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Understanding The Acute And Cumulative Metabolic Effects Of Prolonged Sitting In Adults
Funder
National Health and Medical Research Council
Funding Amount
$416,597.00
Summary
Sedentary behaviour (sitting time) has been linked to an increased risk of chronic illnesses, including type 2 diabetes and obesity, but recent evidence suggests that light-intensity activity (non-exercise activities of daily living) is associated with reduced risk. These studies will examine whether breaking up sitting time with frequent short periods of activity can overcome the negative effects of prolonged sitting on blood glucose and blood fats in overweight older adults.
Signaling Pathways To Enhance Potency Of AMPK-targeting Drugs
Funder
National Health and Medical Research Council
Funding Amount
$661,966.00
Summary
Sedentary lifestyles and consumption of high energy foods has led to epidemics of obesity-related metabolic diseases that place enormous financial and medical burden on the Australian economy. An attractive drug target to treat these diseases is AMP-activated protein kinase (AMPK) which functions as both a cellular fuel gauge and co-ordinator of whole-body metabolism. Our goal is to improve AMPK drug potency by identifying novel processes that sensitize AMPK to drugs.
Mechanism of AMPK activation by drugs and metabolites. This project aims to identify the molecular basis of activation mechanisms in the AMP-activated protein kinase (AMPK), an enzyme that regulates burning and storage of fuels such as fat and sugars, autophagy and controls appetite and energy expenditure. This project expects to provide insights into how energy metabolism and physiological functions are linked.
Peopling educational policy: realising the new Australian English and mathematics curricula. Implementation of Australian curricula in English and mathematics provides an opportunity for school systems to re-examine practice. This project will identify resources and teacher learning opportunities needed to facilitate implementation of these curricula and use findings to develop interventions identified as likely to optimise implementation.
Using mathematics to solve real world problems. This project aims to identify, apply and refine teaching approaches that help secondary students learn mathematical modelling, using mathematics to solve real world problems. The study will investigate the mathematical, cognitive, social and environmental factors that "enable" Year 10/11 students to develop mathematical representations of a real world problem. This project expects to generate theoretical and practical insights into how these enable ....Using mathematics to solve real world problems. This project aims to identify, apply and refine teaching approaches that help secondary students learn mathematical modelling, using mathematics to solve real world problems. The study will investigate the mathematical, cognitive, social and environmental factors that "enable" Year 10/11 students to develop mathematical representations of a real world problem. This project expects to generate theoretical and practical insights into how these enablers promote successful modelling, tasks that support students' development as modellers, and effective teaching approaches that promote student capability and interest in mathematics.Read moreRead less
Investigating the relationship between teacher expectations, student persistence and the learning of mathematics. There is a culture in many classrooms in which teachers are encouraged by students to pose easy tasks. The project will explore what is needed to encourage students to embrace challenges and to persist even when tasks are difficult. The outcome will be enhanced mathematics learning and improved student confidence.
Improving student outcomes: coaching teachers in the power of feedback. This project aims to investigate how student outcomes can be augmented through coaching teachers in effective feedback practice. The project addresses a critical problem of stagnating levels of student achievement in Australian schools with the innovative research design combining evidence-based, pedagogies of feedback, formative assessment and instructional coaching to improve teacher practice and ultimately raise student a ....Improving student outcomes: coaching teachers in the power of feedback. This project aims to investigate how student outcomes can be augmented through coaching teachers in effective feedback practice. The project addresses a critical problem of stagnating levels of student achievement in Australian schools with the innovative research design combining evidence-based, pedagogies of feedback, formative assessment and instructional coaching to improve teacher practice and ultimately raise student achievement levels. The project aims to guide policy implementation in pedagogy to raise the quality of teaching standards and to improve learning outcomes for Australian students. Ultimately, outcomes from the research will help close the gap for low achieving students, and challenge and extend those who may already be meeting required benchmarks. Read moreRead less
Out-of-field Teaching: Sustaining Quality Practices Across Subjects. Teaching out-of-field (teaching a subject without qualifications) is a rising concern internationally, and is linked to attrition, stress, and reduced student learning outcomes. With a comparatively high percentage of out-of-field teachers, Australia is exposed to significant social, economic and educational costs. Through the development of longitudinal case studies, this project investigates the changing landscape of teacher ....Out-of-field Teaching: Sustaining Quality Practices Across Subjects. Teaching out-of-field (teaching a subject without qualifications) is a rising concern internationally, and is linked to attrition, stress, and reduced student learning outcomes. With a comparatively high percentage of out-of-field teachers, Australia is exposed to significant social, economic and educational costs. Through the development of longitudinal case studies, this project investigates the changing landscape of teacher perceptions and practices over three years, within school institutional cultures relating to teacher assignment, support, and out-of-field mathematics and science teaching. Outcomes of the project will aim to inform the development of system and school policy and practice, in dealing with this internationally pervasive issue.Read moreRead less
Enhancing numeracy learning and teaching across the curriculum. Leaving school without an adequate level of numeracy has devastating consequences for young people's life chances. This project will implement a rich approach to numeracy across the curriculum in Years 3, 5, 7 and 9 with the aim of improving students' numeracy learning outcomes and teachers' confidence with and understanding of numeracy.
Globalising studies of the politics of history education: a comparative analysis of history national curriculum implementation in Russia and Australia. Internationally, history education has been, and continues to be, a highly controversial element in curriculum change. In that context, this project compares and analyses the processes involved in developing national history curricula in Russia (a former dictatorship) and in Australia (a liberal democracy).