Synthetic Biology Derived Electroactive Whole Cell Microbial Biosensors. The aim of this project is to develop, using synthetic biology, electrically integrated microbial biosensors for the detection of heavy metals in the environment. Building on our existing technology, this project aims to produce novel ‘biobricks’ capable of electrically integrating electric microbes into real time environmental monitors for heavy metal contaminants. This expansion of synthetic biology, and integration of el ....Synthetic Biology Derived Electroactive Whole Cell Microbial Biosensors. The aim of this project is to develop, using synthetic biology, electrically integrated microbial biosensors for the detection of heavy metals in the environment. Building on our existing technology, this project aims to produce novel ‘biobricks’ capable of electrically integrating electric microbes into real time environmental monitors for heavy metal contaminants. This expansion of synthetic biology, and integration of electric bacteria into sensor systems, will result in a new platform technology that expands our abilities to protect the ecology, agriculture and health of terrestrial, marine and agricultural at risk areas from economic and environmental damage.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE130101401
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
A novel autotrophic biological nitrogen removal process driven by ammonia-oxidising archaea and anammox bacteria. This project will provide fundamental support to the development of more sustainable nitrogen removal processes. This would bring considerable benefits to the Australian wastewater industry and could potentially influence the way that biological nutrient removal plants are designed and operated.
E. coli as an indicator of faecal contamination in the Australian context. The goal of this research is to improve our ability to use Escherichia coli as an indicator of water quality by determining the extent to which non-faecal sources of E. coli contribute to coliform counts and to develop a method to differentiate non-faecal E. coli from those that are faecal derived.
Is mass commercialisation of silver-based nanotechnology undermining its biomedical antibacterial potential? Silver nanoparticles have demonstrated broad spectrum antibacterial potential and are increasingly used in biomedical applications to limit infection. They are also found in a growing range of everyday products such as shampoos and socks. This situation is analogous to the previous use of antibiotics for nonmedical purposes and the subsequent spread of antibiotic resistant bacteria. This ....Is mass commercialisation of silver-based nanotechnology undermining its biomedical antibacterial potential? Silver nanoparticles have demonstrated broad spectrum antibacterial potential and are increasingly used in biomedical applications to limit infection. They are also found in a growing range of everyday products such as shampoos and socks. This situation is analogous to the previous use of antibiotics for nonmedical purposes and the subsequent spread of antibiotic resistant bacteria. This project will measure silver resistance selection pressure in key microbial communities. Novel monitoring devices, a multi-technique chemistry approach, and correlative synchrotron spectroscopy and molecular biology techniques will be used to decipher the environmental silver resistome and its likely significance.Read moreRead less
Landfill Based Rapid Anaerobic Digestion of Municipal Solid Waste. The rapid digestion of municipal solid waste has the potential to make putrescible landfills obsolete. Waste can be digested prior to landfilling, eliminating odour and the emission of methane. Pre-digestion is currently performed in highly mechanised in-vessel digesters in some European locations. Demonstations in our laboratory have shown similar digestion rates can be achieved in static beds. This technology can be feasibl ....Landfill Based Rapid Anaerobic Digestion of Municipal Solid Waste. The rapid digestion of municipal solid waste has the potential to make putrescible landfills obsolete. Waste can be digested prior to landfilling, eliminating odour and the emission of methane. Pre-digestion is currently performed in highly mechanised in-vessel digesters in some European locations. Demonstations in our laboratory have shown similar digestion rates can be achieved in static beds. This technology can be feasibly scaled to digest waste streams of the size produced by Australian cities. The project will scale up this technology in a series of test cell trials at the Thiess Swanbank landfill near Ipswich, Queensland.Read moreRead less
Breaking critical barriers in soil formation of bauxite residues . Conventional methods of bauxite residue rehabilitation require expensive and unsustainable covering topsoil. Building on recent breakthroughs in eco-engineering tailings into soil, the project aims to develop a field-based technology using marine microbes and halophytic plants to accelerate in-situ soil formation from bauxite residues (incl seawater neutralised bauxite residues) under field conditions. The technology will be unde ....Breaking critical barriers in soil formation of bauxite residues . Conventional methods of bauxite residue rehabilitation require expensive and unsustainable covering topsoil. Building on recent breakthroughs in eco-engineering tailings into soil, the project aims to develop a field-based technology using marine microbes and halophytic plants to accelerate in-situ soil formation from bauxite residues (incl seawater neutralised bauxite residues) under field conditions. The technology will be underpinned by understanding the roles of marine microbe consortia and eco-engineering inputs in accelerating key mineralogical, geochemical, physical and biological changes in bauxite residues. This technology is expected to be transferable and adaptable across other alumina refineries in Australia.Read moreRead less
