The role of intracellular calcium in fibre-type specific gene expression in skeletal muscle. Muscles contain different fibre types whose composition can be changed by activity. The aim of this proposal is to identify the intracellular mechanisms which control fibre type. Our hypothesis is that different patterns of intracellular calcium determine the pattern of gene expression which determines fibre type. Understanding how gene expression is regulated is a central issue in biology.
Intracellular calcium in intact muscle during fatigue and stretch-induced damage. Confocal microscopes can investigate intact tissues during normal function. We will develop and apply this novel approach to muscle. We expect this new approach to become a fundamental new tool for exploring muscle function under near normal conditions. Muscle pain and weakness are common disabilities in humans and we expect this new approach to provide insights into the causes and treatment of these common cond ....Intracellular calcium in intact muscle during fatigue and stretch-induced damage. Confocal microscopes can investigate intact tissues during normal function. We will develop and apply this novel approach to muscle. We expect this new approach to become a fundamental new tool for exploring muscle function under near normal conditions. Muscle pain and weakness are common disabilities in humans and we expect this new approach to provide insights into the causes and treatment of these common conditions.Read moreRead less
Modelling active play in preschool children using machine learning. This interdisciplinary project explores novel machine learning approaches to modelling physical activity data in preschool children. The approach taken is considered the future of physical activity assessment and is expected to substantially enhance the measurement of physical activity and the evidence base that informs strategies to improve population health through physical activity promotion. The project aims to transform the ....Modelling active play in preschool children using machine learning. This interdisciplinary project explores novel machine learning approaches to modelling physical activity data in preschool children. The approach taken is considered the future of physical activity assessment and is expected to substantially enhance the measurement of physical activity and the evidence base that informs strategies to improve population health through physical activity promotion. The project aims to transform the understanding of young children's physical activity behaviour, and is expected to have important implications for the design of accurate and effective technology-based physical activity monitoring and intervention applications that could be delivered through the e-health initiative in Australia.Read moreRead less
Engaging economically disadvantaged adolescent girls in physical activity and healthy eating to improve health and prevent obesity. Secondary school represents the final opportunity to influence individuals as they develop adult lifestyle behaviours and enter a transitional period in their lives. Considering the increased prevalence of lifestyle diseases among Australian adults and increases in the prevalence of obesity among young Australians, targeting health-promoting behaviours in adolescent ....Engaging economically disadvantaged adolescent girls in physical activity and healthy eating to improve health and prevent obesity. Secondary school represents the final opportunity to influence individuals as they develop adult lifestyle behaviours and enter a transitional period in their lives. Considering the increased prevalence of lifestyle diseases among Australian adults and increases in the prevalence of obesity among young Australians, targeting health-promoting behaviours in adolescents is clearly a national priority. Furthermore, rates of obesity are much higher in economically disadvantaged areas, with girls more susceptible to the SES disadvantages. This project has the potential to develop a knowledge base and improve the health behaviours of current and future Australians most at risk for the development of lifestyle diseases.Read moreRead less
Health-related physical activity: Psychological determinants, consequences, and experimental interventions. Increasingly sedentary lifestyles and physical inactivity constitute a worldwide health problem. Despite well-known benefits of physical activity, preventive-medicine interventions have had limited success. Instead, we propose an innovative psychological approach, emphasising quality of subjective experience (flow), motivation, physical self-concept, and the transtheoretical model of beha ....Health-related physical activity: Psychological determinants, consequences, and experimental interventions. Increasingly sedentary lifestyles and physical inactivity constitute a worldwide health problem. Despite well-known benefits of physical activity, preventive-medicine interventions have had limited success. Instead, we propose an innovative psychological approach, emphasising quality of subjective experience (flow), motivation, physical self-concept, and the transtheoretical model of behavioural change. We propose psychological determinants of physical activity and a new experimental intervention to significantly enhance health-related physical activity. The research breaks new theoretical ground, extending and integrating different theoretical perspectives, offering a synergy between qualitative and quantitative research traditions, and providing practical benefits to mental and physical health and to quality of life.Read moreRead less
Furthering Positive Futures for Children with Intellectual Disabilities: A Longitudinal Investigation. This project will address the paucity of empirical research on drivers of psychosocial and physical well-being (PPW; for example self-concept, depression, behavioural problems, physical fitness, weight) of children with Intellectual Disabilities (ID). This proposal presents an extensive research program aimed at understanding the effects of school life and Physical Activity (PA) on PPW for Aust ....Furthering Positive Futures for Children with Intellectual Disabilities: A Longitudinal Investigation. This project will address the paucity of empirical research on drivers of psychosocial and physical well-being (PPW; for example self-concept, depression, behavioural problems, physical fitness, weight) of children with Intellectual Disabilities (ID). This proposal presents an extensive research program aimed at understanding the effects of school life and Physical Activity (PA) on PPW for Australian children with ID. This program examines: the relations between school life and PPW; the benefits, barriers and predictors of PA; moderators (personal characteristics, educational settings). The overarching objective is to advance theory and research in this area, and to inform intervention strategies furthering more positive futures for children with ID.Read moreRead less
Taking risks with safety gear: Biomechanical and psychological perspectives on risk compensation. This project uniquely combines objective and subjective measures in investigating whether and how people take more risks in the face of safety interventions. Investigating changes in behaviour with safety gear in sport is of benefit because it (a) allows comprehensive measurement of risk-taking behaviour and (b) can result in significant health benefits. These health benefits include reducing sports ....Taking risks with safety gear: Biomechanical and psychological perspectives on risk compensation. This project uniquely combines objective and subjective measures in investigating whether and how people take more risks in the face of safety interventions. Investigating changes in behaviour with safety gear in sport is of benefit because it (a) allows comprehensive measurement of risk-taking behaviour and (b) can result in significant health benefits. These health benefits include reducing sports injuries through improving the efficacy of safety gear, and applications to risk-taking in other health domains, such as patient safety, occupational safety, and transport safety. Through improved methodology, the project should advance international research practice on this controversial topic.Read moreRead less
Psychological determinants of physical activity across the life span and critical life-stage transitions: Cross-sectional, longitudinal causal modelling, and experimental interventions. Increasingly, sedentary lifestyles and physical inactivity are major worldwide health problems. Despite well-established health benefits of physical activity, existing medical-oriented interventions have had limited effects on increasing population-levels of activity. We propose a psychological approach, emphasiz ....Psychological determinants of physical activity across the life span and critical life-stage transitions: Cross-sectional, longitudinal causal modelling, and experimental interventions. Increasingly, sedentary lifestyles and physical inactivity are major worldwide health problems. Despite well-established health benefits of physical activity, existing medical-oriented interventions have had limited effects on increasing population-levels of activity. We propose a psychological approach, emphasizing quality of subjective experience (flow), motivation, physical self-concept, and the transtheoretical model of change. We will evaluate psychological determinants of health-related physical activity and implement experimental physical activity enhancing interventions at two critical life stages: for late-adolescents and older Australians. The proposal advances theory and methodology in a National Research Priority area, providing practical solutions to important societal problems with socioeconomic benefits for Australia.Read moreRead less