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Cardiac Function In The Growth Restricted Fetus: The Effects Of Betamethasone And Melatonin
Funder
National Health and Medical Research Council
Funding Amount
$402,872.00
Summary
I am an Obstetrician interested in the problems of growth-restricted babies. Devastatingly, many of these babies do not survive pregnancy and survivors face difficult challenges throughout their lifetime. My research uses the latest ultrasound technology to study their heart while still in the womb, evaluating if our current treatments are safe or possibly harmful, and finally testing melatonin as an antioxidant to protect their heart from damage they may sustain while still in the womb.
Each year approximately 24,000 Australian children are born too early. A new international study led by Western Australian researchers is studying the role that genetics play in preterm birth. This study will evaluate the genomes of 10,000 women of which 2,000 come from Western Australia. It is anticipated that this study will advance our knowledge about the genetic basis of preterm birth and assist in providing customised clinical care to those at highest risk.
Defining Epigenetic Predictors Of Long-term Outcomes Of Preterm Birth
Funder
National Health and Medical Research Council
Funding Amount
$409,408.00
Summary
On average, those born premature do worse health-wise than those born at term. However, some do worse than others. Our aim is to identify these people at birth to better help doctors and parents to closely monitor their health. For this, we will be “reading the diary of pregnancy” in the molecules added to chromosomes in blood during pregnancy in young adults with will characterised states of health. We will analyse DNA from blood that we will extract from stored heel prick spots.
Implications Of Early Life And Contemporary Influences On Body Composition, Mental Health, And Precursors Of Chronic Diseases In The Aboriginal Birth Cohort Study
Funder
National Health and Medical Research Council
Funding Amount
$2,335,405.00
Summary
Aboriginal babies across the Top End of the Northern Territory have been followed up for over 25 years as part of the Aboriginal Birth Cohort Study. The aim of this study is to relate early life events, beginning in the womb, to later physical and mental health. This will identify early those most at risk of developing chronic diseases (diabetes, cardiovascular, renal and mental health) that contribute to the current gap in life expectancy between Aboriginal and non- Aboriginal Australians, and ....Aboriginal babies across the Top End of the Northern Territory have been followed up for over 25 years as part of the Aboriginal Birth Cohort Study. The aim of this study is to relate early life events, beginning in the womb, to later physical and mental health. This will identify early those most at risk of developing chronic diseases (diabetes, cardiovascular, renal and mental health) that contribute to the current gap in life expectancy between Aboriginal and non- Aboriginal Australians, and help develop intervention strategies.Read moreRead less