stimulated research on inequality to address the increased public concern about inequality and its side-effects such as reduced growth. Piketty proposes three laws that explain and predict inequality paths over time, but there is no empirical evidence or theoretical foundations for these laws. This project will examine Piketty’s laws and investigate factors that shape inequality and its relation to growth. This knowledge should enable Australian governments to reduce inequality and benefit economic growth, thereby reducing disadvantage and building stronger, more resilient communities.Read moreRead less
Government, Institutions and Economic Activity: A Long Term Analysis. Using national and regional data for 30 to 50 countries over multiple centuries, this project will examine the effects of itemised government expenditure and revenue on productivity, investment, saving, labour force participation and research and development. The results are expected to shed light on the macroeconomic effects of different revenue and spending categories (education, transfers, and so on). In addition, the proje ....Government, Institutions and Economic Activity: A Long Term Analysis. Using national and regional data for 30 to 50 countries over multiple centuries, this project will examine the effects of itemised government expenditure and revenue on productivity, investment, saving, labour force participation and research and development. The results are expected to shed light on the macroeconomic effects of different revenue and spending categories (education, transfers, and so on). In addition, the project aims to determine which factors have been responsible for the increase of government size over the past two centuries. The results aim to further reveal which government revenue and expenditure items are most conducive to economic welfare and growth.Read moreRead less
Growth, Trade, and Economic Development in Asia. Future growth in Asia has strong implications for growth, relative wages, skill levels, human capital accumulation and trade in Australia. This project seeks to gain insight into whether the high economic growth rates experienced in Asia will continue into the future and whether low income Asian countries will take off in the future. This information will be used to simulate future demand for skills, relative wages, trade and the incentives to inv ....Growth, Trade, and Economic Development in Asia. Future growth in Asia has strong implications for growth, relative wages, skill levels, human capital accumulation and trade in Australia. This project seeks to gain insight into whether the high economic growth rates experienced in Asia will continue into the future and whether low income Asian countries will take off in the future. This information will be used to simulate future demand for skills, relative wages, trade and the incentives to invest in Australia and give insight into the effects of various policies in Australia on educational decision, skill composition, relative wages, trade and growth.Read moreRead less
Birth Weight, Adult Weight And Podocyte Depletion.
Funder
National Health and Medical Research Council
Funding Amount
$796,252.00
Summary
A major role of our kidneys is to filter our blood. A key cell type in our kidney filters is an octopus-shaped cell known as the podocyte. If we are not born with enough podocytes, or if the filters grow too large after birth due for example to excessive weight gain, the podocytes cannot adequately filter the blood, and this can lead to kidney disease. We will measure podocyte endowment at birth, and assess the effects of weight gain and loss after birth on podocyte features and kidney health.
The Molecular Basis For Target Selection In The Central Nervous System By Sensory Axons
Funder
National Health and Medical Research Council
Funding Amount
$251,325.00
Summary
The normal function of the brain depends upon the specific connections that nerve cells make with each other. These connections are set up in the developing embryo when nerve cells send out long processes - axons - which grow towards their synaptic targets. How axons select their correct targets from amongst the millions of alternatives in the developing brain is unknown. A better understanding of this problem will help us develop therapies to assist regenerating axons re-establish correct conne ....The normal function of the brain depends upon the specific connections that nerve cells make with each other. These connections are set up in the developing embryo when nerve cells send out long processes - axons - which grow towards their synaptic targets. How axons select their correct targets from amongst the millions of alternatives in the developing brain is unknown. A better understanding of this problem will help us develop therapies to assist regenerating axons re-establish correct connections following injury to the brain or spinal cord. We propose to use a simple model system, the embryo of the fruitfly Drosophila, to find molecules that are involved in this process of neuron target recognition - ' axon targeting' molecules - and to study how they work. Drosophila can be genetically manipulated in ways not possible in higher animals. Furthermore the simplicity of its nervous system means that we can determine the connections of individual nerve cells with a high degree of precision. In the first part of our project, we will examine Drosophila embryos that carry mutations in genes suspected to code for targeting molecules. We will stain individual sensory nerve cells in these embryos with dyes to reveal the anatomy of their axons in the brain. If sensory axons terminate abnormally in the brain of a given mutant, the affected gene is likely to code for an axon targeting molecule. In the second part of the study, we will investigate the functions of candidate axon targeting molecules using two approaches. Firstly, we will seek to determine whether the molecule acts in the sensory axons or in their target cells. Secondly, we will use time-lapse microscopy to study how the homing behaviour of the sensory axons is affected in mutant embryos. The results of these studies will lead us closer to an answer to the question: How do axons recognise their specific target cells in the brain?Read moreRead less
Do Exposures Before Conception Influence The Risk Of Asthma In Offspring?
