Evaluation Of SCID-I In The Diagnosis Of Mental Disorders In Indigenous Australians
Funder
National Health and Medical Research Council
Funding Amount
$988,007.00
Summary
Current estimates of mental disease among Indigenous Australians are inadequate. This research will examine the use of a structured interview tool that is promoted globally for diagnosing mental disorders, and then use the tool to quantify the burden of mental illness among Indigenous Australians. The findings will provide accurate estimates of occurrence of mental disorders, thereby help inform policy making and planning of services for Indigenous Australians.
Is Lactic Acid Concentration In Amniotic Fluid A New Predictor Of Labour Dystocia?
Funder
National Health and Medical Research Council
Funding Amount
$682,538.00
Summary
This study will establish whether higher concentrations of lactate in the amniotic fluid of labouring women can be used as a surrogate marker to improve diagnoses of presence or absence of dystocia. Labour dystocia is a serious problem experienced during childbirth, and is one of the main indications for emergency caesarean section or forceps or vacuum delivery. Although dystocia is a common clinical problem, the current lack of a precise definition leads to considerable variation in practice.
Using Collaboration Networks To Measure Bias And Inefficiency In The Production And Translation Of Evidence About Cardiovascular Risk
Funder
National Health and Medical Research Council
Funding Amount
$219,806.00
Summary
Doctors rely on clinical trials comparing the safety and efficacy of cardiovascular treatments but are often unable to find or trust the information they seek because of problems in evidence translation. This project will examine the networks of collaboration amongst researchers and their research to identify the source of these problems. The research will be used to identify where to intervene in the process, in turn helping doctors to make safe and cost-effective decisions for their patients.
SEA-URCHIN: South East Asia - Using Research For Change In Hospital-acquired Infection In Neonates
Funder
National Health and Medical Research Council
Funding Amount
$2,303,773.00
Summary
Each year, more than one million babies die from infection before they reach one month of age. Proven and inexpensive practices to prevent and treat infection exist but they are not always followed (eg hand washing). This research will evaluate the impact of tailored implementation strategies on rates of infection and death in the neonatal units of nine hospitals in four counties in South East Asia. Staff from these units will work with Australian partners to devise, implement and evaluate diffe ....Each year, more than one million babies die from infection before they reach one month of age. Proven and inexpensive practices to prevent and treat infection exist but they are not always followed (eg hand washing). This research will evaluate the impact of tailored implementation strategies on rates of infection and death in the neonatal units of nine hospitals in four counties in South East Asia. Staff from these units will work with Australian partners to devise, implement and evaluate different strategies.Read moreRead less
How Should We Analyse, Synthesize, And Interpret Evidence From Interrupted Time Series Studies? Making The Best Use Of Available Evidence
Funder
National Health and Medical Research Council
Funding Amount
$445,144.00
Summary
Interrupted time series (ITS) studies are frequently used to evaluate whether policy interventions are successful. The findings from these studies are often collated into systematic reviews, which are used to inform healthcare decisions by clinicians, consumers and policy makers. It is not known how the statistical methods, which underpin the findings from ITS studies, perform. This proposal will evaluate the statistical methods and provide guidance on how to analyse and interpret ITS studies.
Enabling Personalised Cohort Studies From Large Repositories Of Clinical Practice Data
Funder
National Health and Medical Research Council
Funding Amount
$520,968.00
Summary
We propose to leverage the information contained in large, routinely collected health datasets, by enabling personalised cohort studies on demand. Findings from these studies can be used to crowdsource prioritisation of clinical questions in need of further evidence. They can also provide an avenue to discuss and support treatment recommendations at the point-of-care.
The SAVE Trial: Securing All IntraVenous Devices Effectively In Hospitals. A Randomised Controlled Trial
Funder
National Health and Medical Research Council
Funding Amount
$980,393.00
Summary
Going to hospital usually means having an IV drip in your hand or arm vein. Almost half of all IV drips fall out or fail because they are not well secured to the skin. This means patients miss out on treatment and have additional painful needlesticks to insert new devices. Serious infections can also occur. This study will find the best dressings to use on IV drips. Patients will have their drips glued in with medical superglue, or have one of two new dressings, compared with current usual care.
Preventing Depression And Reducing The Impact Of Aphasia In Stroke Patients And Their Caregivers A Year Post Onset Via A Brief Early Intervention: A Cluster Randomised Control Trial Of The Action Success Knowledge (ASK) Program.
Funder
National Health and Medical Research Council
Funding Amount
$1,327,820.00
Summary
Loss of language after stroke (aphasia) leads to problems with understanding, talking, reading and writing. Aphasia often leads to depression and poorer wellbeing for the person with aphasia and the caregiver. Our research has a) identified what it takes to live successfully with aphasia, b) translated the results to a program called ASK, and c) piloted ASK with promising outcomes in reducing symptoms of depression. We will measure the impact of ASK at 12 month post stroke.
Does Gastrostomy Improve The Lives Of Children With Severe Disability And Their Families?
Funder
National Health and Medical Research Council
Funding Amount
$645,101.00
Summary
Around 750 Australian children are born each year with severe intellectual disability. Problems may include feeding difficulties and frequent hospitalisations. Feeding via a gastrostomy tube into the stomach can be used. We will conduct a data linkage study in NSW and WA, and collect additional data in WA to investigate patterns of gastrostomy use and its safety, effectiveness and costs. Our findings will help the management of poor feeding in intellectual disability.
Venesection Or Expectant Management For Moderate Iron Overload In HFE Related Hereditary Haemochromatosis
Funder
National Health and Medical Research Council
Funding Amount
$853,109.00
Summary
Haemochromatosis is a preventable genetic iron overload disorder. Untreated, it can shorten life due mainly to liver cirrhosis and cancer. It can be prevented by blood donation to maintain normal iron levels. It is unclear, however, whether treatment is necessary when individuals have moderate elevation of iron in the body. This research project will study the effects of treatment in this group by assessing a number of scans, questionnaires and blood tests in treated and untreated individuals.