Improving productivity: theory and application to Australian hospitals. This project aims to improve existing methods for analysing productivity and efficiency of organisations. The new methods will be applied to Australian hospitals, to analyse their productivity and efficiency, identify the best-practices and their determinants and recommend improvements and necessary reforms. The high level of healthcare costs in Australia, about 5 percent of gross domestic product, as well as their rapid and ....Improving productivity: theory and application to Australian hospitals. This project aims to improve existing methods for analysing productivity and efficiency of organisations. The new methods will be applied to Australian hospitals, to analyse their productivity and efficiency, identify the best-practices and their determinants and recommend improvements and necessary reforms. The high level of healthcare costs in Australia, about 5 percent of gross domestic product, as well as their rapid and accelerating growth, imply that application of methods developed through this project may save billions of dollars and, more importantly, thousands of lives. An expected outcome of this project will be superior theoretical and practical methods for analysing productivity and efficiency of economic systems, to enhance understanding of the potential for improvements and of the necessary reforms.Read moreRead less
Analysing and comparing concepts of addiction for improved social and health outcomes in Australia. Australia invests heavily in responding to alcohol and other drug (AOD) use. This project will analyse a key concept shaping AOD responses, namely addiction. The analysis will help develop new, more productive approaches to AOD prevention, education and treatment, contributing to improved AOD-related social and health outcomes.
Youth identity and educational change in Australia since 1950: digital archiving, re-using qualitative data and histories of the present. This is an historical and longitudinal study of Australian youth and education since the 1950s. It creates a digital archive of the study for future researchers and re-examines earlier qualitative studies to better understand generational changes in youth pathways and educational inequalities.
Building social infrastructure in settings of locational disadvantage. This project will generate improved understanding the ways in which locational disadvantage influence residents’ social networks. A national study will generate an evidence-base for understanding the extent and contours of place-based social exclusion, and inform effective policies, programs and processes targeting locational disadvantage.
Integrated Nanoplatform for Multiomics Analysis of Cell-to-Cell Interaction. This project aims to develop an integrated nanoplatform for analysis of exosomes produced by host-pathogen interaction at the single cell level. This will be accomplished by engineering an innovative device involving plasmonic nanoparticles to probe exosomes molecular profiles over time. The intended outcome is a generic and robust platform for detailed molecular analysis of the consequences of cell-to-cell interactions ....Integrated Nanoplatform for Multiomics Analysis of Cell-to-Cell Interaction. This project aims to develop an integrated nanoplatform for analysis of exosomes produced by host-pathogen interaction at the single cell level. This will be accomplished by engineering an innovative device involving plasmonic nanoparticles to probe exosomes molecular profiles over time. The intended outcome is a generic and robust platform for detailed molecular analysis of the consequences of cell-to-cell interactions. Single cell scale will greatly improve detection accuracy for heterogeneous cell populations. Benefits will include new knowledge of cell-to-cell communication and intellectual property in manufacturing, which will foster collaborations across institutions and Australian industry by providing new technological solutions.Read moreRead less
Solid-state light sources for bio-imaging and microfluidics. Solid state light sources are the light sources of the 21st century. This project will allow us to find new ways of bioimaging in living organisms applicable to diagnosing disease, and for microfluidic chip based portable instruments for on-site and point-of-care analysis in medical diagnostics, environmental monitoring, and manufacturing processes.
Mapping dynamic lipid biochemistry with high spatial and molecular detail. Lipids are a complex and underappreciated family of molecules playing important roles in all of our tissues and cells. Yet, our fundamental knowledge of lipids is limited by current technology. This project aims to develop an innovative mass spectrometry imaging platform allowing lipid biochemistry to be visualised at a level of detail not before possible. This will push boundaries in molecular imaging technology and is e ....Mapping dynamic lipid biochemistry with high spatial and molecular detail. Lipids are a complex and underappreciated family of molecules playing important roles in all of our tissues and cells. Yet, our fundamental knowledge of lipids is limited by current technology. This project aims to develop an innovative mass spectrometry imaging platform allowing lipid biochemistry to be visualised at a level of detail not before possible. This will push boundaries in molecular imaging technology and is expected to provide new fundamental knowledge about the structure, function and distributions of lipids in tissues and cells. Significant benefits should include providing new tools to unravel the functions and modifications of lipids in biology, that can be extended to many other research and industrial applications. Read moreRead less
Minimally invasive monitoring of sleep for disease management. Sleep, diet and exercise are the three pillars of wellbeing with poor sleep associated with medical issues such as obesity and congestive heart failure. This project will advance sleep analysis by researching new ways of monitoring that are highly accurate and convenient, enabling physicians to improve the monitoring of significant health issues.
Bayesian copula modelling of multivariate dependence: getting to grips with data that is far from normal. Copula models are very popular tools that are changing the way analysts deal with information rich data in fields as diverse as marketing, finance and transport studies. This project aims to improve and extend these tools, so that more accurate and reliable models can be employed, resulting in improved evidence-based decision-making.
Hybrid Imaging System for Breast Cancer Detection. Due to the ever increasing number of breast cancer mortalities in Australia, there is an urgent need for an efficient and reliable diagnostic imaging system. This research utilises a novel method to build an imaging system, which is accurate and reliable in the early detection of tumours. The work of this fellowship will improve quality of life of Australian women and put us at the international forefront of research in medical imaging, enhancin ....Hybrid Imaging System for Breast Cancer Detection. Due to the ever increasing number of breast cancer mortalities in Australia, there is an urgent need for an efficient and reliable diagnostic imaging system. This research utilises a novel method to build an imaging system, which is accurate and reliable in the early detection of tumours. The work of this fellowship will improve quality of life of Australian women and put us at the international forefront of research in medical imaging, enhancing our already significant international presence in the area. The project will potentially lead to valuable intellectual property for commercialisation opportunities besides strengthening key international collaborations.Read moreRead less