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Birth Weight, Adult Weight And Podocyte Depletion.
Funder
National Health and Medical Research Council
Funding Amount
$796,252.00
Summary
A major role of our kidneys is to filter our blood. A key cell type in our kidney filters is an octopus-shaped cell known as the podocyte. If we are not born with enough podocytes, or if the filters grow too large after birth due for example to excessive weight gain, the podocytes cannot adequately filter the blood, and this can lead to kidney disease. We will measure podocyte endowment at birth, and assess the effects of weight gain and loss after birth on podocyte features and kidney health.
Prediction and control of fluid-structure interactions. Fluid-flows create a pressure that can deform the surface of a structure or cause it to vibrate; an extreme example is the fluttering of a flag. Flow-induced vibration of the external panels of vehicles causes damage, noise and can adversely affect performance. This project will develop a wholly new approach for the analysis of these interactions. The versatility and completeness of the approach permits a step-change in the design of panels ....Prediction and control of fluid-structure interactions. Fluid-flows create a pressure that can deform the surface of a structure or cause it to vibrate; an extreme example is the fluttering of a flag. Flow-induced vibration of the external panels of vehicles causes damage, noise and can adversely affect performance. This project will develop a wholly new approach for the analysis of these interactions. The versatility and completeness of the approach permits a step-change in the design of panels, reducing material and manufacturing costs without compromise to safety and performance - an immense benefit for the myriad engineered products or structures that feature flow over a deformable surface. Read moreRead less
Taming turbulence: Hydrodynamic stability and flow-structure interaction using grid-free computation. Turbulence is characterized as seemingly disordered fluctuations that impede the progress of an object through a fluid by creating increased frictional or drag forces. Using a new type of fluid-flow simulation, this project will generate advanced understanding of turbulence in the flow over the surface of a vehicle, be it a ship, car, aircraft or within a pipe, with the technological objective o ....Taming turbulence: Hydrodynamic stability and flow-structure interaction using grid-free computation. Turbulence is characterized as seemingly disordered fluctuations that impede the progress of an object through a fluid by creating increased frictional or drag forces. Using a new type of fluid-flow simulation, this project will generate advanced understanding of turbulence in the flow over the surface of a vehicle, be it a ship, car, aircraft or within a pipe, with the technological objective of reducing drag by adhering a compliant skin to the surface. While the correct choice of compliance relies upon understanding very complex flow-structure dynamics, the resulting technology is simple, robust and has low capital and maintenance costs. Clearly, drag reduction reduces fuel costs and lower fuel consumption is environmentally beneficial. Read moreRead less
Assessing the determinants and consequences of safety climate in the maritime industry. This project will examine the predictors and outcomes of safety climate in the Australian maritime industry. Findings from this project will be used to improve safety policies, regulations and practices that aim to minimise the number of accidents and incidents in Australian waters.
The Transmission Of Perinatal Maternal Mental Health To Preschool Emotional Disorders: Examining Pathways And Intervention Points In The MPEWS Study
Funder
National Health and Medical Research Council
Funding Amount
$970,795.00
Summary
While it is known that depression, anxiety and stress in pregnancy increase the risk for poorer child mental health, what is unknown is the key pathways and intervention points to prevent this transmission of risk. This study will examine potential mechanisms and intervention points through a selected cohort study: Mercy Pregnancy and Emotional Wellbeing Study. This study follows 500 women and their children from first trimester in pregnancy until the children are 3 years of age.
