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Birth Weight, Adult Weight And Podocyte Depletion.
Funder
National Health and Medical Research Council
Funding Amount
$796,252.00
Summary
A major role of our kidneys is to filter our blood. A key cell type in our kidney filters is an octopus-shaped cell known as the podocyte. If we are not born with enough podocytes, or if the filters grow too large after birth due for example to excessive weight gain, the podocytes cannot adequately filter the blood, and this can lead to kidney disease. We will measure podocyte endowment at birth, and assess the effects of weight gain and loss after birth on podocyte features and kidney health.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100104
Funder
Australian Research Council
Funding Amount
$400,000.00
Summary
Capability for the fabrication and characterisation of mid-infrared photonic materials. The proposed facility will support the development of new glass materials suitable for transmitting and generating light in the mid-infrared spectral region. This research will allow Australia to lead the world in developing new technologies that make use of the mid-infrared region of the electromagnetic spectrum. Particular applications that will flow from this research include the development of new optical ....Capability for the fabrication and characterisation of mid-infrared photonic materials. The proposed facility will support the development of new glass materials suitable for transmitting and generating light in the mid-infrared spectral region. This research will allow Australia to lead the world in developing new technologies that make use of the mid-infrared region of the electromagnetic spectrum. Particular applications that will flow from this research include the development of new optical fibre-based laser sources for defence and surgery, new technologies for detecting and treating cancer, and other in-vivo detection methods.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE180100203
Funder
Australian Research Council
Funding Amount
$956,700.00
Summary
Novel diagnostics capabilities in reacting, particle-laden flows. This project aims to establish innovative capabilities for advanced diagnostics techniques to be applied in reacting, particle-laden flows over a range of pressures. The complementary measurements are expected to provide an unprecedented understanding of the dynamics of liquid fragments and solid particles in flames. The resulting data, and improved knowledge, will set the framework for more effective predictive methods that assis ....Novel diagnostics capabilities in reacting, particle-laden flows. This project aims to establish innovative capabilities for advanced diagnostics techniques to be applied in reacting, particle-laden flows over a range of pressures. The complementary measurements are expected to provide an unprecedented understanding of the dynamics of liquid fragments and solid particles in flames. The resulting data, and improved knowledge, will set the framework for more effective predictive methods that assist in the design of cleaner and efficient processes that benefit a range of applications, from engine design to the generation of new fuels, and the flame synthesis of novel materials.Read moreRead less
Resolving the mechanics of turbulent noise production. This project aims to dramatically develop our capacity to quieten modern transport, energy and defence technologies through a better understanding of how fluid turbulence creates sound. The outcome of the project will be a quieter modern environment leading to improved public health, an improved environment and a more secure nation.
Controlling the organisation of matter using vortex fluidics. Vortex fluidic devices will be developed and used to construct functional complex molecules and materials, and probe the structure of self assembled systems. The scalable processing will be assessed for application in advanced materials production, the chemical industry and in developing complex molecules for drug discovery.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE140100009
Funder
Australian Research Council
Funding Amount
$1,064,000.00
Summary
Ultra-high resolution magnetic resonance imaging (MRI) system for physical applications. Ultra-high resolution magnetic resonance imaging (MRI) system for physical applications: Ultra-high field magnetic resonance imaging provides unique high contrast images at previously inaccessible levels of resolution (<0.1mm). It non-invasively provides unprecedented information on chemical and biochemical processes including functional biological mechanisms. This infrastructure will be the focal point for ....Ultra-high resolution magnetic resonance imaging (MRI) system for physical applications. Ultra-high resolution magnetic resonance imaging (MRI) system for physical applications: Ultra-high field magnetic resonance imaging provides unique high contrast images at previously inaccessible levels of resolution (<0.1mm). It non-invasively provides unprecedented information on chemical and biochemical processes including functional biological mechanisms. This infrastructure will be the focal point for more than 100 academics and HDR students. It will take Australia to the forefront of magnetic resonance imaging capability as well as providing unique insights into diffusion and electrophoretic problems central to designing next generation energy storage. Outcomes will range from agricultural advances, higher performing batteries, and more effective cancer treatments as well advancing Australia's fundamental scientific capabilities.Read moreRead less
