The Epigenetics of Sex in the Dragon. Genetic codes do not directly translate to phenotypes -- environment acts through epigenetics to modify development. We use advanced molecular techniques to examine how epigenetics responds to temperature to reverse sex in our novel animal model, the dragon lizard. How does the cell sense temperature? Once the extrinsic signal is captured, how does it influence chromatin modification to release or suppress key genes in the sex differentiation pathway? Which ....The Epigenetics of Sex in the Dragon. Genetic codes do not directly translate to phenotypes -- environment acts through epigenetics to modify development. We use advanced molecular techniques to examine how epigenetics responds to temperature to reverse sex in our novel animal model, the dragon lizard. How does the cell sense temperature? Once the extrinsic signal is captured, how does it influence chromatin modification to release or suppress key genes in the sex differentiation pathway? Which sex genes are targets? Epigenetic enzymes are astonishingly conserved, providing exciting opportunities to draw from human systems to unravel novel signatures of temperature-induced sex switching in reptiles. This project will advance knowledge of developmental programming generally.Read moreRead less
How do qualifications delivered by enterprises contribute to improved skill levels and other benefits for companies, workers and the nation? This project investigates the role of employer-based qualifications training in developing the skills and prospects of the Australian workforce and the competitive capabilities of companies. It focuses on enterprises that are accredited to deliver qualifications to their own workers, providing data to improve and expand this form of training.
Exemplary early childhood educators at work: A multi-level investigation. Exemplary early childhood educators at work: A multi-level investigation. This project aims to inform strategies to better attract, prepare, recognise, support and retain a high quality workforce, by investigating the complexity of early childhood educators’ work. Seemingly entrenched workforce shortages threaten the objectives that governments and families seek through investment in early childhood education. Popular imag ....Exemplary early childhood educators at work: A multi-level investigation. Exemplary early childhood educators at work: A multi-level investigation. This project aims to inform strategies to better attract, prepare, recognise, support and retain a high quality workforce, by investigating the complexity of early childhood educators’ work. Seemingly entrenched workforce shortages threaten the objectives that governments and families seek through investment in early childhood education. Popular images of work with young children as easy and instinctual, or of teaching as only school based, mislead potential workforce entrants and erode the status of educators, leading to attrition. This project’s audit and description of exemplary educators’ work, across each level of mandated qualification, will inform strategies to sustain a high quality early childhood workforce into the future.Read moreRead less
ARC Centre of Excellence for Children and Families over the Life Course. New solutions are needed to underpin the Australian social ideal of a fair go, and to drive future global economic productivity. The Australian Productivity Commission identifies deep and persistent disadvantage as a significant problem in Australia given the failure of growing national prosperity over the past two decades to benefit underprivileged Australians. Social disadvantage is a global challenge. This Centre will ad ....ARC Centre of Excellence for Children and Families over the Life Course. New solutions are needed to underpin the Australian social ideal of a fair go, and to drive future global economic productivity. The Australian Productivity Commission identifies deep and persistent disadvantage as a significant problem in Australia given the failure of growing national prosperity over the past two decades to benefit underprivileged Australians. Social disadvantage is a global challenge. This Centre will advance basic, applied and translational research to reduce intergenerational and long-term disadvantage. Through the maturation of longitudinal datasets and advanced data integration we can follow the journeys of Australian families over generations and across the life course. This data will provide evidence for new policies and make a real difference to the lives of children and families.Read moreRead less
Female roles during postcopulatory sexual selection. The project will evaluate the importance of postcopulatory sexual selection in the guppy, a polyandrous species of livebearing fish. The use of artificial insemination, which experimentally controls the relative contribution of sperm from competing males (as well as other confounding effects), will facilitate a powerful test of recent theoretical predictions in evolutionary biology. The project will enable me to distinguish between competing h ....Female roles during postcopulatory sexual selection. The project will evaluate the importance of postcopulatory sexual selection in the guppy, a polyandrous species of livebearing fish. The use of artificial insemination, which experimentally controls the relative contribution of sperm from competing males (as well as other confounding effects), will facilitate a powerful test of recent theoretical predictions in evolutionary biology. The project will enable me to distinguish between competing hypotheses for postcopulatory paternity bias following female multiple mating (sperm competition, cryptic female choice, genetic compatibility) and provide additional insights into the selective forces promoting the evolution of female promiscuity.Read moreRead less
