Jet breakup of emulsions for the production of designer microparticulate drug delivery systems. Drug delivery systems are an important and growing part of the pharmaceutical and biotechnology market. The growth is estimated to be at 23% p.a. and is tied to the requirements for more precise and complex delivery profiles by highly potent drugs or vaccines (bioactives). To achieve the required level of control and precision, improved encapsulation technologies are needed to produce particles of a p ....Jet breakup of emulsions for the production of designer microparticulate drug delivery systems. Drug delivery systems are an important and growing part of the pharmaceutical and biotechnology market. The growth is estimated to be at 23% p.a. and is tied to the requirements for more precise and complex delivery profiles by highly potent drugs or vaccines (bioactives). To achieve the required level of control and precision, improved encapsulation technologies are needed to produce particles of a precise size and narrow size distribution. This project aims to develop an innovative technology for the production of superior uniformly sized particulate drug delivery systems for the delivery of the "next generation" bioactives.Read moreRead less
Ozone-Enhanced Particle Removal in Water Treatment. Combined ozonation/biologically active carbon filtration provides effective contaminant removal while minimizing disinfection by-product formation. However, the cost of installation in conventional water treatment plants is very high. This project will investigate the beneficial influence of ozonation on the micro-flocculation of small particles, with the aim to optimising particle removal by sedimentation prior to filtration. To do this, requi ....Ozone-Enhanced Particle Removal in Water Treatment. Combined ozonation/biologically active carbon filtration provides effective contaminant removal while minimizing disinfection by-product formation. However, the cost of installation in conventional water treatment plants is very high. This project will investigate the beneficial influence of ozonation on the micro-flocculation of small particles, with the aim to optimising particle removal by sedimentation prior to filtration. To do this, requires a clear understanding of how dissolved ozone interacts with particle surfaces for different water chemistries. The ideal outcome would be to develop a robust water treatment system that required BAC filtration only and eliminated the need for a conventional sand filtration stage as well.Read moreRead less
Scalable, high throughput microfluidic platforms for tissue specific biomaterials development and tissue genesis. The co-development of novel biomaterial platforms and new generation production methods for tissue analogues will provide the necessary stimulus for improved and more relevant methods of enhanced repair or regeneration of diseased or damaged tissues. These outcomes will result in faster time-to-market new generation therapeutic products for Australia and the world. These advances wil ....Scalable, high throughput microfluidic platforms for tissue specific biomaterials development and tissue genesis. The co-development of novel biomaterial platforms and new generation production methods for tissue analogues will provide the necessary stimulus for improved and more relevant methods of enhanced repair or regeneration of diseased or damaged tissues. These outcomes will result in faster time-to-market new generation therapeutic products for Australia and the world. These advances will have a significant impact on our healthcare costs and the quality of life for all Australians.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100155
Funder
Australian Research Council
Funding Amount
$495,000.00
Summary
High-Speed Particle Image Velocimetry and Laser-Induced Fluorescence Facility. This state-of-the-art laser facility will increase our scientific understanding of industrial processes by providing valuable information on velocity, temperature and concentration profiles for rapidly changing flow fields. Previously it was not possible to do this, and the knowledge gained will be applied to develop more efficient and environmentally sustainable operations. For example, many current processes have hi ....High-Speed Particle Image Velocimetry and Laser-Induced Fluorescence Facility. This state-of-the-art laser facility will increase our scientific understanding of industrial processes by providing valuable information on velocity, temperature and concentration profiles for rapidly changing flow fields. Previously it was not possible to do this, and the knowledge gained will be applied to develop more efficient and environmentally sustainable operations. For example, many current processes have high energy input but scientific evidence suggests that it can be reduced if the embodied energy of the flow is properly utilised. Importantly, this utilisation often leads to increased yields and product quality. The facility will greatly assist researchers and industry collaborators in developing processes for the 21st century.Read moreRead less