Formation, degradation and migration of a yet unidentified POP source. Australia has recently ratified the Stockholm Convention, targeting persistent organic pollutants (POPs) for global reduction and elimination. A significant gap exists, however, in understanding sources and pathways of POPs in Australia, and subtropical/tropical environments. Previous research has shown an extensive POP contamination in coastal Australia, and exposure of biota to elevated levels. The present study will evalua ....Formation, degradation and migration of a yet unidentified POP source. Australia has recently ratified the Stockholm Convention, targeting persistent organic pollutants (POPs) for global reduction and elimination. A significant gap exists, however, in understanding sources and pathways of POPs in Australia, and subtropical/tropical environments. Previous research has shown an extensive POP contamination in coastal Australia, and exposure of biota to elevated levels. The present study will evaluate the formation, degradation and migration of POPs, and their significance to Australia's past, present and future emissions. The outcomes will allow identification of sources, their prioritization for elimination and exposure prevention, and ultimately serve to protect the environment and human health in Australia.Read moreRead less
Atmospheric fate and processes of semi-volatile organic compounds in tropical climates. The outcomes from this study will contribute fundamental and quantitative information for evaluation of the fate of semi-volatile organic compounds (SOCs) in tropical systems, including Australia's World Heritage ecosystems such as rainforest and the Great Barrier Reef. The study addresses key international knowledge gaps with respect to the influence of climate on SOC atmospheric fate. Australia's geographic ....Atmospheric fate and processes of semi-volatile organic compounds in tropical climates. The outcomes from this study will contribute fundamental and quantitative information for evaluation of the fate of semi-volatile organic compounds (SOCs) in tropical systems, including Australia's World Heritage ecosystems such as rainforest and the Great Barrier Reef. The study addresses key international knowledge gaps with respect to the influence of climate on SOC atmospheric fate. Australia's geographical location within the tropical belt provides an ideal opportunity for leading this field of research and contributes relevant data for its commitment under the Stockholm Convention.Read moreRead less
The role of bush fires in the formation and fate of dioxin like chemicals in Australia. A global (POPs) treaty signed by more than 100 nations targets the reduction and elimination of dioxins, which are persistent, bioaccumlative and highly toxic to humans. Bushfires have been suggested as the major source of dioxins in Australia. Experimental data indicate bushfires may not represent the actual sources of dioxin. Our aim is to experimentally establish the levels of dioxins formed and re-emi ....The role of bush fires in the formation and fate of dioxin like chemicals in Australia. A global (POPs) treaty signed by more than 100 nations targets the reduction and elimination of dioxins, which are persistent, bioaccumlative and highly toxic to humans. Bushfires have been suggested as the major source of dioxins in Australia. Experimental data indicate bushfires may not represent the actual sources of dioxin. Our aim is to experimentally establish the levels of dioxins formed and re-emitted from bushfires in Australia. The results will assist to make informed decisions that lead to effective action for reducing dioxin contamination in Australia, fulfilling the treaty requirements and protecting the population and environment.
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In vitro expression and crystallization of proteins from the thermohalophile, Halothermothrix orenii. The project proposal is to develop enabling state-of-the-art protein technologies for biotechnology. We will for the first time develop a rapid and high throughput technique for the expression, purification and crystallisation of proteins from the extreme thermohalophile, Halothermothrix orenii. This important break through in protein technology will assist in determining structure and function ....In vitro expression and crystallization of proteins from the thermohalophile, Halothermothrix orenii. The project proposal is to develop enabling state-of-the-art protein technologies for biotechnology. We will for the first time develop a rapid and high throughput technique for the expression, purification and crystallisation of proteins from the extreme thermohalophile, Halothermothrix orenii. This important break through in protein technology will assist in determining structure and function relationships of thermohalophilic proteins. It is expected that such an understanding together with comparative bioinformatics will assist researchers to develop "designer proteins" with improved functions for different uses in biotechnology. It is also expected that this technology will be amenable for use with other thermohalophilic microbes.Read moreRead less
Novel Synthesis and Bio-applications of Functional Macroporous Ordered Siliceous Foams. This project will lead to advances in materials science and nanotechnology, providing high efficiency separation and purification for viruses or plasmid deoxyribonucleic acid (DNA), which are important in modern gene engineering for the treatment of genetic and acquired diseases. Application benefits also include developing a new protocol in the detection of trace amount proteins, which will afford a signific ....Novel Synthesis and Bio-applications of Functional Macroporous Ordered Siliceous Foams. This project will lead to advances in materials science and nanotechnology, providing high efficiency separation and purification for viruses or plasmid deoxyribonucleic acid (DNA), which are important in modern gene engineering for the treatment of genetic and acquired diseases. Application benefits also include developing a new protocol in the detection of trace amount proteins, which will afford a significant improvement in diverse fields such as health care. Through this project, novel macroporous materials will be fabricated using an economically and environmentally sustainable approach. These new materials will have unique structures and properties compared to conventional macroporous materials, advancing Australia's intellectual position in this discipline.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0560996
