Advanced mathematical models and methods for a randomly-varying world. This project aims to develop advanced stochastic models and novel techniques, to analytically obtain performance measures and to efficiently simulate the time evolution. This project also plans to apply new models and methods to address important problems in ecology and epidemiology. The outputs of this project will advance knowledge in mathematics as well as in the intended application areas, including ultimately in improved ....Advanced mathematical models and methods for a randomly-varying world. This project aims to develop advanced stochastic models and novel techniques, to analytically obtain performance measures and to efficiently simulate the time evolution. This project also plans to apply new models and methods to address important problems in ecology and epidemiology. The outputs of this project will advance knowledge in mathematics as well as in the intended application areas, including ultimately in improved understanding, modelling, and tracking of the spread of diseases.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE190100238
Funder
Australian Research Council
Funding Amount
$379,574.00
Summary
Chlamydial infections of birds, domesticated animals and humans. This project aims to investigate the epidemiology of an avian Chlamydia pathogen that is known to infect humans and animals, causing serious disease. Utilising molecular epidemiology approaches, this project will generate new knowledge about dynamics of where, when and how this infection spill-over occurs between different hosts. This project also aims to extend early development work on an innovative diagnostic system for detectio ....Chlamydial infections of birds, domesticated animals and humans. This project aims to investigate the epidemiology of an avian Chlamydia pathogen that is known to infect humans and animals, causing serious disease. Utilising molecular epidemiology approaches, this project will generate new knowledge about dynamics of where, when and how this infection spill-over occurs between different hosts. This project also aims to extend early development work on an innovative diagnostic system for detection of chlamydia in laboratory and point-of-care scenarios. The expected outcomes are a greatly enhanced understanding of infections in humans and animals caused by this understudied pathogen, which will allow for more effective control and management of these infections.Read moreRead less
Developing mathematical models of infection and transmission to link biology, epidemiology and public health policy. Infectious diseases constitute a significant burden on the health of the population. Understanding how best to control them requires a multi-faceted approach, combining data from biology, medicine and population health with mathematical and computational models of disease transmission. This project will investigate the "flu" and other diseases.
Discovery Early Career Researcher Award - Grant ID: DE190100805
Funder
Australian Research Council
Funding Amount
$382,656.00
Summary
Phylogenetic methods for genome surveillance of microbial pathogens. This project aims to develop phylogenetic approaches to harness the potential evolution of bacterial and virus pathogens data and to improve early detection of infectious outbreaks. Genome surveillance programs consist in routine sequencing of particular organisms to track their evolution over time. Such programs currently exist for important bacterial and virus pathogens. This project expects to develop computational methods t ....Phylogenetic methods for genome surveillance of microbial pathogens. This project aims to develop phylogenetic approaches to harness the potential evolution of bacterial and virus pathogens data and to improve early detection of infectious outbreaks. Genome surveillance programs consist in routine sequencing of particular organisms to track their evolution over time. Such programs currently exist for important bacterial and virus pathogens. This project expects to develop computational methods to improve our understanding of pathogen outbreak emergence and infectious spread using genome data. This project will expand our knowledge base and research capability in the evolution and epidemiology of infectious agents, and aid in the prevention and control strategies of infectious disease benefiting the research priorities of food and health.Read moreRead less
Nowcasting outbreaks leveraging genomic and epidemiological data. This project aims to inform outbreak response planning by developing new models of infectious disease outbreaks. The project expects to generate new knowledge on the processes driving ongoing outbreaks including those of the novel coronavirus (COVID-19) and African swine fever by integrating the latest advances in Bayesian outbreak inference alongside unique simulation approaches. Expected outcomes should include a shift in how mo ....Nowcasting outbreaks leveraging genomic and epidemiological data. This project aims to inform outbreak response planning by developing new models of infectious disease outbreaks. The project expects to generate new knowledge on the processes driving ongoing outbreaks including those of the novel coronavirus (COVID-19) and African swine fever by integrating the latest advances in Bayesian outbreak inference alongside unique simulation approaches. Expected outcomes should include a shift in how models are developed and used to inform the response to outbreaks as they unfold. This should enable more rapid outbreak containment in Australia and overseas, leading to reduced impacts on public and animal health, and associated industries.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE180101395
Funder
Australian Research Council
Funding Amount
$365,058.00
Summary
Effect of disease on reproduction plasticity and evolution in amphibians. The project aims to explore the impact of disease on reproductive success in amphibians by utilizing a holistic approach of both lab and field techniques to understand ecological mechanisms for resilience of wildlife to emerging diseases. The project will explore reproductive effort as a population persistence mechanism of declining species. This should advance knowledge of both reproductive plasticity and evolutionary ada ....Effect of disease on reproduction plasticity and evolution in amphibians. The project aims to explore the impact of disease on reproductive success in amphibians by utilizing a holistic approach of both lab and field techniques to understand ecological mechanisms for resilience of wildlife to emerging diseases. The project will explore reproductive effort as a population persistence mechanism of declining species. This should advance knowledge of both reproductive plasticity and evolutionary adaptation in the face of disease. The expected outcomes include developing targeted approaches for conservation agencies.Read moreRead less