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Regulating Autologous Stem Cell Therapies in Australia. This project aims to develop an ethical and regulatory framework for the use of autologous adult stem cell therapies in Australia. These therapies are increasingly being offered to patients for diseases and conditions that lack scientific evidence of safety and efficacy. This study aims to address this problem using a mixed methods approach to generate empirical data and theoretical, ethical and legal insights that will guide the responsibl ....Regulating Autologous Stem Cell Therapies in Australia. This project aims to develop an ethical and regulatory framework for the use of autologous adult stem cell therapies in Australia. These therapies are increasingly being offered to patients for diseases and conditions that lack scientific evidence of safety and efficacy. This study aims to address this problem using a mixed methods approach to generate empirical data and theoretical, ethical and legal insights that will guide the responsible development, translation and regulation of innovative stem cell therapies in Australia and internationally. Anticipated outcomes will improve patient advocacy and public knowledge about adult stem cell therapies, and facilitate better relationships between patients, researchers and clinicians.Read moreRead less
Socially Responsible Insurance in the Age of Artificial Intelligence. This project aims to discover the social costs and benefits of using Artificial Intelligence in insurance, and to design practical interventions—responsible design workshops, practical guidance, regulatory proposals, new algorithmic tools—that realise the benefits while mitigating the costs. It expects to generate new knowledge drawing on philosophy, law and sociology, working closely with practitioners at the forefront of dep ....Socially Responsible Insurance in the Age of Artificial Intelligence. This project aims to discover the social costs and benefits of using Artificial Intelligence in insurance, and to design practical interventions—responsible design workshops, practical guidance, regulatory proposals, new algorithmic tools—that realise the benefits while mitigating the costs. It expects to generate new knowledge drawing on philosophy, law and sociology, working closely with practitioners at the forefront of deploying AI in insurance. Expected outcomes include novel ethical AI-based approaches to product design, pricing and claims administration. This should benefit insurers and consumers, realising efficiency gains made possible by AI, without unacceptable costs to privacy, fairness, and the unaccountable exercise of power. Read moreRead less
Changing your mind by changing your brain: An interventionist perspective on cognitive neuroscience. Functional neuroimaging provides a tremendous amount of information about the brain, but what it shows about the mind is less clear. Addressing this fundamental philosophical question requires developing a detailed account of theory-testing in cognitive neuroscience. This project aims to connect neuroimaging to theories of explanation that focus on the way one variable can make a difference to an ....Changing your mind by changing your brain: An interventionist perspective on cognitive neuroscience. Functional neuroimaging provides a tremendous amount of information about the brain, but what it shows about the mind is less clear. Addressing this fundamental philosophical question requires developing a detailed account of theory-testing in cognitive neuroscience. This project aims to connect neuroimaging to theories of explanation that focus on the way one variable can make a difference to another. By linking neuroimaging to facts about manipulable relationships between the brain and the mind, it will also provide a bridge between neuroimaging and complementary technologies for directly intervening on the brain. This, in turn, will provide a platform from which to explore the theoretical and ethical consequences of direct brain manipulation.Read moreRead less
Global Citizen Deliberation: Analysing a Deliberative Documentary. The project will enact and film the world’s first truly global citizens’ deliberation, a global citizens’ assembly (GCA) on genome editing, and proceed to analyse the impact of the ‘deliberative documentary’ film on public understanding of complex, fast-evolving science and technology. It will investigate the cross-cultural capacity of citizens to deliberate complex value-laden issues, and so ascertain prospects for an informed g ....Global Citizen Deliberation: Analysing a Deliberative Documentary. The project will enact and film the world’s first truly global citizens’ deliberation, a global citizens’ assembly (GCA) on genome editing, and proceed to analyse the impact of the ‘deliberative documentary’ film on public understanding of complex, fast-evolving science and technology. It will investigate the cross-cultural capacity of citizens to deliberate complex value-laden issues, and so ascertain prospects for an informed global public response to challenges posed by genome editing. Research will test the effects of the deliberative documentary on viewers, examining benefits of communicating complex issues via the work of the GCA. Other benefits include improving public trust in governance and advancing the Australian film industry.
