Engineering floating liquid marbles for three-dimensional cell cultures. This project aims to understand the physics of three-dimensional cell cultures in a liquid marble floating on a liquid free surface. New methodology developed can produce these cell cultures without using matrices or scaffolds and with run-times well beyond existing technologies. This methodology closely mimics a normal in-vivo environment and produces spheroids needed in cell transplantation therapies. This project will re ....Engineering floating liquid marbles for three-dimensional cell cultures. This project aims to understand the physics of three-dimensional cell cultures in a liquid marble floating on a liquid free surface. New methodology developed can produce these cell cultures without using matrices or scaffolds and with run-times well beyond existing technologies. This methodology closely mimics a normal in-vivo environment and produces spheroids needed in cell transplantation therapies. This project will resolve uncertainties in the underlying phenomena. The expected outcome should support future high quality cell cultures suitable for transplantation therapies.Read moreRead less
New bar-encoded polymer microbeads for multiplexed bioanalysis-a quick and high-throughput approach for complex disease diagnosis. Distinguishable new bar-encoded (element-encoded) polymer microbeads associated with a mass spectroscopy-flow cytometer detector provide a novel platform for highly multiplexed biological analysis. Such an approach can simultaneously identify many non-self-agents at low concentrations, which facilitates early-stage complex disease diagnosis.
Conducting polymer materials. This project aims to understand the optical, electrical and optoelectronic properties of conductive polymers by studying how ions influence the charge transport through the polymeric structure. The discovery of conductive polymers in the 1970s led to smartphone and laptop touch displays and solar cells. These materials promise even more still – but how they operate at the atomic level is not understood. This project could lead to an ability to harness and control th ....Conducting polymer materials. This project aims to understand the optical, electrical and optoelectronic properties of conductive polymers by studying how ions influence the charge transport through the polymeric structure. The discovery of conductive polymers in the 1970s led to smartphone and laptop touch displays and solar cells. These materials promise even more still – but how they operate at the atomic level is not understood. This project could lead to an ability to harness and control these properties for energy storage and wearable displays. These materials’ biological neutrality could lead to drug delivery and sensing applications in the agriculture and healthcare spaces.Read moreRead less
A New Generic Approach for Assessing Blast Effects on Reinforced Concrete Members. A framework allow for both flexural and shear response analysis using a new segmental approach is developed in this proposal. A blast test program is designed to validate the framework for reinforced concrete members. The validated framework is then used to derive normalised pressure impulse programs for reinforced members in unconfined and confined spaces. This project will provide design engineers guidelines for ....A New Generic Approach for Assessing Blast Effects on Reinforced Concrete Members. A framework allow for both flexural and shear response analysis using a new segmental approach is developed in this proposal. A blast test program is designed to validate the framework for reinforced concrete members. The validated framework is then used to derive normalised pressure impulse programs for reinforced members in unconfined and confined spaces. This project will provide design engineers guidelines for reliably and quickly assessing the effect of different kinds of blast loads on different types and properties and geometries of reinforced concrete structural members, saving computation time and efforts while providing increased realism and accuracy.Read moreRead less
Engineering improved technology for nanoparticle-based adjuvant manufacture. Over the next decade nanotechnology will redefine vaccines for animal and human health. Nanoparticle adjuvants will boost engineered vaccines that use minimal antigens such as recombinant proteins and synthetic peptides. This project aims to develop a platform technology for making and controlling the properties of inulin nanoparticles by optimising the engineering and manufacturing aspects of inulin nanoparticles to fu ....Engineering improved technology for nanoparticle-based adjuvant manufacture. Over the next decade nanotechnology will redefine vaccines for animal and human health. Nanoparticle adjuvants will boost engineered vaccines that use minimal antigens such as recombinant proteins and synthetic peptides. This project aims to develop a platform technology for making and controlling the properties of inulin nanoparticles by optimising the engineering and manufacturing aspects of inulin nanoparticles to fundamentally understand the relationship between physical-chemical properties and efficacy. Completion of this project aims to produce potent nanoparticle-based adjuvants underpinned by novel manufacturing technology, to ultimately facilitate the development of more effective and protective vaccines for animals and humans.Read moreRead less
Nanostructured Electrocatalysts for Clean Fuels Production. This project aims to develop single-component and hybrid transition-metal and metal-free electrocatalysts with controllable nanostructures to efficiently and selectively catalyse carbon dioxide reduction and hydrogen evolution reactions for clean fuels production including hydrogen and low-carbon organic molecules. By combining experimental and theoretical modelling, this project plans to reveal the origins, mechanism and pathway of the ....Nanostructured Electrocatalysts for Clean Fuels Production. This project aims to develop single-component and hybrid transition-metal and metal-free electrocatalysts with controllable nanostructures to efficiently and selectively catalyse carbon dioxide reduction and hydrogen evolution reactions for clean fuels production including hydrogen and low-carbon organic molecules. By combining experimental and theoretical modelling, this project plans to reveal the origins, mechanism and pathway of these reactions, and the effect of catalyst composition and morphology on their performance. The resulting nanostructured catalysts are of great importance for feasible clean fuel generation and carbon dioxide reduction.Read moreRead less
Combining transient micro-reflections and multi-sensor arrays for condition assessment of buried pipes. This project will develop an accurate and reliable approach for assessing the condition of pipelines. This new approach will reduce costs and save considerable amounts of water each year, as it will assist utilities in preventing major failures such as pipe bursts, and performing strategically targeted maintenance, replacement and rehabilitation.