New digital deep-time exploration tools for a low-emissions economy. Demand for critical minerals will soar as renewable energy generation increases, but exploration companies currently cannot take full advantage of available exploration data in an Earth evolution context. This project will generate new knowledge in big and complex geodata analysis using an innovative data mining approach. It will enable Lithodat, a small enterprise, to perform cloud-based plate tectonic reconstruction, visualis ....New digital deep-time exploration tools for a low-emissions economy. Demand for critical minerals will soar as renewable energy generation increases, but exploration companies currently cannot take full advantage of available exploration data in an Earth evolution context. This project will generate new knowledge in big and complex geodata analysis using an innovative data mining approach. It will enable Lithodat, a small enterprise, to perform cloud-based plate tectonic reconstruction, visualisation and spatio-temporal analysis of geodata for resource exploration. The outcomes include an enhanced capacity to generate ore prospectivity maps and an improved understanding of their tectonic, geochemical, and geophysical signatures, benefiting Lithodat and their clients in the search for new mineral deposits.Read moreRead less
Sex determination in dragons: Genetics, epigenetics and environment. This project aims to discover the master sex-determining gene in a reptile, how that gene is differentially regulated in males and females and by temperature, and to identify evolutionary drivers of transitions between genetic and environmental sex determination. In many reptiles, like mammals, chromosomes determine sex. In others, the temperature at which their eggs are incubated determines sex. This project will study how tem ....Sex determination in dragons: Genetics, epigenetics and environment. This project aims to discover the master sex-determining gene in a reptile, how that gene is differentially regulated in males and females and by temperature, and to identify evolutionary drivers of transitions between genetic and environmental sex determination. In many reptiles, like mammals, chromosomes determine sex. In others, the temperature at which their eggs are incubated determines sex. This project will study how temperature reverses chromosomal sex determination in dragon lizards. This could show how climatic extremes affect the biology of climate sensitive reptiles, and understand their vulnerability to climate change.Read moreRead less
Special Research Initiatives - Grant ID: SR0354729
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
Smart Use of Information Technologies (SUITs). The SUITs network will develop critical mass in world-class, leading-edge research into the smart use of information and communication technology (ICT) through integration of research within the dispersed Australian ICT research community and through facilitating international linkages. The network will undertake research applicable in key sectors including the health, education, service, knowledge and media industries. The aim is to establish a h ....Smart Use of Information Technologies (SUITs). The SUITs network will develop critical mass in world-class, leading-edge research into the smart use of information and communication technology (ICT) through integration of research within the dispersed Australian ICT research community and through facilitating international linkages. The network will undertake research applicable in key sectors including the health, education, service, knowledge and media industries. The aim is to establish a higher order of coordination and collaboration in research into ICT applications.
The feasibility study proposed will engage key stakeholders, refine research goals and investigate linkage mechanisms to improve Australia's ICT research and its contribution to economic and social well-being.
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Speech production in language-impaired speakers: Informing theoretical models and clinical practice regarding grammatical processing. This research examines how language is stored and processed in our minds and the ways this can go wrong. By improving our theory of language processing, the research will result in improved diagnosis and treatment for the ten per cent of Australians who suffer from communication impairment.
Controlling coastlines while generating power. The Project aims to produce strategies for protecting coasts from storms using farms of wave-energy machines, which also generate electricity. Increasing lengths of coast need protection as the climate changes, but conventional barriers create permanent environmental impacts and are a sunk cost usually borne by the taxpayer. The Project expects to derive a strategy for the setting of each machine in the farm, so that they collectively absorb or refl ....Controlling coastlines while generating power. The Project aims to produce strategies for protecting coasts from storms using farms of wave-energy machines, which also generate electricity. Increasing lengths of coast need protection as the climate changes, but conventional barriers create permanent environmental impacts and are a sunk cost usually borne by the taxpayer. The Project expects to derive a strategy for the setting of each machine in the farm, so that they collectively absorb or reflect damaging waves under severe conditions. Under normal conditions, enough wave energy to sustain environmental processes would pass through. Sales of electricity would help to pay back the capital cost. Outcomes would include reduced coastal-erosion costs and a low-intermittency energy supply.Read moreRead less