Understanding the Spatial and Social Drivers of Employment Transitions. This project reconsiders significant changes in the Australian labour market by utilising new conceptual tools based on temporal and spatial dimensions of productive activities and employment. The analysis provides an understanding of the socio-economic and spatial drivers of job and employment transitions and how they vary across Australia. The outcomes will be a new hierarchical model of labour market regions for assessin ....Understanding the Spatial and Social Drivers of Employment Transitions. This project reconsiders significant changes in the Australian labour market by utilising new conceptual tools based on temporal and spatial dimensions of productive activities and employment. The analysis provides an understanding of the socio-economic and spatial drivers of job and employment transitions and how they vary across Australia. The outcomes will be a new hierarchical model of labour market regions for assessing the social impact of employment transitions in regions, localities and remote areas providing evidence to inform region-specific policy. The innovative statistical methodology to enhance current analytical models of spatial variation in employment transitions will contribute significantly to international research. Read moreRead less
Tuneable “Nano-Shearing”: An Innovative Mechanism for the Accurate and Specific Capture of Cells and Molecules. Recent investigations have discovered a tuneable electro-hydrodynamic force which drives lateral fluid motion within a few nanometers of an electrode surface. Because the magnitude of this fluid shear force can be tuned externally (for example, via the application of an AC electric field), it provides a new capability to physically displace weakly (non-specifically) bound cellular and ....Tuneable “Nano-Shearing”: An Innovative Mechanism for the Accurate and Specific Capture of Cells and Molecules. Recent investigations have discovered a tuneable electro-hydrodynamic force which drives lateral fluid motion within a few nanometers of an electrode surface. Because the magnitude of this fluid shear force can be tuned externally (for example, via the application of an AC electric field), it provides a new capability to physically displace weakly (non-specifically) bound cellular and molecular analytes. By performing research to further understand and develop this tuneable effect, this project aims to build and test a new platform technology to enable highly efficient capture and specific detection of low concentration pathogenic molecules and circulating tumour cells (CTCs).Read moreRead less
Linked Lives: Antisocial Behaviour Across Three Generations. Antisocial behaviour involves about 10 per cent of children and/or adolescents. It has a substantial impact on many life outcomes including education, employment, family life, and offending. The costs of providing services to an antisocial child are 10 times higher than other children. Antisocial offspring are often children of antisocial parents and grandparents. The proposed project aims to assess antisocial behaviour transmitted acr ....Linked Lives: Antisocial Behaviour Across Three Generations. Antisocial behaviour involves about 10 per cent of children and/or adolescents. It has a substantial impact on many life outcomes including education, employment, family life, and offending. The costs of providing services to an antisocial child are 10 times higher than other children. Antisocial offspring are often children of antisocial parents and grandparents. The proposed project aims to assess antisocial behaviour transmitted across three generations, to document the predictors of this intergenerational transmission, and to describe how antisocial behaviour is changing over generations. This project aims to provide data to enable a more focussed delivery of services to antisocial families.Read moreRead less
Social networks and subjective wellbeing in Australia, China and the United Kingdom. Governments, industry and the community increasingly recognise that people's networks matter for health and wellbeing. For the first time this project compares developed and developing societies, Australia, China and the United Kingdom, to see how social networks affect well-being in different cultural and societal contexts.
Child & Adolescent Victimisation: Prevalence & Predictors in Australia. This is a study to determine the rate and predictors of child and adolescent experiences of victimisation in an Australian population based sample.
This study will address widespread concerns about the experiences of violence by Australian children. No previous population based studies have addressed this issue.
Expected outcomes are published papers in major journals, policy relevant data provided to Commonwealth and State ....Child & Adolescent Victimisation: Prevalence & Predictors in Australia. This is a study to determine the rate and predictors of child and adolescent experiences of victimisation in an Australian population based sample.
This study will address widespread concerns about the experiences of violence by Australian children. No previous population based studies have addressed this issue.
Expected outcomes are published papers in major journals, policy relevant data provided to Commonwealth and State governments as well as relevant NGOs.
The consequences of child and adolescent victimisation are substantial. This study will point to both the causes and prioritise strategies to reduce the level of violence experienced by children.
