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Evolution of halophytes: a phyloinformatic approach to understanding and exploiting the traits underlying salt-tolerance in plants. Salinity is an increasing burden on the Australian economy & environment, with >2 million ha of salt-affected land, at an annual cost to agriculture over $187 million. One solution is to exploit naturally salt-tolerant plants to increase productive agricultural land and restore salt-affected environments. To do this, we must increase basic knowledge of the diversity ....Evolution of halophytes: a phyloinformatic approach to understanding and exploiting the traits underlying salt-tolerance in plants. Salinity is an increasing burden on the Australian economy & environment, with >2 million ha of salt-affected land, at an annual cost to agriculture over $187 million. One solution is to exploit naturally salt-tolerant plants to increase productive agricultural land and restore salt-affected environments. To do this, we must increase basic knowledge of the diversity & distribution of salt-tolerance. This project is the first to use DNA sequences from thousands of species to understand the evolution of salt-tolerance in order to provide the foundation for the development of new crop varieties, selection of species that can be developed for bioremediation, and identification of traits that will be profitable targets for breeding programs. Read moreRead less
Biogenesis of the relict plastid of Apicomplexan parasites: the role of a dynamin-related protein in apicoplast division. The Apicomplexa are a group of intracellular parasites that cause several important diseases. Most Apicomplexa contain an organelle called the apicoplast that is indispensable for their survival and that can only form through the division of pre-existing apicoplasts. This project will examine the molecular mechanisms of how this process occurs.
Discovery Early Career Researcher Award - Grant ID: DE200100500
Funder
Australian Research Council
Funding Amount
$414,089.00
Summary
The role of enemies in the generation of biodiversity. A fundamental question in biology is how new species are generated. The role of abiotic factors has been widely explored, but there is still little known about the role that ecological or behavioural interactions between organisms, such as parasitism or predation, play in the generation of diversity. This project aims to test the importance of anti-predator defences (warning colours) in generating species. It will combine micro- and macroevo ....The role of enemies in the generation of biodiversity. A fundamental question in biology is how new species are generated. The role of abiotic factors has been widely explored, but there is still little known about the role that ecological or behavioural interactions between organisms, such as parasitism or predation, play in the generation of diversity. This project aims to test the importance of anti-predator defences (warning colours) in generating species. It will combine micro- and macroevolutionary analyses to provide an in-depth test of this association. This project aims to provide a bridge between behavioural ecology and macroevolutionary processes, using Australian fauna, and increase our knowledge about whether and how enemies can contribute to generating diversity of life on earth.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE130100199
Funder
Australian Research Council
Funding Amount
$475,000.00
Summary
Establishment of the Protein Quantitation Centre of South Australia (PQCSA). Determining the protein quantities in culture cells, plant material, biological fluids and entire organisms will provide critical information regarding biological processes in plants and other organisms. The facility will allow the project to progress the understanding of complex biological systems.
Why is the photosynthetic CO2-fixing enzyme, Rubisco, so inefficient? Dissection of the catalytic chemistry by computational simulation and experimental testing. Fixation of CO2 by the enzyme Rubisco during photosynthesis produces organic compounds which feed all life. Despite this critical role, Rubisco catalyses its reaction sluggishly and, worse, discriminates poorly between CO2 and O2, leading to useless products. Our combined expertise equips us to analyse Rubisco's mechanism using quantum- ....Why is the photosynthetic CO2-fixing enzyme, Rubisco, so inefficient? Dissection of the catalytic chemistry by computational simulation and experimental testing. Fixation of CO2 by the enzyme Rubisco during photosynthesis produces organic compounds which feed all life. Despite this critical role, Rubisco catalyses its reaction sluggishly and, worse, discriminates poorly between CO2 and O2, leading to useless products. Our combined expertise equips us to analyse Rubisco's mechanism using quantum-chemical methods and then test predictions experimentally. We will capitalise on our previous successful studies of Rubisco by addressing emergent issues which are the keys to understanding catalytic efficiency and CO2/O2 selectivity: the roles of a carbamylated lysine; the way CO2 addition is rendered irreversible; and the spin inversion inherent in O2 addition.Read moreRead less
Conservation genomics of a critically endangered insect. This project aims to develop tools genotyping large animal genomes, focusing on the case of the Lord Howe Island stick insect, once thought to be extinct and now critically endangered. This project expects to generate molecular tools to monitor the genetic health the insect which has a large, complex and poorly understood genome. Expected outcomes include the development of a preservation and reintroduction strategy for the insect. This pr ....Conservation genomics of a critically endangered insect. This project aims to develop tools genotyping large animal genomes, focusing on the case of the Lord Howe Island stick insect, once thought to be extinct and now critically endangered. This project expects to generate molecular tools to monitor the genetic health the insect which has a large, complex and poorly understood genome. Expected outcomes include the development of a preservation and reintroduction strategy for the insect. This project will benefit ongoing conservation efforts, and is timely given the ongoing eradication of rats from Lord Howe Island where this species once lived. Read moreRead less
