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Characterisation Of The Role Of Mesenchymal Phenotypes And EGFR In Treatment-resistant Melanoma.
Funder
National Health and Medical Research Council
Funding Amount
$113,237.00
Summary
Phenotypic change has been identified in multiple settings relating to melanoma progression and metastasis. We have identified a degree of overlap between features of phenotypic plasticity, epithelial-to-mesenchymal transition, and the emergence of treatment resistance. This project will further examine mechanisms underlying these changes, focusing on the role of the epidermal growth factor.