Funder
National Health and Medical Research Council
Funding Amount
$688,586.00
Summary
Asthma and poor lung function are major causes of public health issues. Emerging evidence suggests adverse exposures even before the conception of a child may cause these conditions. The proposed project is part of an international study across generations to identify these factors. This study will provide novel evidence to guide interventions and identify studies to advance this area further. These original findings will be of great importance both nationally and internationally.
Applications-oriented elucidation of germination triggers for Emu Bush seed. The project aims to determine the environmental and genetic mechanisms that currently limit seed germination in Emu Bush (Eremophila) species. The anticipated project outcomes aim to develop new technologies for efficient and mass production of Emu Bush seedlings. The outcomes will improve land restoration by increasing plant diversity and reducing establishment costs, and will also provide the nursery industry with nov ....Applications-oriented elucidation of germination triggers for Emu Bush seed. The project aims to determine the environmental and genetic mechanisms that currently limit seed germination in Emu Bush (Eremophila) species. The anticipated project outcomes aim to develop new technologies for efficient and mass production of Emu Bush seedlings. The outcomes will improve land restoration by increasing plant diversity and reducing establishment costs, and will also provide the nursery industry with novel products for home gardens. The intended project benefits are to increase the diversity of Australian native plants used for restoration and ornamental purposes and to promote the conservation of species in this plant family and its genetic diversity.Read moreRead less
Climate Change, Industrial Structure and the Knowledge Economy: Key Issues for an Effective Response on Greenhouse Gases. The objectives of this project are to undertake a major, long term study of the impact of global structural change on greenhouse gas emissions and on climate change, and to develop a detailed knowledge base concerning trade in embodied emissions. It is hoped that the knowledge generated will both inform global responses to this vital problem and contribute to the continuing d ....Climate Change, Industrial Structure and the Knowledge Economy: Key Issues for an Effective Response on Greenhouse Gases. The objectives of this project are to undertake a major, long term study of the impact of global structural change on greenhouse gas emissions and on climate change, and to develop a detailed knowledge base concerning trade in embodied emissions. It is hoped that the knowledge generated will both inform global responses to this vital problem and contribute to the continuing development of effective responses within Australia. The output - a book and many papers - will be directed in part to contribute to the IPCC's Fourth Assessment Report.Read moreRead less
The econometrics of gravity models of trade: a re-assessment. This research will lead a much greater understanding of the empirical determinants of trade flows between countries. This project will apply cutting-edge data econometric techniques to the popular Gravity model of international trade flows. These more appropriate techniques will shed more light on some previous puzzling findings, such that regional trade agreements had little, or no, affect on trade.
A Randomised Controlled Trial Of Interventional Versus Conservative Treatment Of Primary Spontaneous Pneumothorax
Funder
National Health and Medical Research Council
Funding Amount
$412,315.00
Summary
Primary spontaneous pneumothorax (PSP) is a collapsed lung that occurs in otherwise healthy people without underlying lung disease. Current standard treatment is to insert a chest drain into the chest to remove the air around the collapsed lung so that the lung re-inflates rapidly ("interventional treatment"). We will determine whether doing nothing, i.e. letting the lung re-inflate slowly on its own over several weeks ("conservative treatment"), is just as good or even better for patients.