Biogenesis of red blood cell membrane modifications by the malaria parasite Plasmodium falciparum. Malaria is not only a major global health problem, but also affects countries neighbouring Australia like Indonesia, reducing the region's stability and prosperity. Environmental changes and increased mobility of people (aid and military personnel) make Australia itself more prone to malaria. The project will translate recent genomic data into functional insights using frontier technology to identi ....Biogenesis of red blood cell membrane modifications by the malaria parasite Plasmodium falciparum. Malaria is not only a major global health problem, but also affects countries neighbouring Australia like Indonesia, reducing the region's stability and prosperity. Environmental changes and increased mobility of people (aid and military personnel) make Australia itself more prone to malaria. The project will translate recent genomic data into functional insights using frontier technology to identify new intervention targets for Plasmodium falciparum infection. Developing novel targets is mandated by humanity, but also to safeguard Australia's region against the social and economic implications of this disease. An Australian developed intervention would increase the global visibility of its science, leading to increased investments.Read moreRead less
Hybridisation leading to lost sex: genomic and experimental insights. The project intends to apply advanced genomics to two classic Australian systems and quantitative genetics to one to address long-standing questions about why asexual reproduction is rare. It aims to test for rapid changes in genomes accompanying hybrid-origins of asexuals and whether this new diversity enables their ongoing evolution. The significance is that support for this hypothesis would challenge current theory for why ....Hybridisation leading to lost sex: genomic and experimental insights. The project intends to apply advanced genomics to two classic Australian systems and quantitative genetics to one to address long-standing questions about why asexual reproduction is rare. It aims to test for rapid changes in genomes accompanying hybrid-origins of asexuals and whether this new diversity enables their ongoing evolution. The significance is that support for this hypothesis would challenge current theory for why sex is so common. The expected outcome is to understand how variation is generated in natural populations with different ways of reproducing. Benefits would include significant contributions to global science, evolutionary training and potential applications in using hybridisation to manage threatened species or pests.Read moreRead less
ARC Research Network for Advanced Materials. Materials science/engineering is decidedly interdisciplinary, covering all science and impacting on all manufacturing industry. This network will promote interactions that do not usually occur between materials researchers and students across Australia and internationally from diverse disciplines. The scope is broadly based on advanced materials production, processing and properties but focused in four areas, involving: i) innovative structural/functi ....ARC Research Network for Advanced Materials. Materials science/engineering is decidedly interdisciplinary, covering all science and impacting on all manufacturing industry. This network will promote interactions that do not usually occur between materials researchers and students across Australia and internationally from diverse disciplines. The scope is broadly based on advanced materials production, processing and properties but focused in four areas, involving: i) innovative structural/functional materials, ii) high-tech IT/communications/sensing materials, iii) materials solutions for manufacturing, iv) materials for a sustainable Australia, and v) emerging materials technologies. Key programs will promote interdisciplinary workshops and early career researcher interactions.Read moreRead less
Special Research Initiatives - Grant ID: SR0354512
Funder
Australian Research Council
Funding Amount
$30,000.00
Summary
Network Asia: Maximizing Australia's National Capacity in Inter-Disciplinary Research on Asia. Australia has an international reputation for innovative and high impact research into the states, societies, and economies of Asia.
The Initiative will survey the volume, range, impact, and international status of Asian area research in Australia, identify themes with high potential for achieving significant outcomes through transnational research and research-training, and develop a strategy for m ....Network Asia: Maximizing Australia's National Capacity in Inter-Disciplinary Research on Asia. Australia has an international reputation for innovative and high impact research into the states, societies, and economies of Asia.
The Initiative will survey the volume, range, impact, and international status of Asian area research in Australia, identify themes with high potential for achieving significant outcomes through transnational research and research-training, and develop a strategy for maximizing national research capacity in targeted areas through a national inter-disciplinary network for Asia-area research - Network Asia.
Outcomes include a published report on the state of the field and a strategic plan for a viable and sustainable research network.
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