Engineering floating liquid marbles for three-dimensional cell cultures. This project aims to understand the physics of three-dimensional cell cultures in a liquid marble floating on a liquid free surface. New methodology developed can produce these cell cultures without using matrices or scaffolds and with run-times well beyond existing technologies. This methodology closely mimics a normal in-vivo environment and produces spheroids needed in cell transplantation therapies. This project will re ....Engineering floating liquid marbles for three-dimensional cell cultures. This project aims to understand the physics of three-dimensional cell cultures in a liquid marble floating on a liquid free surface. New methodology developed can produce these cell cultures without using matrices or scaffolds and with run-times well beyond existing technologies. This methodology closely mimics a normal in-vivo environment and produces spheroids needed in cell transplantation therapies. This project will resolve uncertainties in the underlying phenomena. The expected outcome should support future high quality cell cultures suitable for transplantation therapies.Read moreRead less
Magnetofluidic sample handling for enhanced point-of-care diagnosis. This project aims to decipher the mechanism behind recent discovery on the enhancement of mixing and separation with magnetism and to apply it to the rapid and early detection of malaria and cancer. This mechanism provides novel and unique fluid handling capabilities, which allow the development of revolutionary point-of-care diagnostic approaches that integrate magnetic mixing, separation and detection on a single device. The ....Magnetofluidic sample handling for enhanced point-of-care diagnosis. This project aims to decipher the mechanism behind recent discovery on the enhancement of mixing and separation with magnetism and to apply it to the rapid and early detection of malaria and cancer. This mechanism provides novel and unique fluid handling capabilities, which allow the development of revolutionary point-of-care diagnostic approaches that integrate magnetic mixing, separation and detection on a single device. The outcomes of this project are instrumental for the reduction of healthcare cost, promoting good health for Australian and potentially creating new jobs in the niche biomedical industry.Read moreRead less
Dislocation motion and anelastic recovery in layered ceramic titanate. This project aims to research deformation and facture in brittle ceramic nanowire materials and anelastic behaviour in tensile deformation. Layered sodium titanate is used in energy storage and water treatment, but in-situ tensile tests have observed unconventional deformation behaviour, with significant dislocation motion and anelastic recovery. This project will study the deformation mechanism in layered sodium titanate nan ....Dislocation motion and anelastic recovery in layered ceramic titanate. This project aims to research deformation and facture in brittle ceramic nanowire materials and anelastic behaviour in tensile deformation. Layered sodium titanate is used in energy storage and water treatment, but in-situ tensile tests have observed unconventional deformation behaviour, with significant dislocation motion and anelastic recovery. This project will study the deformation mechanism in layered sodium titanate nanowires through molecular dynamics simulations, empirical interatomic potential, and in situ TEM experiments. Expected outcomes include knowledge of the deformation mechanism of this layered titanate which can be broadened to technologically important layered ceramic materials.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE170100241
Funder
Australian Research Council
Funding Amount
$372,000.00
Summary
Seeing deeply inside the body with the world's smallest microscope. This project aims to develop the world's smallest in vivo microscope that can image the interior of living organisms at a subcellular resolution in a minimally invasive way. The project will shrink an entire microscope to the size of an optical fibre – as thin as a single strand of hair – and image deep regions of the central nervous system. This is expected to improve diagnostic tools and the knowledge of degenerative brain dis ....Seeing deeply inside the body with the world's smallest microscope. This project aims to develop the world's smallest in vivo microscope that can image the interior of living organisms at a subcellular resolution in a minimally invasive way. The project will shrink an entire microscope to the size of an optical fibre – as thin as a single strand of hair – and image deep regions of the central nervous system. This is expected to improve diagnostic tools and the knowledge of degenerative brain diseases, including Alzheimer's disease and amyotrophic lateral sclerosis. This project aims to completely transform the landscape of biomedical research and industry, with expected discoveries revolutionising the diagnosis and treatment of brain conditions.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE210101073
Funder
Australian Research Council
Funding Amount
$355,000.00
Summary
Defying conventions with a liquid metal-embedded hybrid elastomer composite. Conductive elastic composites are one of the key components used in flexible/wearable electronic devices in the manufacture of sensors and interconnects; however, conventional composites experience a relatively low sensitivity to strain, and their conductivity decreases when stretched (i.e. they exhibit a negative piezoconductive effect). This project aims to understand the unprecedented positive piezoconductive effect ....Defying conventions with a liquid metal-embedded hybrid elastomer composite. Conductive elastic composites are one of the key components used in flexible/wearable electronic devices in the manufacture of sensors and interconnects; however, conventional composites experience a relatively low sensitivity to strain, and their conductivity decreases when stretched (i.e. they exhibit a negative piezoconductive effect). This project aims to understand the unprecedented positive piezoconductive effect exhibited on the liquid metal-embedded hybrid elastomer (LMHE) and explore its potential to address the key challenges faced by conventional materials. The outcomes of this project will benefit the advanced manufacturing sector by developing high-performance composites to revolutionise future wearable electronic technologies.Read moreRead less