Eco-engineering soil from mine tailings for native plant rehabilitation. Eco-engineering soil from mine tailings for native plant rehabilitation. This project aims to develop integrated and low-cost eco-engineering technology to purposefully accelerate in-situ formation of soil from tailings for sustainable native plant community rehabilitation at metal mines. Soil shortages at mines cost the Australian mining industry billions of dollars in sustainable rehabilitation of tailings, and threaten t ....Eco-engineering soil from mine tailings for native plant rehabilitation. Eco-engineering soil from mine tailings for native plant rehabilitation. This project aims to develop integrated and low-cost eco-engineering technology to purposefully accelerate in-situ formation of soil from tailings for sustainable native plant community rehabilitation at metal mines. Soil shortages at mines cost the Australian mining industry billions of dollars in sustainable rehabilitation of tailings, and threaten the industry’s ecological and commercial sustainability. Building on recent findings of critical processes in soil formation from copper/lead–zinc tailings, this research will use key biogeochemical and rhizosphere processes in the tailing-soil to create a functional 'technosol'. This technology is intended to be used in Australian metal mines to offset the soil needed to rehabilitate tailings landforms with native plant communities.Read moreRead less
Australian Laureate Fellowships - Grant ID: FL180100036
Funder
Australian Research Council
Funding Amount
$3,011,916.00
Summary
Engineering microbes that increase coral climate resilience. This project aims to develop microbes which are able to enhance the climate resilience of corals. Coral reefs around the world are being lost at an alarming rate. Developing microbial symbionts to enhance coral climate resilience will give Australian and other coral reef ecosystems an increased chance of surviving the impact of climate change. The project will also enhance understanding of the functional roles of microbial symbionts of ....Engineering microbes that increase coral climate resilience. This project aims to develop microbes which are able to enhance the climate resilience of corals. Coral reefs around the world are being lost at an alarming rate. Developing microbial symbionts to enhance coral climate resilience will give Australian and other coral reef ecosystems an increased chance of surviving the impact of climate change. The project will also enhance understanding of the functional roles of microbial symbionts of corals, and advance the microbial symbiosis discipline globally. Expected outcomes include healthier coral reefs through the use of more climate resilient coral stock in reef conservation and restoration initiatives.Read moreRead less
Revealing the microbial process of iron-driven anaerobic ammonium oxidation. This project aims to gain fundamental understanding of the recently discovered microbially-facilitated process of anaerobic ammonium oxidation that is coupled to iron reduction. This process (called Feammox) is suggested to be responsible for significant nitrogen loss from soil and sediment ecosystems, resulting in pollution of the atmosphere and our water systems. In the project, the Feammox microorganisms will be enri ....Revealing the microbial process of iron-driven anaerobic ammonium oxidation. This project aims to gain fundamental understanding of the recently discovered microbially-facilitated process of anaerobic ammonium oxidation that is coupled to iron reduction. This process (called Feammox) is suggested to be responsible for significant nitrogen loss from soil and sediment ecosystems, resulting in pollution of the atmosphere and our water systems. In the project, the Feammox microorganisms will be enriched and characterised to reveal the metabolic details of the iron reduction and ammonium oxidation pathways. This will improve understanding of ecosystem nitrogen flux and benefit the management of nitrogen fertilizers used to meet the food and energy requirements of the world’s growing populations.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE160100615
Funder
Australian Research Council
Funding Amount
$348,200.00
Summary
Harnessing chain-forming diatoms for improved lipid biofuel production. The aim of this project is to unlock the molecular secrets of highly productive chain-forming diatom microalgae that allow them to produce high levels of biofuel lipids. The formation of multicellular chains appears key to the success of some of the most widespread and productive diatom species. Through a combination of systems biology, bioinformatics, and genetics experiments, this project aims to investigate the relationsh ....Harnessing chain-forming diatoms for improved lipid biofuel production. The aim of this project is to unlock the molecular secrets of highly productive chain-forming diatom microalgae that allow them to produce high levels of biofuel lipids. The formation of multicellular chains appears key to the success of some of the most widespread and productive diatom species. Through a combination of systems biology, bioinformatics, and genetics experiments, this project aims to investigate the relationship between chain formation and biofuel lipid productivity in Chaetoceros diatoms, and to discover genes and molecules that encode and influence these traits. The knowledge and technology generated as a result may improve biofuel yields, increase the robustness of species growing in open pond systems, and reduce processing costs such as de-watering.Read moreRead less