Development Of A Novel Bioengineered Tissue Construct For Repairing The Eye.
Funder
National Health and Medical Research Council
Funding Amount
$335,817.00
Summary
Corneal diseases are often treated using donor tissue transplants. Nevertheless, donor tissue is unsuitable for treating the peripheral or limbal margin of the cornea. We have therefore developed a way to transplant sheets of limbal tissue (epithelium) grown in the laboratory from a patient's own cells, but this tissue lacks a foundation of connective tissue that we believe is essential for sustained healing. Thus, our aim is to develop a novel limbal transplant which contains both layers.
Translating Genetic Determinants Of Glaucoma Into Better Diagnosis And Treatment
Funder
National Health and Medical Research Council
Funding Amount
$9,466,000.00
Summary
Glaucoma is the leading cause of irreversible blindness worldwide. By 2020, it will affect 80 million people, and in Australia over the next decade, the overall cost of glaucoma will reach $4.3 billion per annum. This Program will use genetic advances to personalise treatment. Blindness will be prevented in individuals at highest risk, new ways to treat patients will be developed, and better outcomes for patients will result from less treatment and monitoring of low risk cases.
Most eye diseases have a genetic contribution, whether rare disorders affecting children such as retinoblastoma or congenital cataracts through to common disorders of older people such as myopia, age-related macular degeneration or glaucoma. We will continue our successful research to find genes that cause these diseases and use this to improve patient care and prevent blindness. We will work out how families can use this genetic information to participate in trials to develop new treatments.
Young Adult Myopia: Genetic And Environmental Associations
Funder
National Health and Medical Research Council
Funding Amount
$809,271.00
Summary
Myopia affects 80% of school leavers in the cities of East Asia, 45% of Asian Australian school leavers and is probably on the rise in European Australian adolescents. Increased levels of education and lack of time outdoors are known to increase the risk of myopia. We will examine 2,000 young adults to find the genes that interact with these risk factors. In addition to confirming when these risk factors are most important, identifying molecular pathways opens the avenue of new treatments.
Using behavioural economic insights to overcome student procrastination. This project aims to study the relations between present-biased time preference, procrastination, and achievement at school, using economic experiments. Investment in human capital generates economic benefits for students, families, employers, and society, but its benefits are realised far into the future. Because of these immediate costs and delayed benefits, behavioural economic theory predicts that students will procrast ....Using behavioural economic insights to overcome student procrastination. This project aims to study the relations between present-biased time preference, procrastination, and achievement at school, using economic experiments. Investment in human capital generates economic benefits for students, families, employers, and society, but its benefits are realised far into the future. Because of these immediate costs and delayed benefits, behavioural economic theory predicts that students will procrastinate. This project will identify the characteristics of students at greatest risk of procrastination, evaluate practical strategies to overcome it, and examine whether it is associated with poorer outcomes. This should help schools and policy makers reduce educational inequalities, and yield long-term benefits over students’ lives.Read moreRead less
Strabismus is the pathological misalignment of the eyes associated with loss of binocular vision and is one of the most common human ophthalmological disorders. Patients with comitant strabismus have full eye movements, whereas patients with incomitant strabismus have limited eye movements, which causes the angle of strabismus to vary with gaze direction. This project aims to define genetic contributors to comitant congenital strabismus.
Discovery Early Career Researcher Award - Grant ID: DE120101270
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
The behavioural birthdate effect: the impact of relative position within cohorts on risk aversion, self-confidence and aspiration levels. The 'birthdate effect' describes the phenomenon where children born just after the school entry cut off date are more successful in life than those born just before. This project will study why these children make very different life choices, those born just after the cut-off date are expected to take greater risks and have higher self esteem.
Incentivizing Attendance and Performance at School: A Field Experiment. This project aims to develop and evaluate an incentive-based program to increase the school attendance and performance of Indigenous students to help alleviate current inequalities between Indigenous and non-indigenous Australians. Only 43 per cent of Indigenous Australians graduate from high school compared to 78 per cent for non-Indigenous Australians. The study plans to investigate whether high value rewards (e.g. driving ....Incentivizing Attendance and Performance at School: A Field Experiment. This project aims to develop and evaluate an incentive-based program to increase the school attendance and performance of Indigenous students to help alleviate current inequalities between Indigenous and non-indigenous Australians. Only 43 per cent of Indigenous Australians graduate from high school compared to 78 per cent for non-Indigenous Australians. The study plans to investigate whether high value rewards (e.g. driving licence instruction) are effective in incentivising year 11 and 12 students. It also aims to examine whether the way incentives are provided — ex-post as traditionally done or ex-ante in the form of a trust-based contract — increase high school completion rates of Indigenous students where previous incentive schemes have failed.Read moreRead less
The economics of (mis)information in the age of social media. New media technologies allow anyone to broadcast their views, leading to a “cacophony of voices” where misinformation flourishes. Tools from information economics are tailor-made for understanding information consumption in settings with many biased news sources. We develop economic models where many sources compete to attract and influence heterogenous listeners. We then study how misinformation spreads and amplifies when consumers ....The economics of (mis)information in the age of social media. New media technologies allow anyone to broadcast their views, leading to a “cacophony of voices” where misinformation flourishes. Tools from information economics are tailor-made for understanding information consumption in settings with many biased news sources. We develop economic models where many sources compete to attract and influence heterogenous listeners. We then study how misinformation spreads and amplifies when consumers of information communicate with many others through a social network. Finally, we study how to design simple and robust rules to foster informative discourse and filter misinformation. The results will shape economic policy recommendations for regulating misinformation in media platforms and social media.Read moreRead less