Funder
Australian Research Council
Funding Amount
$240,000.00
Summary
Oceans Law and Policy Library. This project will establish a library facility providing a comprehensive collection of international and domestic primary and secondary source materials in ocean law and policy. Materials will be both hard copy and electronic, facilitating access of materials from remote locations by partner institutions. The library will be located at the University of Wollongong, an international leader in oceans law and policy research, through the Centre for Maritime Policy. ....Oceans Law and Policy Library. This project will establish a library facility providing a comprehensive collection of international and domestic primary and secondary source materials in ocean law and policy. Materials will be both hard copy and electronic, facilitating access of materials from remote locations by partner institutions. The library will be located at the University of Wollongong, an international leader in oceans law and policy research, through the Centre for Maritime Policy. The partner universities are home to the principal centres of marine scientific research in Australia. The project will permit interdisciplinary work to be undertaken in oceans law, policy and science, allowing additional development of Australia's skill base in these fields.Read moreRead less
Frictional and viscous effects during transport in nanopores. Gas mixtures exposed to materials containing molecular sized pores (nanopores) are adsorbed, forming states of matter not existing in the bulk. Differential forces acting on the components of mixtures promote industrially and environmentally important separations. However, transport of confined fluids has been poorly understood. Recently we have made progress using computer simulation, and have proposed a highly successful theory. ....Frictional and viscous effects during transport in nanopores. Gas mixtures exposed to materials containing molecular sized pores (nanopores) are adsorbed, forming states of matter not existing in the bulk. Differential forces acting on the components of mixtures promote industrially and environmentally important separations. However, transport of confined fluids has been poorly understood. Recently we have made progress using computer simulation, and have proposed a highly successful theory. These investigations have revealed the crucial role of scattering from the surface atoms of the confining solid. Theoretical investigation of single spherical species has been initiated, and extension to other species and to mixtures is now envisaged.Read moreRead less
Inhibition of pro-inflammatory cytokine secretion- A new route to therapeutics of chronic inflammatory disease. Chronic inflammatory diseases, including rheumatoid arthritis and inflammatory bowel disease, affect millions of people leading to considerable suffering, economic loss and premature death. Anti-TNF treatments have recently shown success in the treatment of rheumatoid arthritis, inflammatory bowel disease and other conditions, however, a substantial number of patients (~50%) do not re ....Inhibition of pro-inflammatory cytokine secretion- A new route to therapeutics of chronic inflammatory disease. Chronic inflammatory diseases, including rheumatoid arthritis and inflammatory bowel disease, affect millions of people leading to considerable suffering, economic loss and premature death. Anti-TNF treatments have recently shown success in the treatment of rheumatoid arthritis, inflammatory bowel disease and other conditions, however, a substantial number of patients (~50%) do not respond to the current TNF treatments. Improved anti-TNF strategies would provide enhanced health outcomes and welcome relief to many Australians. In addition, the economic benefit of the TNF market is very substantial. Therefore the potential impact of this research is very high both for health care and economical potential.Read moreRead less
Multicomponent Transport in Nanopores. Good understanding of transport mechanisms in nanopores is crucial to the successful application of numerous recently developed novel templated microporous and mesoporous materials. This project seeks to extend a new theory developed by the applicants for single component transport in cylindrical mesopores, to cylindrical micropores as well as to multicomponent adsorbates, in conjunction with experiments using microporous and mesoporous materials such as M ....Multicomponent Transport in Nanopores. Good understanding of transport mechanisms in nanopores is crucial to the successful application of numerous recently developed novel templated microporous and mesoporous materials. This project seeks to extend a new theory developed by the applicants for single component transport in cylindrical mesopores, to cylindrical micropores as well as to multicomponent adsorbates, in conjunction with experiments using microporous and mesoporous materials such as MCM-41, VPI-5 and AlPO4-5. The outcome will be a powerful new theory for a priori prediction of transport coefficients for multicomponent fluids in nanopores based on molecular level information alone, thereby overcoming the empiricism in existing models.Read moreRead less
New multiplexed optical read-out technologies for micromachined cantilever sensor arrays. Passive sensing of chemical and biological agents is an essential capability in fields as diverse as national security, agriculture, mining and medicine. In many cases, generic sensing (e.g. are there pesticides present) as well as specific sensing (which pesticide) are both important. While sensors based on micro-electromechanical systems (MEMS) have shown extremely high performance at low cost, they have ....New multiplexed optical read-out technologies for micromachined cantilever sensor arrays. Passive sensing of chemical and biological agents is an essential capability in fields as diverse as national security, agriculture, mining and medicine. In many cases, generic sensing (e.g. are there pesticides present) as well as specific sensing (which pesticide) are both important. While sensors based on micro-electromechanical systems (MEMS) have shown extremely high performance at low cost, they have been limited to detection of a specific substance. Success in this project will make low cost generic MEMS-based sensors a reality, allowing, for the first time, wide-spread use of sensitive sensing systems in applications such as farming, container transport security, general medical practice and national security.Read moreRead less