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Electrophoretic Identification Of Fish Species Or Salmon On Friday But Barramundi
Funder
Fisheries Research and Development Corporation
Summary
Objectives: 1. Investigate the characteristic banding patterns of fish proteins obtained by electrophoresis with a view to establishing a library of identification for Australian species
Objectives: 1. To assess the feasibility of capturing live SBT in a state from which they can survive under agistment conditions 2. To grow out SBT in pontoons in the Port Lincoln area to assess: growth rates, total and in specivic period, feed conversion ratios, preferred feeds 3. To assess the influence of the SBT grow out on the environment with water quality testing by the SA Government 4. To assess the quality and market acceptance of farmed SBT 5. To provide an ....Objectives: 1. To assess the feasibility of capturing live SBT in a state from which they can survive under agistment conditions 2. To grow out SBT in pontoons in the Port Lincoln area to assess: growth rates, total and in specivic period, feed conversion ratios, preferred feeds 3. To assess the influence of the SBT grow out on the environment with water quality testing by the SA Government 4. To assess the quality and market acceptance of farmed SBT 5. To provide an example for other pontoon culturing or farming in Australia 6. To examine the possibility of breeding SBT 7. To provide a basis for sustainable biological research (eg Otoliths) Read moreRead less
SCRC: SCRC RTG: Collaboration With Dr Salina Parveen To Discuss Comparisons Of Vibrio Parahaemolyticus Models For Australian Pacific, Sydney Rock, And American Oysters At The University Of Maryland (for Mark Tamplin)
Aquaculture Nutrition Subprogram: Assessment Of Growth Performance Under Limiting Environmental Conditions
Funder
Fisheries Research and Development Corporation
Funding Amount
$466,788.00
Summary
The research proposed here has received consistantly strong support from the TSGA, The TasFRAB, the Atlantic Salmon Aquaculture Subprogram and the Aquaculture Nutrition Subprogram. The research addresses two Challenges in the FRDC R&D Plan 2000-2005: Challenge 2 Increasing production through aquaculture (FRDC R&D Plan 2000-2005) is addrssed by this research. The research proposed contributes by increasing understanding of how to increase production under Australian environmental conditions ....The research proposed here has received consistantly strong support from the TSGA, The TasFRAB, the Atlantic Salmon Aquaculture Subprogram and the Aquaculture Nutrition Subprogram. The research addresses two Challenges in the FRDC R&D Plan 2000-2005: Challenge 2 Increasing production through aquaculture (FRDC R&D Plan 2000-2005) is addrssed by this research. The research proposed contributes by increasing understanding of how to increase production under Australian environmental conditions and how to increase efficiency. Challenge 5 Reducing the quality of fish protein fed to aquatic livestock (FRDC R&D Plan 2000-2005). The proposed research contributes by increasing understanding of processes that drive growth efficiency.
It must be stressed that the research proposed here has been developed in collaboration with Skretting and this means that results will impact on aquafeeds rapidly and in a meaningful way. However, the data generated will be disseminated for use by other feed manufacturers, the aquaculture industry and other researchers.
Tactical Needs The proposed research aims to demonstrate which feeds are most appropriate for use at the different temperatures experienced by both the salmon and barramunid aquaculture industry during the normal production cycles and over the geographical range they are farmed. The research has to be conducted in Australia because the performance of Atlantic salmon at high temperatures is not important in Northern Europe and the performance of barramundi at low temperatures important is not relevant in South East Asia. Consequently, it is unlikely that commercially driven research of relevance to Australian conditions will be conducted outside of Australia. The vital importance of understanding the relationship between dietary protein and energy in relation to temperature and low growth has been very clearly identified by individual Salmonid growers and by the TSGA for several years. However, farm data cannot be used to solve the issues retrospectively and a clear need for controlled experiments exists. Barramundi aquaculture is expanding rapidley across Australia and they are being farmed under many different environmental (temperature) regimes, there is a clear need to understand the relationship between dietary protein and energy in relation to temperature. In addition to providing direct information about the performance of both species of fish in relation to diet composition the experiments are designed so that data can be incorporated into "factorial models" of growth. These are used by feed companies as well as under development by key researchers. The proposed research will make an important contribution to the data base for these and for both species.
Strategic Needs The research seeks to address the lack of information about mechanisms that determine efficient growth in fish by consideration key physiological and nutritional variables in relation to temperature. The PI has an extensive record of uses physiological tools to investigate amino acid (protein) and energy utilisation by fishes. Developing this approach in realtion to temperature is of strategic importance for equiping Australian aquaculture with tools to investigate other species. Protein synthesis is a major driver of growth but it is energetically expensive (20-40% of costs of growth)and understanding the interaction between diet composition and efficient growth is a major driver behind the proposed research. The research will develop physiological tools using barramundi as a model, these will then be tested and deveoped further using salmon. Objectives: 1. Generate critically identified data for incorporation into factorial growth models that describe nutrient supply and nutrient retention in relation to temperature. 2. Determine the optimum dietary protein to energy ratio for Atlantic salmon at normal to high temperatures. 3. Determine the maintenance dietary protein and energy requirements for Atantic salmon at normal to high temperatures. 4. Develop biochemical tools to understand the effect of temperature on the growth performance of fish. 5. Use biochemical tools to understand the effect of temperature on protein turnover and growth performance in barramundi. 6. Use biochemcial tools to understand the effect of temperature on protein turnover and growth performance in Atlantic salmon. Read moreRead less
Reasons and Rationality. The project explains how we assess the truth and falsehood of everyday claims about what people have reason to do. It also explains what legitimizes our practice of praising and blaming people for their success and failure at doing what we think they have reason to do. In so doing it provides a foundation for both our ordinary practice of holding people responsible, and for the more institutionalised counterpart of this ordinary practice in the law.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0882576
Funder
Australian Research Council
Funding Amount
$588,000.00
Summary
Polymer Characterization Facility (PCF). Future development of macromolecular and biotechnologies have the potential to revolutionize everyday life. Current applications include plastics for engineering, diagnostic devices for biochemical analysis, polymer therapeutics for drug delivery and prosthesis with specific functions. The proposed facility will provide the analytical tools required to probe and develop advanced materials with application in medicine, agriculture, composites, cosmetics, ....Polymer Characterization Facility (PCF). Future development of macromolecular and biotechnologies have the potential to revolutionize everyday life. Current applications include plastics for engineering, diagnostic devices for biochemical analysis, polymer therapeutics for drug delivery and prosthesis with specific functions. The proposed facility will provide the analytical tools required to probe and develop advanced materials with application in medicine, agriculture, composites, cosmetics, communications and electronics.Read moreRead less