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2026 ARDC Annual Survey is now open!

The Australian Research Data Commons (ARDC) invites you to participate in a short survey about your interaction with the ARDC and use of our national research infrastructure and services. The survey will take approximately 5 minutes and is anonymous. It’s open to anyone who uses our digital research infrastructure services including Reasearch Link Australia.

We will use the information you provide to improve the national research infrastructure and services we deliver and to report on user satisfaction to the Australian Government’s National Collaborative Research Infrastructure Strategy (NCRIS) program.

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Australian State/Territory : QLD
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Research Topic : Expert Systems
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    Investigating Post-transcriptional Gene Regulation In Cancer

    Funder
    National Health and Medical Research Council
    Funding Amount
    $645,205.00
    Summary
    In this program, I will enhance our understanding of cancer gene regulation and provide novel avenues for the treatment of aggressive tumours. Using own data and that from collaborators, I will determine patterns of gene regulation in blood cancers and identify markers that predict disease outcome. I aim to understand how gene regulation can transform healthy cells into tumour cells and whether personalised treatment can kill tumour cells more effectively and prevent relapse and metastasis.
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    Funded Activity

    Development And Application Of A Mendelian Randomization Framework Aimed At Dissecting The Biological Basis Of Ankylosing Spondylitis And Other Complex Diseases

    Funder
    National Health and Medical Research Council
    Funding Amount
    $279,666.00
    Summary
    Our aim is to identify genes and biological molecules that cause a type of autoimmune arthritis called ankylosing spondylitis. Our approach involves finding combinations of genes that are related to biological molecules of interest and then testing to see whether the gene combination is also related to risk of disease. We hope that our strategy will lead to new drug treatments targeting the condition.
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    Funded Activity

    Quality Improvement In Indigenous Primary Health Care: Leveraging Effective Ambulatory Practices (LEAP)

    Funder
    National Health and Medical Research Council
    Funding Amount
    $1,144,570.00
    Summary
    Although much is known about best practice in quality improvement in Indigenous Primary Health Care Services, getting this into practice remains challenging. The LEAP project works in partnership with health services to i) identify challenges faced when improving care; ii) design and trial interventions to address these challenges; and iii) evaluate how this process works in different settings.
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    Funded Activity

    Modulating Skin Regenerative Responses To Improve Wound Repair And Fight Carcinogenesis

    Funder
    National Health and Medical Research Council
    Funding Amount
    $470,144.00
    Summary
    Skin disorders, such as hard to heal wounds or the most common skin cancers, are a major burden on the national health system. Despite their different nature they employ similar mechanisms of response to injury. In this project we intend to develop a comprehensive understanding of the genetic and molecular mechanisms at play to allow clinical interventions to prevent or to cure these disorders.
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    Funded Activity

    Immuno-polymeric Drugs For Prostate Cancer Therapy

    Funder
    National Health and Medical Research Council
    Funding Amount
    $626,995.00
    Summary
    Prostate cancer is the most common cancer in men over 50 and the second most frequent cause of cancer deaths in Western society. Docetaxel is the first line of chemotherapy when other intervention strategies are unsuccessful, but 30% of patients suffer from severe side-effects. To address this problem, we will utilise carriers for docetaxel that directly target prostate tumours using a novel antibody approach. This increases accumulation at the tumour site while decreasing off-target toxicity.
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    Funded Activity

    An Innovation Platform For Systems-Wide Improvement In Indigenous Primary Health Care

    Funder
    National Health and Medical Research Council
    Funding Amount
    $2,592,418.00
    Summary
    The CRE for Integrated Quality Improvement (CRE-IQI) will improve Aboriginal and Torres Strait Islander health outcomes by accelerating and strengthening large-scale primary health care (PHC) quality improvement efforts. As an Innovation Platform, it will build on and extend the work of the ABCD National Research Partnership, and leverage the efforts of researchers, service providers and policy makers to address priority areas for development of IQI in Aboriginal and Torres Strait Islander PHC.
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    Funded Activity

    Systems Analysis Of Epidermal Biology And Cancer

    Funder
    National Health and Medical Research Council
    Funding Amount
    $1,301,256.00
    Summary
    Squamous cell carcinoma of the skin is extremely common in Australia, resulting in disfiguring surgeries and deaths. Although cumulative sun exposure is important, some people are very susceptible, and we do not know why. This project hinges on the notion that skin cancer is a complex (many genes involved). We will utilize novel systems to harness this complexity to understand why some people are resistant and others very susceptible so as to design appropriate control measures and treatments.
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    Showing 1-7 of 7 Funded Activites

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