Engineering the trafficking of nanoparticles within cells. This project aims to engineer responsive nanoparticles capable of trafficking efficiently within cells. The site of release of therapeutic cargo has importance for improving the efficacy of many treatments, for example vaccine delivery. Therefore fundamental understanding of how nanoparticle structure can be engineered to control cellular behaviour is necessary. The project will engineer new polymeric nanomaterials and investigate the im ....Engineering the trafficking of nanoparticles within cells. This project aims to engineer responsive nanoparticles capable of trafficking efficiently within cells. The site of release of therapeutic cargo has importance for improving the efficacy of many treatments, for example vaccine delivery. Therefore fundamental understanding of how nanoparticle structure can be engineered to control cellular behaviour is necessary. The project will engineer new polymeric nanomaterials and investigate the impact of their structure on biological properties. The benefits of this project will include new fundamental insights into improving nanoparticle design for vaccine delivery, as well as the expansion of Australia’s knowledge base in the area of biodegradable polymers.Read moreRead less
Crystal engineering of membranes for chiral separation . This project addresses the urgent challenge of chiral separation in the manufacturing of pharmaceuticals and agrochemicals by creating a new class of membranes produced by engineering functionalised porous framework crystals. This project expects to generate new knowledge regarding how membrane chemistry and architecture can be used to achieve highly selective, fast chiral molecule transport. The expected outcomes of the project include ne ....Crystal engineering of membranes for chiral separation . This project addresses the urgent challenge of chiral separation in the manufacturing of pharmaceuticals and agrochemicals by creating a new class of membranes produced by engineering functionalised porous framework crystals. This project expects to generate new knowledge regarding how membrane chemistry and architecture can be used to achieve highly selective, fast chiral molecule transport. The expected outcomes of the project include new membrane compositions, design principles, fabrication techniques, and proof-of-concept production of scalable, high-performance composite membranes. This project should produce significant economic and environmental benefits in the development of advanced membranes, pharmaceuticals, and agrochemicals.Read moreRead less
Understanding the interaction between wool fibre surface and ionic liquids. This project will advance the knowledge on wool surface/ionic liquid interaction, which has the potential to revolutionize the traditional and environmentally unfriendly wool shrinkage-proof treatment technology. This will have significant industry wide benefit for the multi-billion dollar animal fibre industry.
Biodegradable magnesium alloy scaffolds for bone tissue engineering. This project aims to develop a class of porous, biocompatible, biofunctional and biodegradable magnesium alloy scaffolds with designed pore architecture and mechanical properties mimicking those of natural bone for tissue engineering applications. These magnesium alloy scaffolds will be biocompatible, able to bear loads, and will be gradually replaced by natural bone. The outcomes are expected to benefit the ageing population a ....Biodegradable magnesium alloy scaffolds for bone tissue engineering. This project aims to develop a class of porous, biocompatible, biofunctional and biodegradable magnesium alloy scaffolds with designed pore architecture and mechanical properties mimicking those of natural bone for tissue engineering applications. These magnesium alloy scaffolds will be biocompatible, able to bear loads, and will be gradually replaced by natural bone. The outcomes are expected to benefit the ageing population and people with bone abnormalities.Read moreRead less
Microstructure effect on energy harvesting ability of electrospun fibres. This project aims to provide new knowledge about how to manipulate the energy harvesting ability of electrospun fibrous mats by changing the fibre structure, components and mat configuration. Expected outcomes of the project are new fibrous materials capable of efficiently converting small mechanical forces and sounds into electricity. These high performance energy harvesting fibres will be useful for developing new power ....Microstructure effect on energy harvesting ability of electrospun fibres. This project aims to provide new knowledge about how to manipulate the energy harvesting ability of electrospun fibrous mats by changing the fibre structure, components and mat configuration. Expected outcomes of the project are new fibrous materials capable of efficiently converting small mechanical forces and sounds into electricity. These high performance energy harvesting fibres will be useful for developing new power supplies, self-powered electronics, self-sustainable sensor networks and electronic textiles.Read moreRead less