Low Strength Silver Fluoride Solutions As Clinically Effective Bacteriostatic And Cariostatic Agents
Funder
National Health and Medical Research Council
Funding Amount
$147,800.00
Summary
Scientific evidence indicates that low concentrations of silver are effective in countering bacteria involved in dental decay, and that solutions of silver fluoride are effective in stopping progression of dental decay. This study aims to determine the effectiveness of low strength silver fluoride solutions in the clinical management of dental decay in children. Such solutions may provide a simplified technique for controlling dental decay in populations which lack traditional resources
Fluoridation Of Water Supplies In Remote Indigenous Communities In The NT: Requirements, Feasibility & Cost Effectivenes
Funder
National Health and Medical Research Council
Funding Amount
$72,559.00
Summary
The project has two major objectives: 1) to identify Indigenous communities that are likely to benefit most from fluoridation of the water supply, and 2) to examine the feasibility and impact of introducing a small scale fluoridation plant into at least one community. The first will be achieved through accurately mapping natural levels of fluoride in the water supply of Indigenous communities across the Northern Territory, and examining the oral health status of children in these communities. Th ....The project has two major objectives: 1) to identify Indigenous communities that are likely to benefit most from fluoridation of the water supply, and 2) to examine the feasibility and impact of introducing a small scale fluoridation plant into at least one community. The first will be achieved through accurately mapping natural levels of fluoride in the water supply of Indigenous communities across the Northern Territory, and examining the oral health status of children in these communities. The second will be achieved by installing a fluoridation plant in one or more communities that have been lobbying for fluoridation of their water supplies, and monitoring the maintenance requirements and costs of the plant, and the changes in dental health status in school children over a period of two to three years.Read moreRead less
Randomised Control Trial Of Effectiveness Of Silver Fluoride In Managing Deciduous Dental Caries In Remote Aboriginal Communities
Funder
National Health and Medical Research Council
Funding Amount
$695,220.00
Summary
This study seeks to test a non-invasive treatment for dental decay in young children which may prevent the progression of the decay further into the tooth. This treatment is currently used in some areas. Dental decay is very common in young children in remote communities where access to dental care is often limited. The treatment may reduce pain and oral and facial infections sometimes leading to hospitalisation.
Dental caries (tooth decay) is initiated by demineralisation of tooth hard tissue by organic acids produced by dental plaque bacteria from dietary sugars. The disease is a major public health problem and has an estimated economic burden in Australia of over $1 billion p.a. being higher than that for any other dietary-related disease. We have discovered and patented a novel amorphous calcium fluoride phosphate that is stabilised by phosphopeptides from the bovine milk protein casein. These comple ....Dental caries (tooth decay) is initiated by demineralisation of tooth hard tissue by organic acids produced by dental plaque bacteria from dietary sugars. The disease is a major public health problem and has an estimated economic burden in Australia of over $1 billion p.a. being higher than that for any other dietary-related disease. We have discovered and patented a novel amorphous calcium fluoride phosphate that is stabilised by phosphopeptides from the bovine milk protein casein. These complexes, designated CPP-ACFP, have the potential to provide superior clinical efficacy in preventing dental caries and treating and repairing early stages of disease. The aims of this project therefore are (i) to develop topical formulations of CPP-ACFP for application to teeth to repair early stages of decay and (ii) to characterise the three-dimensional structure of the CPP-ACFP complexes. The significance of this work is that a superior and novel treatment for dental caries may be developed as well as providing insight into the structure of organically-stabilised amorphous calcium phosphate and its role in biomineralisation processes.Read moreRead less
The Common Risk Factor Approach To Assess Relationships Between Dental Caries And Adiposity In Disadvantaged Preschool Children
Funder
National Health and Medical Research Council
Funding Amount
$346,449.00
Summary
Dental decay and obesity in early childhood continues to be a significant health concern in Australian children. Current evidence suggests that these diseases are highly prevalent among children living in disadvantaged areas but the evidence of the relationship is limited. This increases their risk to carry the burden in adulthood. The present proposal uses a "common risk factor approach" to explore relationships between dental decay and obesity in disadvantaged preschool children in Australia.
Natural History And Longterm Impact Of Dental Fluorosis
Funder
National Health and Medical Research Council
Funding Amount
$345,184.00
Summary
Dental fluorosis is an important aspect of oral health because: perception and concerns about fluorosis influence perspective and success of fluoride programs; and advices on fluoride use are based on a risk-benefit tradeoff. This study is expected to report changes in fluorosis, its longterm impact and evaluate fluorosis and caries trade-off. This will be the first study of the natural history of fluorosis. Findings will have significance for individuals, dental profession and health policy.