An In Depth Analysis Of Clinical And Virological Outcomes Of 2 Strategies For The Antiretroviral Salvage Of First-line Regimen Virological Failure For HIV-1 Infection Tested In An Australian-led Randomised, International, Multi-centre Clinical Trial
Funder
National Health and Medical Research Council
Funding Amount
$421,747.00
Summary
The recently completed Australian-led SECOND-LINE trial is the first high quality study to provide reliable evidence for policy recommendations for the composition of anti-HIV drug cocktails after standard initial treatment has failed. This award will support the researcher in further refining our understanding of how to manage second-line therapy including proposals to test the use of low-cost technologies for application in resource-limited settings where the majority of people with HIV live.
Improving Insect-based Technology for Minimum Death Time Estimates in Forensic Investigations in Australia. This research will provide more accurate, narrower death time estimates for Australia. Focusing enquiries more accurately around the death time will result in significant financial savings in homicide investigations. Court evidence based on insects will become more robust, thus improving prosecution success. Partnerships will also be enhanced between laboratories with common aims, but di ....Improving Insect-based Technology for Minimum Death Time Estimates in Forensic Investigations in Australia. This research will provide more accurate, narrower death time estimates for Australia. Focusing enquiries more accurately around the death time will result in significant financial savings in homicide investigations. Court evidence based on insects will become more robust, thus improving prosecution success. Partnerships will also be enhanced between laboratories with common aims, but different experience and expertise, thereby avoiding research duplication and producing synergistic effects of collaboration. Casework methodology in Australia will become better aligned, thus avoiding courtroom conflicts between practitioners. Finally, high quality graduate students will be trained in entomological and forensic sciences.Read moreRead less
Can and should we link data at a national level? Vaccine safety surveillance: A case study. This project provides many benefits for the community, exploring the legal and ethical issues around consent for data linkage, convening Citizens' Juries to weigh the evidence and make recommendations. It addresses National Research Priorities: Promoting and Maintaining Good Health and Safeguarding Australia as well as National Collaborative Research Infrastructure Strategy priorities. It uses vaccine sa ....Can and should we link data at a national level? Vaccine safety surveillance: A case study. This project provides many benefits for the community, exploring the legal and ethical issues around consent for data linkage, convening Citizens' Juries to weigh the evidence and make recommendations. It addresses National Research Priorities: Promoting and Maintaining Good Health and Safeguarding Australia as well as National Collaborative Research Infrastructure Strategy priorities. It uses vaccine safety surveillance as a case study to evaluate the effectiveness of data linkage (through linking Commonwealth immunisation data to state hospital data) and the methodologies and lessons learnt from cross jurisdictional data linkage can be transferred to other areas. Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE130100127
Funder
Australian Research Council
Funding Amount
$400,000.00
Summary
Controlled radiation facility to investigate turbulence-radiation-chemistry interactions in high-flux solar reactors. This project's facility will support the transition of Australia’s energy intensive industries, including minerals and resources, to a much lower carbon intensity. It will also underpin collaborations with internationally leading partners to develop novel solar-combustion hybrid reactors for the production of solar fuels and for minerals processing.
