Cortical Excitation In Migraine: Using Vision To Understand And Track Brain Excitability
Funder
National Health and Medical Research Council
Funding Amount
$521,628.00
Summary
Migraine is a common neurological condition affecting approximately 15% of adults. Therapies are most effective if used early, yet many people are unable to predict their migraines or to recognize early signs. In addition to headache, key symptoms include abnormal visual and auditory experience. We propose that aspects of vision and hearing will vary systematically according to the current brain status. Our translational goal is to develop tests that allow individuals to better manage migraine.
Although chronic pain is a serious clinical problem, treatments for its alleviation have largely failed, in part because they have not been tailored to the specific origin of the pain. This proposal focuses on rheumatoid arthritis, a common and incurrable source of chronic pain. This study will investigate how specific changes in spinal cord nerve cells contribute to chronic arthritic pain. The outcomes will help identify new targets to treat chronic pain in rheumatoid arthritis.