Engineering the trafficking of nanoparticles within cells. This project aims to engineer responsive nanoparticles capable of trafficking efficiently within cells. The site of release of therapeutic cargo has importance for improving the efficacy of many treatments, for example vaccine delivery. Therefore fundamental understanding of how nanoparticle structure can be engineered to control cellular behaviour is necessary. The project will engineer new polymeric nanomaterials and investigate the im ....Engineering the trafficking of nanoparticles within cells. This project aims to engineer responsive nanoparticles capable of trafficking efficiently within cells. The site of release of therapeutic cargo has importance for improving the efficacy of many treatments, for example vaccine delivery. Therefore fundamental understanding of how nanoparticle structure can be engineered to control cellular behaviour is necessary. The project will engineer new polymeric nanomaterials and investigate the impact of their structure on biological properties. The benefits of this project will include new fundamental insights into improving nanoparticle design for vaccine delivery, as well as the expansion of Australia’s knowledge base in the area of biodegradable polymers.Read moreRead less
Pore Engineering of Chromatography Membranes for Bioseparation. Protein separation and purification is an essential unit operation in manufacturing processes of therapeutic proteins. The project aims to advance the practical applications of chromatography membrane, an emerging technology for protein separation and purification, by tailoring membrane pore geometry and surface functionality to achieve enhanced separation performance. The project expects to generate advanced knowledge and technique ....Pore Engineering of Chromatography Membranes for Bioseparation. Protein separation and purification is an essential unit operation in manufacturing processes of therapeutic proteins. The project aims to advance the practical applications of chromatography membrane, an emerging technology for protein separation and purification, by tailoring membrane pore geometry and surface functionality to achieve enhanced separation performance. The project expects to generate advanced knowledge and techniques in the fields of reactive polymer synthesis, functional membrane fabrication and application in bioseparation. The innovative membranes developed in the project are able to improve the production capacity of therapeutic protein manufacturing processes, providing significant economic benefits to Australia.Read moreRead less
Carbon Molecular Sieve Membranes for Organic Solvent Separation. Directly addressing the pressing challenge of organic solvent separation faced by numerous industries, the project aims to develop molecular sieve membranes with outstanding selectivity and solvent tolerance by constructing zeolite-carbon mixed matrix membrane via incorporating zeolite nanosheets into carbon materials. The project expects to generate advanced knowledge of nanosheet synthesis, membrane fabrication and selective mole ....Carbon Molecular Sieve Membranes for Organic Solvent Separation. Directly addressing the pressing challenge of organic solvent separation faced by numerous industries, the project aims to develop molecular sieve membranes with outstanding selectivity and solvent tolerance by constructing zeolite-carbon mixed matrix membrane via incorporating zeolite nanosheets into carbon materials. The project expects to generate advanced knowledge of nanosheet synthesis, membrane fabrication and selective molecule transport. The membranes developed in the project have great potentials for improving the production capacity and sustainability of Australian industries, e.g., pharmaceutical manufacturing, bioethanol production and petroleum refining, providing significant economic and environmental benefits to Australia.Read moreRead less
High value micron-sized particles from a novel antisolvent vapour spray drying system. Convective antisolvent precipitation is a novel route in producing particles from spray drying by adding an anti-solvent to the drying medium. This project will allow conventional spray dryers to produce more sophisticated ultrafine and encapsulated particles for use in food, pharmaceuticals and other high value applications.
