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Synthetic Biology Derived Electroactive Whole Cell Microbial Biosensors. The aim of this project is to develop, using synthetic biology, electrically integrated microbial biosensors for the detection of heavy metals in the environment. Building on our existing technology, this project aims to produce novel ‘biobricks’ capable of electrically integrating electric microbes into real time environmental monitors for heavy metal contaminants. This expansion of synthetic biology, and integration of el ....Synthetic Biology Derived Electroactive Whole Cell Microbial Biosensors. The aim of this project is to develop, using synthetic biology, electrically integrated microbial biosensors for the detection of heavy metals in the environment. Building on our existing technology, this project aims to produce novel ‘biobricks’ capable of electrically integrating electric microbes into real time environmental monitors for heavy metal contaminants. This expansion of synthetic biology, and integration of electric bacteria into sensor systems, will result in a new platform technology that expands our abilities to protect the ecology, agriculture and health of terrestrial, marine and agricultural at risk areas from economic and environmental damage.Read moreRead less
Assessing and understanding ecological changes in highly disturbed estuaries: addressing the complexity of multiple stressors. The conservation of estuarine ecosystems is necessary due to the intrinsic value of their biodiversity and the ecosystem services they provide to humans (food, tourism, recreation). This project will identify anthropogenic stressors that pose ecological threats to estuaries. We will identify indicator species and biomarkers that are cost-effective signs of ecological cha ....Assessing and understanding ecological changes in highly disturbed estuaries: addressing the complexity of multiple stressors. The conservation of estuarine ecosystems is necessary due to the intrinsic value of their biodiversity and the ecosystem services they provide to humans (food, tourism, recreation). This project will identify anthropogenic stressors that pose ecological threats to estuaries. We will identify indicator species and biomarkers that are cost-effective signs of ecological change, useful to any manager of Australian estuaries. The simultaneous assessment of multiple stressors is a great advance in the ecological assessment of estuarine health. We will develop a manual of methods and indicators for measuring the success of environmental management programs.Read moreRead less
New tools to detect ecological effects of contaminants in estuaries. Identifying risks to estuarine environments from pollutants is difficult for environmental managers, who must choose between laboratory toxicity testing that is precise, but hard to generalise to field situations, and more realistic field-based monitoring, which is expensive, with a high signal to noise ratio. New molecular techniques may provide more options. Metabolomics can provide insights into the health of animals, and ec ....New tools to detect ecological effects of contaminants in estuaries. Identifying risks to estuarine environments from pollutants is difficult for environmental managers, who must choose between laboratory toxicity testing that is precise, but hard to generalise to field situations, and more realistic field-based monitoring, which is expensive, with a high signal to noise ratio. New molecular techniques may provide more options. Metabolomics can provide insights into the health of animals, and ecogenomics offers a way to rapidly assess the composition of an ecological community. These techniques offer great promise, but they must be cross-validated against existing methods to derive the best ’toolbox’. Working with Melbourne Water and CSIRO the investigators aim to do this using demonstration estuaries in Victoria.Read moreRead less
Oyster biomonitor for endocrine disrupting chemicals. Endocrine disrupting chemicals (EDCs) can produce alarming detrimental impacts on the reproduction and survival of aquatic species, though little is presently known in terms of their effect and impacts on sensitive marine invertebrate species. We propose the development and validation of the first marine mollusc as a biomonitor for the detection and impact assessment of estrogenic contaminants in Australian estuarine and marine waterbodies. S ....Oyster biomonitor for endocrine disrupting chemicals. Endocrine disrupting chemicals (EDCs) can produce alarming detrimental impacts on the reproduction and survival of aquatic species, though little is presently known in terms of their effect and impacts on sensitive marine invertebrate species. We propose the development and validation of the first marine mollusc as a biomonitor for the detection and impact assessment of estrogenic contaminants in Australian estuarine and marine waterbodies. Such biomonitors will provide water management agencies with the capability to manage estrogenic effluent discharges and provide the oyster industry with a tool to prevent product contamination, ensuring the continued health and sustainability of our aquatic resources.Read moreRead less
Predicting the effects of desalination plant discharge in a changing ocean environment. This project will test whether changes to the ocean environment associated with climate change (a warmer and more acidic ocean) will influence the sensitivity of marine organisms to hyper-saline discharges. Novel toxicity tests will be developed using locally relevant species that will provide crucial tools for the management of coastal habitats.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE200100043
Funder
Australian Research Council
Funding Amount
$389,000.00
Summary