Development and evaulation of novel foods enriched with very long chain omega-3 fatty acids. This project is a collaborative effort between Meadow Lea Foods, Clover Corporation, and the Universities of Wollongong and Western Australia. The aims are 1) to develop a range of functional foods enriched with omega-3 from tuna oil; 2) to see whether the recommended omega-3 intake, currently nor met by most Australians, can be achieved by including these foods in the diet; 3) to evaluate sensory and he ....Development and evaulation of novel foods enriched with very long chain omega-3 fatty acids. This project is a collaborative effort between Meadow Lea Foods, Clover Corporation, and the Universities of Wollongong and Western Australia. The aims are 1) to develop a range of functional foods enriched with omega-3 from tuna oil; 2) to see whether the recommended omega-3 intake, currently nor met by most Australians, can be achieved by including these foods in the diet; 3) to evaluate sensory and health attributes and other factors that may impact on consumer acceptability hence market potential of the food range. There is little evidence of the feasibility let alone health and social benefits of utilising novel foods to meet the dietary omega-3 recommendation. We expect a) to show how consumers could benefit by using a range of such foods in their customary diet; b) to critically set this achievement within the context of current social trends in food product development. Read moreRead less
Implementing guidelines to prevent chronic disease in the community. The burden of chronic disease in Australia has resulted in prevention of chronic disease being an important priority for the Australian health system. High quality evidence for preventing chronic disease exists; however the practice falls short of the evidence. Finding ways to implement the evidence for preventing chronic disease is an urgent national need. This study aims to apply the evidence for preventing chronic disease in ....Implementing guidelines to prevent chronic disease in the community. The burden of chronic disease in Australia has resulted in prevention of chronic disease being an important priority for the Australian health system. High quality evidence for preventing chronic disease exists; however the practice falls short of the evidence. Finding ways to implement the evidence for preventing chronic disease is an urgent national need. This study aims to apply the evidence for preventing chronic disease in practice. It will generate data and validate a model on how to effectively improve the uptake of guidelines by both practitioners and consumers. This project is of national and community benefit because it will enable the potential of preventing chronic disease to be realised.Read moreRead less
Skin penetration of nanoparticles promoted by particle design, formulation and application method. This project seeks to better define the determinants of nanoparticle skin penetration and subsequent disposition in the body. The data would be used to guide minimal skin penetration of 'undesirable' nanoparticles and the properties required of 'safe' nanoparticles to enable effective human skin delivery in cosmetic and dermatological products.
Access to mobile communications for older people with impairments. This research will determine the potential to use mobile communications to enable older people with impairments to remain active members of the community. it will test the capacity for mobiles to enable:
* older people with impairments to maintain social communication links and summon assistance; and
* caregivers to maintain contact with the older person during the day.
Providing these capabilities has the potential to improve ....Access to mobile communications for older people with impairments. This research will determine the potential to use mobile communications to enable older people with impairments to remain active members of the community. it will test the capacity for mobiles to enable:
* older people with impairments to maintain social communication links and summon assistance; and
* caregivers to maintain contact with the older person during the day.
Providing these capabilities has the potential to improve the wellbeing and confidence of older people with impairments and their caregivers and to reduce negative outcomes due to falls or other medical problems by enabling older people to summon assistance easily.Read moreRead less
The Norfolk Island Carbon and Health Evaluation Program: a case study of personal carbon trading for reducing obesity and greenhouse gas emissions. This project tests a system of Personal Carbon Trading for reducing greenhouse gas emissions and improving health. Carbon credit cards given to everyone on Norfolk Island are designed to financially reward people for reducing energy use (fuel and fatty food mainly) by increasing walking/cycling and improving nutrition to improve health
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE160100026
Funder
Australian Research Council
Funding Amount
$230,000.00
Summary
VetCompass: Big Data and Real-time Surveillance for Veterinary Science. VetCompass: big data and real-time surveillance for veterinary science:
The VetCompass data service intends to collect real-time records from veterinary clinics and aggregate them for researchers to interrogate. It aims to provide Australian researchers with sustainable and cost-effective access to authoritative data from hundreds of practitioners in Australia and the United Kingdom. These data will be essential for researc ....VetCompass: Big Data and Real-time Surveillance for Veterinary Science. VetCompass: big data and real-time surveillance for veterinary science:
The VetCompass data service intends to collect real-time records from veterinary clinics and aggregate them for researchers to interrogate. It aims to provide Australian researchers with sustainable and cost-effective access to authoritative data from hundreds of practitioners in Australia and the United Kingdom. These data will be essential for research on disease distribution and determinants, and surveillance and diagnostics that underpin evidence-based practice. The expected outcomes include identification of the most prevalent disorders and their causes and optimal treatments. The data may also revolutionise clinical auditing in Australia, help the veterinary profession to rank research priorities, and inform companion animal and equine curricula in our universities.Read moreRead less