Early Diagnosis And Management Of Vestibular Neuritis.
Funder
National Health and Medical Research Council
Funding Amount
$174,107.00
Summary
Acute Vestibular Neuritis is a common and self-limiting cause of disabling vertigo lasting >24 hours. Posterior Circulation Stroke is a less common but life-threatening disorder that presents with the same symptoms. These two disorders are separable by three key examination findings: the Head Impulse, Nystagmus, Tests of Skew ("HINTS). This fellowship will implement effective separation of the common harmless cause of vertigo from life-threatening strokes and ensure early treatment of Neuriti ....Acute Vestibular Neuritis is a common and self-limiting cause of disabling vertigo lasting >24 hours. Posterior Circulation Stroke is a less common but life-threatening disorder that presents with the same symptoms. These two disorders are separable by three key examination findings: the Head Impulse, Nystagmus, Tests of Skew ("HINTS). This fellowship will implement effective separation of the common harmless cause of vertigo from life-threatening strokes and ensure early treatment of Neuritis with steroids and home rehabilitation.Read moreRead less
Strabismus is the pathological misalignment of the eyes associated with loss of binocular vision and is one of the most common human ophthalmological disorders. Patients with comitant strabismus have full eye movements, whereas patients with incomitant strabismus have limited eye movements, which causes the angle of strabismus to vary with gaze direction. This project aims to define genetic contributors to comitant congenital strabismus.
Eye Movements And The Neural Representation Of Visual Space
Funder
National Health and Medical Research Council
Funding Amount
$459,061.00
Summary
This project will investigate the brain mechanisms that underlie our ability to perceive the locations of objects using vision. This fundamental ability supports a range of important functions including visually-guided reaching, navigation during walking, and spatial awareness, but remains poorly understood. Using physiological, behavioural, and analytical methods, this project will fill a key knowledge gap in visual neuroscience and form a basis for a range of clinical and biomedical advances.
The Neuro-ophthalmological Manifestations Of Human Mitochondrial Diseases.
Funder
National Health and Medical Research Council
Funding Amount
$100,675.00
Summary
Human mitochondrial diseases often result in neuro-ophthalmological abnormalities. We aim to examine a cohort of patients with mitochondrial disease and document the type and degree of neuro-ophthalmological abnormality. We will provide detail on the retina, optic nerve, oculomotor function, eyelids and visual acuity. We will examine the optic nerve in detail and perform optical coherence tomography and visual evoked potentials on each patient. We will compare results to age-matched controls.
Ictal Characteristics Of Common Vestibular Diseases
Funder
National Health and Medical Research Council
Funding Amount
$281,573.00
Summary
vertigo is a disabling symptom affecting 1 million Australians at any given time. Acute vertigo is associated with abnormal eye movements or nystagmus, the pattern of which points to its origin. In this project, we extract the unique characteristics of distinct vertigo syndromes to enable their separation
Spatial Coding In The Primate Cortex During Eye Movements.
Funder
National Health and Medical Research Council
Funding Amount
$428,720.00
Summary
Every time we move our eyes, objects in the world change their positions on the retina, yet to us, their positions remain perceptually unchanged. This project seeks to understand how neurons in the primate brain combine visual input with signals about eye position to construct this stable representation of external space. The findings will help us understand and-or rehabilitate a host of nervous system dysfunctions, including schizophrenia, stroke, and paraplegia.
More than half of the people living with Alzheimer’s disease experience visual impairments. These impairments may appear before memory problems begin to surface. This research investigates how those at risk of dementia explore the world visually, and how this changes over time. The findings will inform the design of dementia-friendly environments and answer the question whether the assessment of eye movement adds to the diagnosis and prognosis of cognitive impairments.
Novel Approaches To Understanding Peripheral Vision In Patients With Central Vision Loss
Funder
National Health and Medical Research Council
Funding Amount
$367,101.00
Summary
The aim of my research is to develop novel interventions that enhance the peripheral vision of patients with central vision loss, and to investigate the neural correlates of visual perception in peripheral vision in typical adults. My research will inform rehabilitation strategies that optimise the visual function of patients with partial blindness, and provide a more thorough understanding of the underlying neural mechanisms that reduce the quality of peripheral vision.
The Effect Of Visual Impairment Arising From The Eye Diseases Glaucoma And Age-related Maculopathy On Driving Safety
Funder
National Health and Medical Research Council
Funding Amount
$645,591.00
Summary
Driving-related injuries are a serious public health problem for older people. Visual impairment is a significant risk factor for crashes. This prospective study will determine how the eye diseases glaucoma and age-related macular degeneration impact on driving safety. The outcomes will be used to develop a simple, reliable and practical battery of tests that can identify those at risk of crashes and to inform screening and intervention programs, patient education and driver licensing.