Rapid Molecular (Bio)material Imaging by Infrared and Raman Microscopies. This project aims to undertake fast probe-free biochemical/chemical imaging of heterogeneity within cells and materials surfaces with new infrared and Raman imaging. It will generate new fundamental knowledge on: cell heterogeneity and dynamic processes; technologies for optimising cell printing; understanding toxicity of microplastics; and protocols for measuring materials of technological relevance. Expected outcomes inc ....Rapid Molecular (Bio)material Imaging by Infrared and Raman Microscopies. This project aims to undertake fast probe-free biochemical/chemical imaging of heterogeneity within cells and materials surfaces with new infrared and Raman imaging. It will generate new fundamental knowledge on: cell heterogeneity and dynamic processes; technologies for optimising cell printing; understanding toxicity of microplastics; and protocols for measuring materials of technological relevance. Expected outcomes include: interdisciplinary collaborations in new protocols for in-vitro drug development; cell printing technologies; environmental impacts of microplastics; and materials design. Expected benefits include innovative approaches to early stage drug design; improved environmental controls and advances in innovative materials.Read moreRead less
Developing a framework for effective oyster reef restoration. This project aims to investigate ecological barriers to the recovery of functionally extinct Sydney Rock Oyster reefs on Australia’s east coast, and restoration methods to reinstate their key ecosystem services. This project expects to create new knowledge for designing functional reefs by integrating physiology, population, community and landscape ecology. Expected outcomes are an ecological decision framework for effective oyster re ....Developing a framework for effective oyster reef restoration. This project aims to investigate ecological barriers to the recovery of functionally extinct Sydney Rock Oyster reefs on Australia’s east coast, and restoration methods to reinstate their key ecosystem services. This project expects to create new knowledge for designing functional reefs by integrating physiology, population, community and landscape ecology. Expected outcomes are an ecological decision framework for effective oyster reef restoration that can be integrated into management and policy. This project should provide significant benefits, such as the development of key strategic alliances to enhance management of estuaries, and reestablish the environmental, economic and social benefits of oyster reefs.Read moreRead less
Clothes, fibres and filters that reduce pollution by micro and nano debris. This project aims to provide scientifically verified methods to avoid, intercept and redesign products that cause the most abundant type of marine plastic pollution – clothing fibres - which has increased by over 450% in 60 years. It will determine how natural and plastic fibres, clothing brands and washing machine filters, alter fibre emissions and ecological impacts. This will enable protocols to improve products and t ....Clothes, fibres and filters that reduce pollution by micro and nano debris. This project aims to provide scientifically verified methods to avoid, intercept and redesign products that cause the most abundant type of marine plastic pollution – clothing fibres - which has increased by over 450% in 60 years. It will determine how natural and plastic fibres, clothing brands and washing machine filters, alter fibre emissions and ecological impacts. This will enable protocols to improve products and the environment, and reduce health risks that will benefit the public, government regulation and companies in designing "eco-friendly" products.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE180100121
Funder
Australian Research Council
Funding Amount
$384,671.00
Summary
Genomic library infrastructure for ancient environmental samples. This project aims to enable automated genome recovery from diverse environmental samples, without contamination risk. For more than 100 years, environmental scientists have studied diverse organism / environment interactions using a variety of conceptual and technical tools. Recently, studies of ancient and historical DNA have come to complement these tools and to occupy a significant place in environmental studies conducted over ....Genomic library infrastructure for ancient environmental samples. This project aims to enable automated genome recovery from diverse environmental samples, without contamination risk. For more than 100 years, environmental scientists have studied diverse organism / environment interactions using a variety of conceptual and technical tools. Recently, studies of ancient and historical DNA have come to complement these tools and to occupy a significant place in environmental studies conducted over serial time. The project’s addition to the existing dual Ancient DNA complex facility at Griffith University will comprise two liquid handling workstations, each being housed in separate, self-contained, ancient DNA laboratories. The new facility will enable many researchers to have unprecedented access to an ancient DNA facility and a high level of technical support.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0668039
Funder
Australian Research Council
Funding Amount
$160,000.00
Summary
Sydney Harbour Institute of Marine Science (SHIMS) aquarium facility. With the global proportion of people living in cities now exceeding 50%, the Sydney Harbour Institute of Marine Science will champion the area of urban marine science. The proposed aquarium facility will support multidisciplinary research to find solutions for the environmental problems of marine habitats in urban areas. Research at SHIMS will examine how coastal environments are affected by human impacts, recreational fisheri ....Sydney Harbour Institute of Marine Science (SHIMS) aquarium facility. With the global proportion of people living in cities now exceeding 50%, the Sydney Harbour Institute of Marine Science will champion the area of urban marine science. The proposed aquarium facility will support multidisciplinary research to find solutions for the environmental problems of marine habitats in urban areas. Research at SHIMS will examine how coastal environments are affected by human impacts, recreational fisheries, invasive pests; develop novel technologies for detection of environmental and climate change; and provide management options to protect ports and harbours from threatening processes. The location in such a commercially and recreationally busy harbour provides excellent opportunities for research and education.Read moreRead less