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A Mathematical Model of the Roles of Contraction and Oxygen in Human Wound Healing. Slow or impaired wound healing and excessive scarring associated with burns are both painful and costly. Moreover, the debilitating effect of chronic wounds can be expected to increase with the continuing aging of the population and the current rise in incidence of Type 2 diabetes. This project brings together a multidisciplinary team to develop a mathematical model of human wound healing and to drive the modelli ....A Mathematical Model of the Roles of Contraction and Oxygen in Human Wound Healing. Slow or impaired wound healing and excessive scarring associated with burns are both painful and costly. Moreover, the debilitating effect of chronic wounds can be expected to increase with the continuing aging of the population and the current rise in incidence of Type 2 diabetes. This project brings together a multidisciplinary team to develop a mathematical model of human wound healing and to drive the modelling to generate important breakthroughs at the level of basic science with implications for both experimentalists and clinicians.Read moreRead less
Non-invasive diagnosis using micropatches that sample biomarkers from skin. We are developing a technology called the micropatch that is laid onto the surface of the skin. When the patch is pulled away, it retains proteins found in the subsurface skin layers. We believe that by analysing these proteins we will be able to diagnose diseases like cancer earlier and therefore have a better chance of treating them successfully. The process is painless, and doctors already use it to give drugs and vac ....Non-invasive diagnosis using micropatches that sample biomarkers from skin. We are developing a technology called the micropatch that is laid onto the surface of the skin. When the patch is pulled away, it retains proteins found in the subsurface skin layers. We believe that by analysing these proteins we will be able to diagnose diseases like cancer earlier and therefore have a better chance of treating them successfully. The process is painless, and doctors already use it to give drugs and vaccines. In the future we hope that our technology will be simple enough for routine diagnosis, even in the Outback where doctors are hundreds of kilometres awayRead moreRead less
Multimodal biomedical imaging probes: development of advanced polymer nanocomposite devices for oncology. Despite significant research being directed toward cancer treatment, 7.6 million people died world wide in 2007. Early detection and treatment is widely recognised as being effective in significantly reducing mortality rates. Biomedical imaging techniques are routinely used for detection and staging of many cancers. However, greater sensitivity is required so that these techniques can be app ....Multimodal biomedical imaging probes: development of advanced polymer nanocomposite devices for oncology. Despite significant research being directed toward cancer treatment, 7.6 million people died world wide in 2007. Early detection and treatment is widely recognised as being effective in significantly reducing mortality rates. Biomedical imaging techniques are routinely used for detection and staging of many cancers. However, greater sensitivity is required so that these techniques can be applied to very early detection of tumours. To overcome this short-coming the next generation of imaging probes will be developed, which will require fundamental investigations in polymer and nanomaterials science to maximise imaging sensitivity and extend probe functionality. Successful outcomes will lead to significant benefits to healthcare in Australia.Read moreRead less
Classification of Microarray Gene-Expression Data. The broad aim is to provide statistical methodology for the classification of microarray gene-expression data. Microarrays are part of a new biotechnology that allows the monitoring of expression levels for thousands of genes simultaneously. The explosion in microarrays has produced massive quantities of data that require new statistical techniques for analysis in order to exploit their enormous scientific potential. One of the main uses of ....Classification of Microarray Gene-Expression Data. The broad aim is to provide statistical methodology for the classification of microarray gene-expression data. Microarrays are part of a new biotechnology that allows the monitoring of expression levels for thousands of genes simultaneously. The explosion in microarrays has produced massive quantities of data that require new statistical techniques for analysis in order to exploit their enormous scientific potential. One of the main uses of the methodology to be developed is to expedite the discovery of new subclasses of diseases. Another is to provide prediction rules for the diagnosis and treatment of diseases.Read moreRead less
Architectural design to improve Indigenous health outcomes. The project seeks to develop evidence-based knowledge on what Indigenous clients find supportive or stressful in health care settings, to formulate recommendations for architectural design and service delivery. Many Indigenous people fail to present for health care until chronically ill, due to fear or dislike of health services and their settings. This project aims to understand how design in healthcare architecture across different bu ....Architectural design to improve Indigenous health outcomes. The project seeks to develop evidence-based knowledge on what Indigenous clients find supportive or stressful in health care settings, to formulate recommendations for architectural design and service delivery. Many Indigenous people fail to present for health care until chronically ill, due to fear or dislike of health services and their settings. This project aims to understand how design in healthcare architecture across different building scales and services (clinics, hospitals, waiting rooms, wards etc) affects Indigenous people’s use and perceptions of these environments and consequent motivation to access health care services. Developing innovative and adaptable research methods, the project seeks to identify the necessary architectural design changes for health settings to facilitate access for Indigenous people.Read moreRead less