Crystal engineering of membranes for chiral separation . This project addresses the urgent challenge of chiral separation in the manufacturing of pharmaceuticals and agrochemicals by creating a new class of membranes produced by engineering functionalised porous framework crystals. This project expects to generate new knowledge regarding how membrane chemistry and architecture can be used to achieve highly selective, fast chiral molecule transport. The expected outcomes of the project include ne ....Crystal engineering of membranes for chiral separation . This project addresses the urgent challenge of chiral separation in the manufacturing of pharmaceuticals and agrochemicals by creating a new class of membranes produced by engineering functionalised porous framework crystals. This project expects to generate new knowledge regarding how membrane chemistry and architecture can be used to achieve highly selective, fast chiral molecule transport. The expected outcomes of the project include new membrane compositions, design principles, fabrication techniques, and proof-of-concept production of scalable, high-performance composite membranes. This project should produce significant economic and environmental benefits in the development of advanced membranes, pharmaceuticals, and agrochemicals.Read moreRead less
Engineered control of polarisation rotation in ferroelectric bilayers. This project aims to develop interface engineered nanoscale ferroelectric thin films with functional properties suitable for integration. Bulk ferroelectrics form the core of traditional stand-alone electromechanical devices such as sensors, actuators and ultrasonic devices. Future applications need to be integrated into thin film form on semiconductor wafers, but the attachment to the wafer induces a mechanical constraint, w ....Engineered control of polarisation rotation in ferroelectric bilayers. This project aims to develop interface engineered nanoscale ferroelectric thin films with functional properties suitable for integration. Bulk ferroelectrics form the core of traditional stand-alone electromechanical devices such as sensors, actuators and ultrasonic devices. Future applications need to be integrated into thin film form on semiconductor wafers, but the attachment to the wafer induces a mechanical constraint, which dramatically suppresses the electromechanical response. This project aims to solve this problem by "polarisation rotation", achieved by layered stacking of thin film ferroelectrics. Engineered control of ferroelectric polarization rotation could be the pathway to modern electromechanical devices.Read moreRead less
Exploration of lead free ferroelectric crystals for transducer applications. This project aims to investigate lead free crystals, which are expected to possess high piezoelectric properties for medical imaging and underwater acoustics, as an alternative to toxic lead-based ferroelectrics which have been dominantly used in ultrasound transducers. The project will have significant impact on development of new lead-free ferroelectric crystals with desirable properties. This will benefit Australian ....Exploration of lead free ferroelectric crystals for transducer applications. This project aims to investigate lead free crystals, which are expected to possess high piezoelectric properties for medical imaging and underwater acoustics, as an alternative to toxic lead-based ferroelectrics which have been dominantly used in ultrasound transducers. The project will have significant impact on development of new lead-free ferroelectric crystals with desirable properties. This will benefit Australian industry by providing knowledge and technology of crystal growth, enabling advanced ultrasound transducers for medical imaging and underwater acoustic applications.Read moreRead less
Developing Multi-Scale Technologies for Two-Dimensional Metal Nanoparticle Superlattice Sheets. Nanoparticle superlattices refer to highly ordered nanoparticle arrays, which are a new class of crystalline materials with collective properties different from those of bulk phase crystals, isolated nanocrystals and even disordered nanocrystal assemblies. However nanoparticle superlattice is still in the embryonic stage of development due to the lack of multiscale technologies. This project aims to d ....Developing Multi-Scale Technologies for Two-Dimensional Metal Nanoparticle Superlattice Sheets. Nanoparticle superlattices refer to highly ordered nanoparticle arrays, which are a new class of crystalline materials with collective properties different from those of bulk phase crystals, isolated nanocrystals and even disordered nanocrystal assemblies. However nanoparticle superlattice is still in the embryonic stage of development due to the lack of multiscale technologies. This project aims to develop such important technologies to produce two-dimensional nanoparticle superlattice sheets for novel energy-harvesting devices. This will generate new knowledge and important patentable technologies for future energy industries, contributing to further advance Australian knowledge base and build a greener world.Read moreRead less
High performance durable perovskite solar cells for space applications . There has been a rapid growth in space exploration and experimentation fuelled by global support. Space hardware needs to be powered by a sustainable source of energy. The use of solar photovoltaics is the preferred choice. As we move into the era of 'commercial space', cost will become paramount necessitating the development of new cost effective photovoltaic technologies. Metal halide perovskite solar cells show the great ....High performance durable perovskite solar cells for space applications . There has been a rapid growth in space exploration and experimentation fuelled by global support. Space hardware needs to be powered by a sustainable source of energy. The use of solar photovoltaics is the preferred choice. As we move into the era of 'commercial space', cost will become paramount necessitating the development of new cost effective photovoltaic technologies. Metal halide perovskite solar cells show the greatest potential. They have a higher power to weight ratio and are significantly cheaper to be manufactured compared to incumbent space cells. This project aims to develop and demonstrate perovskite solar cells to achieve high areal power conversion efficiencies and long operating lifetimes withstanding space environment. Read moreRead less
Poly(dendrimer) organic light-emitting diodes. This project aims to develop ultrathin efficient emissive technologies based on low embedded energy organic light-emitting diodes (OLEDs). It will develop transformative OLEDs that can be used in displays and lighting, by creating semiconductor materials and diode architectures that optimise each step in light generation, from charge injection, transport and capture to light emission. The efficiency improvements made possible by OLED technology can ....Poly(dendrimer) organic light-emitting diodes. This project aims to develop ultrathin efficient emissive technologies based on low embedded energy organic light-emitting diodes (OLEDs). It will develop transformative OLEDs that can be used in displays and lighting, by creating semiconductor materials and diode architectures that optimise each step in light generation, from charge injection, transport and capture to light emission. The efficiency improvements made possible by OLED technology can reduce electricity consumption, carbon dioxide emissions, and the cost of living.Read moreRead less