Diet And The Gut Microbiota As The Basis For Food Allergies
Funder
National Health and Medical Research Council
Funding Amount
$669,091.00
Summary
Diet and the composition of the gut microbiota represent new avenues to prevent or treat human diseases. We propose that allergies in western countries result from altered gut homeostasis. This application seeks to understand all the molecules involved, and to discover new bacteria that associate with, or protect from allergies.
Dietary Modulation Of Maternal Gut Flora With Oligosaccharides In Pregnancy As A Novel Allergy Prevention Strategy
Funder
National Health and Medical Research Council
Funding Amount
$1,681,512.00
Summary
Declining intake of dietary fibre is a major factor implicated in the changing profile of healthy gut bacteria, and the associated increase in many inflammatory diseases including childhood allergy. This clinical trial aims to confirm findings in animal studies that increased dietary fibre in pregnancy can prevent allergy in the offspring, by favourably influencing metabolism and immune function during pregnancy.