Cost Effective Pipeline Condition Assessment Using Paired Pressure Sensor Arrays. Water distribution networks represent society's most important infrastructure asset. They are buried pipes and are often old and deteriorating. Cost-effective methods to assess their physical condition are urgently needed. This research will develop a novel and advanced approach to determine the interior condition of pipes quickly and effectively using small water hammer pulses or waves. Paired pressure sensor arra ....Cost Effective Pipeline Condition Assessment Using Paired Pressure Sensor Arrays. Water distribution networks represent society's most important infrastructure asset. They are buried pipes and are often old and deteriorating. Cost-effective methods to assess their physical condition are urgently needed. This research will develop a novel and advanced approach to determine the interior condition of pipes quickly and effectively using small water hammer pulses or waves. Paired pressure sensor arrays will be used to measure reflections of the waves in pipes and these methods will enable finer resolution and identification of pipeline faults, such as wall thickness loss and leakage while at the same time allowing operational continuity. The outcome will be powerful tools to more cost effectively manage these crucial assets.Read moreRead less
High-resolution pipeline condition assessment using hydraulic transients. This project aims to develop urgently needed non-invasive methods to assess fine detail of a pipe’s condition and allow ‘just in time’ predictive repair. Water distribution networks are society's most important infrastructure asset. They consist of buried pipes that are often old and deteriorating, and annual maintenance overhead exceeds $1 billion per year in Australia alone. The project will develop cost-effective powerf ....High-resolution pipeline condition assessment using hydraulic transients. This project aims to develop urgently needed non-invasive methods to assess fine detail of a pipe’s condition and allow ‘just in time’ predictive repair. Water distribution networks are society's most important infrastructure asset. They consist of buried pipes that are often old and deteriorating, and annual maintenance overhead exceeds $1 billion per year in Australia alone. The project will develop cost-effective powerful tools to identify faults, such as pipe wall corrosion and blockages, while allowing operational continuity. The expected outcome is high-resolution images of wall condition of pipes using high-frequency pressure transients and sophisticated fibre optic sensor arrays.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE150100078
Funder
Australian Research Council
Funding Amount
$190,000.00
Summary
An advanced multimodal terahertz spectroscopy and imaging system for WA. An advanced multimodal terahertz spectroscopy and imaging system: Terahertz (THz) technology is in use in diverse applications from semiconductor inspection, metamaterials, biology and protein analysis, pharmaceutical sciences and formulations; security and surveillance, and biomedical imaging for burn assessment and cancer detection. This project will provide researchers with access to state-of-the-art THz spectroscopy and ....An advanced multimodal terahertz spectroscopy and imaging system for WA. An advanced multimodal terahertz spectroscopy and imaging system: Terahertz (THz) technology is in use in diverse applications from semiconductor inspection, metamaterials, biology and protein analysis, pharmaceutical sciences and formulations; security and surveillance, and biomedical imaging for burn assessment and cancer detection. This project will provide researchers with access to state-of-the-art THz spectroscopy and imaging facilities, resulting in high-impact outcomes across the physical and biological sciences and engineering, broadly contributing to Australia's economic and social well being.Read moreRead less