Finite Strain with large rotations: A new hybrid numerical/experimental approach. Deformation up to large strains and rotations is important in rocks, metals, polymers, and biomaterials. Computational mechanics is a standard tool for modelling such deformations. However, in earth sciences, mechanical theories use small-strain formulations or large-strain approaches with classical stress rates. Classical stress rates can lead to incorrect stored energies. This project proposes to test a new large ....Finite Strain with large rotations: A new hybrid numerical/experimental approach. Deformation up to large strains and rotations is important in rocks, metals, polymers, and biomaterials. Computational mechanics is a standard tool for modelling such deformations. However, in earth sciences, mechanical theories use small-strain formulations or large-strain approaches with classical stress rates. Classical stress rates can lead to incorrect stored energies. This project proposes to test a new large-strain theory tailored to rocks experimentally, and to apply it to a pivotal geological problem: shear zone formation. The project will advance our fundamental understanding of the mechanics and energetics of rock deformation and provide a novel tool for the modelling of large deformations.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE210100156
Funder
Australian Research Council
Funding Amount
$289,500.00
Summary
3D Two-Photon Nanoprinter for Advanced Multi-Functional Materials & Devices. The Nanoscribe Photonic Professional GT2 Two-Photon 3D Printer enables tailoring materials’ architecture at nanoscale. This results in unique optical, mechanical, electrical, chemical, biochemical, and acoustic properties enabling a wealth of cutting-edge research activities in variety of fields including mechanical/optical/electrical metamaterials, bioinspired hard/soft materials, biomaterials (e.g., structured cell-ti ....3D Two-Photon Nanoprinter for Advanced Multi-Functional Materials & Devices. The Nanoscribe Photonic Professional GT2 Two-Photon 3D Printer enables tailoring materials’ architecture at nanoscale. This results in unique optical, mechanical, electrical, chemical, biochemical, and acoustic properties enabling a wealth of cutting-edge research activities in variety of fields including mechanical/optical/electrical metamaterials, bioinspired hard/soft materials, biomaterials (e.g., structured cell-tissue interfaces), biomedical devices (implantable devices and drug-delivery systems), nanofluidics, and photonic crystals. In each of these fields, we will use GT2 to print variety of polymers, hydrogels, metals and ceramics, for example by printing polymer-derived nanoceramics that will be simultaneously strong and tough.Read moreRead less
Bodies in space. By investigating how a change in shape of the human body can produce a change in spatial orientation, the project will bring a fundamental advance of knowledge in the intersection of applied mathematics, sports science and mechanical engineering. These knowledge advances will lead to a novel theory regarding the control of the aerial dynamics of athletes, specifically springboard and platform divers. When applied in collaboration with world class Australian athletes, this theory ....Bodies in space. By investigating how a change in shape of the human body can produce a change in spatial orientation, the project will bring a fundamental advance of knowledge in the intersection of applied mathematics, sports science and mechanical engineering. These knowledge advances will lead to a novel theory regarding the control of the aerial dynamics of athletes, specifically springboard and platform divers. When applied in collaboration with world class Australian athletes, this theory will result in innovative platform and springboard diving techniques and improved performance. The reach of new insights generated by this work extends to many other fields, including robotics, spacecraft dynamics and nano technology.Read moreRead less
Pressure waves on the mechanics of earthquakes and faulting. This project aims to decipher the physics of faulting and earthquakes from damage zones around seismogenic faults. It will examine a mechanism for instability in solids: volumetric collapse due to a dissipative pressure wave. This pressure wave may control damage-zone geometry and relate to earthquake stress and rock material properties. The project will research the instability through theoretical, laboratory and field studies. Antici ....Pressure waves on the mechanics of earthquakes and faulting. This project aims to decipher the physics of faulting and earthquakes from damage zones around seismogenic faults. It will examine a mechanism for instability in solids: volumetric collapse due to a dissipative pressure wave. This pressure wave may control damage-zone geometry and relate to earthquake stress and rock material properties. The project will research the instability through theoretical, laboratory and field studies. Anticipated outcomes include advances in earthquake and fault prediction, tools to determine the stress state and material properties of Earth’s crust, and knowledge of a class of solid instabilities.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE210100153
Funder
Australian Research Council
Funding Amount
$497,264.00
Summary
Integrated In situ Characterisation Facilities for Energy Studies. This project aims to establish a new capability to reveal catalytic behaviour of materials under practical working conditions at multi-scale levels. Through in situ monitoring of surface, interface and structural properties of catalysts, this unique integrated facility will overcome current limitations due to a lack of understanding of reaction mechanism, by ex situ and/or individual in situ characterisations. This world-class fa ....Integrated In situ Characterisation Facilities for Energy Studies. This project aims to establish a new capability to reveal catalytic behaviour of materials under practical working conditions at multi-scale levels. Through in situ monitoring of surface, interface and structural properties of catalysts, this unique integrated facility will overcome current limitations due to a lack of understanding of reaction mechanism, by ex situ and/or individual in situ characterisations. This world-class facility will significantly advance a range of electrocatalysis, photocatalysis and battery applications for renewable energy-storage and clean-fuel generation. This will be Australia’s only platform; it will benefit a number of innovative research projects in energy, catalysis and environmental and materials science.Read moreRead less