A Novel Inline High-Efficiency Motor/Pump System. Around 19% of the world’s and 30% of the Australia’s electric energy is consumed by pump technologies. Significant energy savings are possible if the major components of pump systems, including inverter, motor and pump, operate at their maximum possible efficiency under varying loads. A novel pump design in this project accommodates integrated electronics in a submersible housing. A seal-less design helps mitigate several aspects of pump failure ....A Novel Inline High-Efficiency Motor/Pump System. Around 19% of the world’s and 30% of the Australia’s electric energy is consumed by pump technologies. Significant energy savings are possible if the major components of pump systems, including inverter, motor and pump, operate at their maximum possible efficiency under varying loads. A novel pump design in this project accommodates integrated electronics in a submersible housing. A seal-less design helps mitigate several aspects of pump failure and its in-line structure reduces assembly cost. Accurately measured efficiency maps will be utilised to demonstrate the non-linear relationship between motor and pump quantities as well as developing models for indirectly estimating feedback quantities and achieving the highest system efficiency.Read moreRead less
Airborne ultrafine particles in Australian cities. There is an acute deficiency of knowledge in Australia on urban airborne ultrafine particles, originating from transport and other anthropogenic sources, which pose significant health and environmental risks. The aim of this project is to address this deficiency by an extensive multi-city, cross-disciplinary study using state of the art instrumentation and data analytic techniques. The outcome will be an in depth, quantitative insight into the c ....Airborne ultrafine particles in Australian cities. There is an acute deficiency of knowledge in Australia on urban airborne ultrafine particles, originating from transport and other anthropogenic sources, which pose significant health and environmental risks. The aim of this project is to address this deficiency by an extensive multi-city, cross-disciplinary study using state of the art instrumentation and data analytic techniques. The outcome will be an in depth, quantitative insight into the characteristics of the particles, their sources and spatial and temporal variation across different urban areas and time scales. Further, the impacts of changing fuels, vehicle technologies, and climate on future trends of the particles will be elucidated.Read moreRead less
Multiliteracies for addressing disadvantage in senior school science. Multiliteracies for addressing disadvantage in senior school science. This project aims to develop discipline-specific pedagogies in senior physics, chemistry and biology to improve disadvantaged students’ engagement and achievement. Many students from disadvantaged backgrounds fail to develop the linguistic precision and symbolic representational dexterity needed to comprehend and communicate senior school science concepts. T ....Multiliteracies for addressing disadvantage in senior school science. Multiliteracies for addressing disadvantage in senior school science. This project aims to develop discipline-specific pedagogies in senior physics, chemistry and biology to improve disadvantaged students’ engagement and achievement. Many students from disadvantaged backgrounds fail to develop the linguistic precision and symbolic representational dexterity needed to comprehend and communicate senior school science concepts. These pedagogies will ‘infuse’ multiliteracies in senior school science to improve access to science-based pathways for these students, and enable them to understand progressively more complex scientific concepts and demonstrate this in examinations. This project is expected to improve student retention, arrest declining enrolments in senior school science, and increase young people working in science.Read moreRead less
Engaging Students during the Early Years of Secondary School. This project aims to design, test and share sustainable strategies to support teachers and enable students from low socioeconomic communities to achieve success. The greatest decreases in students’ interest and effort occur when they transition into secondary school, with students from low socioeconomic communities at greatest risk of disengagement. What can teachers do to engage their students during this key life transition? This pr ....Engaging Students during the Early Years of Secondary School. This project aims to design, test and share sustainable strategies to support teachers and enable students from low socioeconomic communities to achieve success. The greatest decreases in students’ interest and effort occur when they transition into secondary school, with students from low socioeconomic communities at greatest risk of disengagement. What can teachers do to engage their students during this key life transition? This project plans to identify teacher behaviours that motivate students in their first year at secondary school. Using an experimental design with a representative sample of 150 teachers and 1500 students in low socioeconomic areas across three states, the project plans to test whether an online professional learning program for teachers can improve student engagement and achievement. This cost-effective and scalable intervention is designed for widespread dissemination to Australian teachers.Read moreRead less