DEVELOPMENT OF NEW NONLINEAR CONTROLLERS FOR TRAJECTORY TRACKING AND PATH-FOLLOWING OF UNDERACTUATED OCEAN VEHICLES. Trajectory tracking control and path-following of underactuated ocean vehicles are not only of theoretical challenging but also important practice. This project is firstly to develop methodologies to design full-state feedback controllers to force the underactuated ocean vehicles including surface ships and underwater vehicles with off-diagonal terms in their system matrices to tr ....DEVELOPMENT OF NEW NONLINEAR CONTROLLERS FOR TRAJECTORY TRACKING AND PATH-FOLLOWING OF UNDERACTUATED OCEAN VEHICLES. Trajectory tracking control and path-following of underactuated ocean vehicles are not only of theoretical challenging but also important practice. This project is firstly to develop methodologies to design full-state feedback controllers to force the underactuated ocean vehicles including surface ships and underwater vehicles with off-diagonal terms in their system matrices to track reference trajectories generated by virtual vehicles, and to follow a predefined path with a desired forward speed. Secondly, we develop methods to design observers to estimate the unmeasured states (velocities) of the vehicles and incorporate with the full-state feedback controllers to have output-feedback observer-based controllers. Lastly, the proposed control design methods are extended to a certain class of underactuated mechanical systems.Read moreRead less
IMPACTS OF TRANSIT LED DEVELOPMENT IN A NEW RAIL CORRIDOR. Impacts of transit-oriented development (TOD) in precincts adjoining the new Perth-Mandurah railway will be addressed by longitudinal survey. Results of a revealed preference questionnaire about actual trips will be combined with a stated choice questionnaire. Aims are to quantify the effects of TOD on rail and car use and on daily activities, new railway services on the travel behaviour of households near new station precincts, differin ....IMPACTS OF TRANSIT LED DEVELOPMENT IN A NEW RAIL CORRIDOR. Impacts of transit-oriented development (TOD) in precincts adjoining the new Perth-Mandurah railway will be addressed by longitudinal survey. Results of a revealed preference questionnaire about actual trips will be combined with a stated choice questionnaire. Aims are to quantify the effects of TOD on rail and car use and on daily activities, new railway services on the travel behaviour of households near new station precincts, differing accessibility of station precincts on household travel patterns, improved accessibility on economic activity and employment. Replacement of car-trips by walking and cycling, changes in shopping & leisure activities & the effect of trip-chaining on number of trips are of particular interest.Read moreRead less
Analysis and modeling of driving patterns for limited-range electric vehicles. The electrification of the personal transport sector seems to be only a matter of time. It is important to study and model the effects of this sector now, in order to recommend decision makers on issues like standardization and infrastructure planning. Understanding and being able to predict EV driving and charging patterns will allow us to provide planning assistance for:
· Effects of day-time dependent energy pri ....Analysis and modeling of driving patterns for limited-range electric vehicles. The electrification of the personal transport sector seems to be only a matter of time. It is important to study and model the effects of this sector now, in order to recommend decision makers on issues like standardization and infrastructure planning. Understanding and being able to predict EV driving and charging patterns will allow us to provide planning assistance for:
· Effects of day-time dependent energy pricing structure on EV charging behavior
· Optimal energy pricing to encourage off-peak charging
· Optimal number and location of EV charging stations
· Expected uptake of PHEV/EVs depending on petrol, electricity and conversion cost
· Expected additional energy demand for EVs and PHEVs with day-time energy usage pattern
Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE240100118
Funder
Australian Research Council
Funding Amount
$500,000.00
Summary
The National Cycling Data and Analysis Platform (NCDAP) . A National Cycling Data and Analytics Platform to collect, integrate and communicate new and historic data on cycling infrastructure, attitudes, and behaviours. This project will address the significant issue of data fragmentation, pilot a national cycling survey, and develop a cycling toolkit to allow exploring and testing various cycling infrastructure scenarios. The platform will provide an open access e-Infrastructure to enable tracki ....The National Cycling Data and Analysis Platform (NCDAP) . A National Cycling Data and Analytics Platform to collect, integrate and communicate new and historic data on cycling infrastructure, attitudes, and behaviours. This project will address the significant issue of data fragmentation, pilot a national cycling survey, and develop a cycling toolkit to allow exploring and testing various cycling infrastructure scenarios. The platform will provide an open access e-Infrastructure to enable tracking social and cultural changes that influence transport choices, create effective behaviour change programs and prioritise cycling infrastructure investment. This project will contribute to healthier lifestyles, reduced traffic congestion and emissions and energy efficiency of Australia’s transport sector.Read moreRead less
Reducing The Effects Of Antenatal Alcohol On Child Health (REAACH)
Funder
National Health and Medical Research Council
Funding Amount
$2,497,397.00
Summary
Use of alcohol in pregnancy can affect the developing baby and cause Fetal Alcohol Spectrum Disorders (FASD). Children with FASD have lifelong brain injury that can lead to poor school performance, poor mental health and trouble with the law. This CRE builds on our strong background in research and community engagement to improve FASD prevention, diagnosis and treatment across Australia.