Removing the impediment to large-scale selective breeding of Australian barramundi: deciphering and manipulating the genetic basis of sex change. This project will determine the genetic basis of sex control in barramundi and develop technologies to allow barramundi hatcheries to have increased control over reproduction leading to more efficient propagation and removing impediments to selective breeding.
Striking Gold - Determining the genetics of gold skin colour in barramundi. Barramundi is one of Australia’s finest eating table fish and the species is gaining global prominence. However, fillet flesh colour of Australian farmed barramundi exhibit greyish tones which lowers consumer acceptance compared to other white flesh fish and imported product. Barramundi with rare golden skin tones do not exhibit this flesh "greyness" and are therefore a valuable niche product to farm if they can be produ ....Striking Gold - Determining the genetics of gold skin colour in barramundi. Barramundi is one of Australia’s finest eating table fish and the species is gaining global prominence. However, fillet flesh colour of Australian farmed barramundi exhibit greyish tones which lowers consumer acceptance compared to other white flesh fish and imported product. Barramundi with rare golden skin tones do not exhibit this flesh "greyness" and are therefore a valuable niche product to farm if they can be produced in larger numbers. This project will elucidate the genetic basis and mechanism of expression behind the golden barramundi phenotype. In doing so, it will enable barramundi farmers to produce them at commercially relevant scales, providing them with a substantial competitive advantage in both domestic and global markets.Read moreRead less
Industrial Transformation Research Hubs - Grant ID: IH210100014
Funder
Australian Research Council
Funding Amount
$4,996,503.00
Summary
ARC Research Hub for Supercharging Tropical Aquaculture Through Genetic Solutions. This project will deliver the genetic knowledge to instigate world-leading and highly productive breeding programs for five tropical aquaculture species (barramundi, pearl oyster, prawn, grouper and marine algae) in northern Australia. It will integrate cutting edge genetic and genomic approaches into innovative aquaculture enterprises and will establish a novel understanding of the genetic basis of disease resist ....ARC Research Hub for Supercharging Tropical Aquaculture Through Genetic Solutions. This project will deliver the genetic knowledge to instigate world-leading and highly productive breeding programs for five tropical aquaculture species (barramundi, pearl oyster, prawn, grouper and marine algae) in northern Australia. It will integrate cutting edge genetic and genomic approaches into innovative aquaculture enterprises and will establish a novel understanding of the genetic basis of disease resistance and how the production environment interfaces with the bacterial microbiome, pathogens and water quality to cause disease. Outcomes will lead to increased productivity, international competitiveness, and lowered disease risk and significantly expand Australia's capacity in the aquaculture sector.Read moreRead less
Understanding fish-killing mechanisms by harmful algal blooms: towards the design of effective mitigation strategies. Fish-killing microalgal blooms cause multi-million dollar losses to global aquaculture and wild fisheries. This project brings together leading Australian and Canadian research teams, applying sophisticated cell line and biologically active molecule technologies, to elucidate precise fish-kill mechanisms and design effective mitigation strategies.
Fighting disease on farms: how do vaccinations drive evolution of new pathogen strains? Vaccinating against some types of infectious diseases can drive evolution of new variants of the pathogen. This project will show how bacterial populations evolve in response to vaccination in farms, leading to new vaccination strategies and improved vaccine formulations to better control diseases that are caused by highly variable bacteria.
A pan-genome reverse vaccinology approach to disease prevention in farmed fish. Evolution of new pathogen strains causes major problems in vaccinated animals because these variants can reinfect and cause severe disease in previously protected animals. This project will use state-of-the-art genomics to find new targets that are essential to all strain variants, enabling development of broadly cross-protective vaccines for farmed animals.
Early Career Industry Fellowships - Grant ID: IE230100648
Funder
Australian Research Council
Funding Amount
$472,027.00
Summary
Novel reproductive approaches to de-risk and transform barramundi breeding. Demand for Australian seafood outstrips supply. Farming of the iconic Australian barramundi is poised to play a major role addressing this shortfall; but innovative methods are needed to de-risk breeding processes and to provide precise control of maturation, spawning and genetic contribution of broodstock. This project, in partnership with the world’s largest barramundi breeding company, will develop, test and apply nov ....Novel reproductive approaches to de-risk and transform barramundi breeding. Demand for Australian seafood outstrips supply. Farming of the iconic Australian barramundi is poised to play a major role addressing this shortfall; but innovative methods are needed to de-risk breeding processes and to provide precise control of maturation, spawning and genetic contribution of broodstock. This project, in partnership with the world’s largest barramundi breeding company, will develop, test and apply novel breeding methods to obtain tight control over barramundi reproductive development and spawning. By combining cutting-edge genetic and applied breeding techniques, selective breeding programs will be more efficient and the genetic gains from breeding programs will be maximised.Read moreRead less
Characterisation of vital carbohydrate synthases in pathogenic oomycetes. This project aims to understand the mechanisms that control cell wall stability in the fish pathogen, Saprolegnia parasitica. The biochemical properties and function of vital enzymes involved in cell wall biosynthesis will be determined using innovative approaches at the interface of biochemistry, microbiology, cell biology, and structural biology. Next generation ion mobility mass spectrometry will be used to solve challe ....Characterisation of vital carbohydrate synthases in pathogenic oomycetes. This project aims to understand the mechanisms that control cell wall stability in the fish pathogen, Saprolegnia parasitica. The biochemical properties and function of vital enzymes involved in cell wall biosynthesis will be determined using innovative approaches at the interface of biochemistry, microbiology, cell biology, and structural biology. Next generation ion mobility mass spectrometry will be used to solve challenging structural questions that cannot be tackled with conventional techniques. Expected outcomes include new knowledge on challenging membrane proteins that allows development of novel strategies for disease control in aquaculture. The data may also be applicable to crop protection from related plant pathogens.Read moreRead less