Complete blood fractionation using a low-cost microfluidic system. This project aims to understand particle focusing in inertial microfluidic systems to design efficient devices for cell sorting. The field of microfluidics could ultimately advance medical research but device design is primitive. Microfluidic particle separations are not thoroughly simulated before fabrication to predict performance. This project is expected to accelerate progress in design of efficient microfluidic devices. The ....Complete blood fractionation using a low-cost microfluidic system. This project aims to understand particle focusing in inertial microfluidic systems to design efficient devices for cell sorting. The field of microfluidics could ultimately advance medical research but device design is primitive. Microfluidic particle separations are not thoroughly simulated before fabrication to predict performance. This project is expected to accelerate progress in design of efficient microfluidic devices. The knowledge and models developed in this project should help design and develop a microfluidic device for efficient fractionation of complex fluids into valuable components.Read moreRead less
Personalised public transport. This project aims to address urban congestion by utilising people’s travel plans to coordinate journeys. The project expects to generate new knowledge in scalable optimisation, based on innovative modelling of urban transport, and tested on historical data from Melbourne. The expected outcomes of the project are an active transport database and optimised mode choice and routing system, with predicted reductions in congestion based on simulation of its use. This pro ....Personalised public transport. This project aims to address urban congestion by utilising people’s travel plans to coordinate journeys. The project expects to generate new knowledge in scalable optimisation, based on innovative modelling of urban transport, and tested on historical data from Melbourne. The expected outcomes of the project are an active transport database and optimised mode choice and routing system, with predicted reductions in congestion based on simulation of its use. This project aims to design an urban trip advisory system that could be followed by automated vehicles as well as human drivers, to reduce the financial and environmental cost of current urban congestion.Read moreRead less
Characterization of Fast Propagating Fires in Green Buildings. This project aims to gain a better understanding of the mechanisms of fast-propagating fires and to address the deficiency in current fire models in assessing the fire safety requirement of green buildings. Although there are many compelling advantages associated with green building designs, because they promote better natural ventilation they could pose a significant fire hazard to occupants due to the propensity of rapid fire and s ....Characterization of Fast Propagating Fires in Green Buildings. This project aims to gain a better understanding of the mechanisms of fast-propagating fires and to address the deficiency in current fire models in assessing the fire safety requirement of green buildings. Although there are many compelling advantages associated with green building designs, because they promote better natural ventilation they could pose a significant fire hazard to occupants due to the propensity of rapid fire and smoke spread within the enclosed space. The new predictive fire model in this project is expected to promote a safer and sustainable building environment.Read moreRead less
Building Australia's next-generation ocean-sea ice model. Ocean and sea ice models are used for predicting future ocean and climate states, and for climate process research. This project aims to bring the next generation of ocean-sea ice models to Australia and configure the models for our local priorities. The ultimate goal is to create a new coupled ocean-sea ice model for Australia that includes surface waves and biogeochemistry. The model will be optimised and evaluated on Australian facilit ....Building Australia's next-generation ocean-sea ice model. Ocean and sea ice models are used for predicting future ocean and climate states, and for climate process research. This project aims to bring the next generation of ocean-sea ice models to Australia and configure the models for our local priorities. The ultimate goal is to create a new coupled ocean-sea ice model for Australia that includes surface waves and biogeochemistry. The model will be optimised and evaluated on Australian facilities, and released for community use. These developments underpin future ocean state forecasts, sea ice forecasts, wave forecasts, decadal climate prediction and climate process studies. The project will benefit search and rescue, Defence and shipping operations, and will enhance future climate projections.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE210101549
Funder
Australian Research Council
Funding Amount
$395,775.00
Summary
A virtual platform for animal–human inhalation toxicity extrapolation. This project aims to remove the long-lasting barrier in extrapolating data from animals to humans by developing an integrated virtual platform. This project expects to fully resolve inhalation exposure differences in nasal airways between commonly used animal surrogates and humans, which could lay scientific underpinnings in developing rigorous interspecies data conversion schemes. Expected outcomes include a versatile inhala ....A virtual platform for animal–human inhalation toxicity extrapolation. This project aims to remove the long-lasting barrier in extrapolating data from animals to humans by developing an integrated virtual platform. This project expects to fully resolve inhalation exposure differences in nasal airways between commonly used animal surrogates and humans, which could lay scientific underpinnings in developing rigorous interspecies data conversion schemes. Expected outcomes include a versatile inhalation exposure risk assessment tool that can be implemented for any airway compartment, enhanced reliability of animal tests, reduced number of animals for testing. This should provide significant benefits in improving occupational health and safety and promoting National/International regulatory changes. Read moreRead less
The link between the deep Earth and its dynamic surface. Modelling the two-way interaction of plate tectonics with the actions of erosion and sedimentation gives a fundamentally new view of the dynamics of our planet and the importance of the surface on the deep interior. It will improve our understanding of the formation of sedimentary basins, their evolution and their preservation over geological time.
Decomposition and Duality: New Approaches to Integer and Stochastic Integer Programming. Because of their rich modelling capabilities, integer programs are widely used in industry for decision making and planning. However their solution algorithms do not have the maturity of their cousins in convex optimisation, where the theory of strong duality is ubiquitous. Efficient methods for convex optimisation under uncertainty do not apply to the integer case, which is highly non-convex. Furthermore, i ....Decomposition and Duality: New Approaches to Integer and Stochastic Integer Programming. Because of their rich modelling capabilities, integer programs are widely used in industry for decision making and planning. However their solution algorithms do not have the maturity of their cousins in convex optimisation, where the theory of strong duality is ubiquitous. Efficient methods for convex optimisation under uncertainty do not apply to the integer case, which is highly non-convex. Furthermore, integer models usually assume the data is known with certainty, which is often not the case in the real world. This project will develop new theory and algorithms to enhance the analysis of integer models, including those that incorporating uncertainty, while also enabling the use of parallel computing paradigms. Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE180101138
Funder
Australian Research Council
Funding Amount
$368,446.00
Summary
A multi-scale risk assessment platform for inhaled carbon nanotubes. This project aims to develop a coherent risk assessment platform to evaluate human respiratory exposure to carbon nanotubes. Compared to the exponential growth of carbon nanotubes technology, capability of inhalation risk assessment is lagging. The project expects to generate new knowledge on the unique role and risk of carbon nanotube geometry. It will develop a new transport model and create a unified risk assessment. The exp ....A multi-scale risk assessment platform for inhaled carbon nanotubes. This project aims to develop a coherent risk assessment platform to evaluate human respiratory exposure to carbon nanotubes. Compared to the exponential growth of carbon nanotubes technology, capability of inhalation risk assessment is lagging. The project expects to generate new knowledge on the unique role and risk of carbon nanotube geometry. It will develop a new transport model and create a unified risk assessment. The expected outcome is the enhanced risk assessment capability of human exposure to carbon nanotubes, which will provide a significant benefit to the nanotechnology industry through ensuring safety in developing an emergent technology.Read moreRead less