Synthetic Biology Derived Electroactive Whole Cell Microbial Biosensors. The aim of this project is to develop, using synthetic biology, electrically integrated microbial biosensors for the detection of heavy metals in the environment. Building on our existing technology, this project aims to produce novel ‘biobricks’ capable of electrically integrating electric microbes into real time environmental monitors for heavy metal contaminants. This expansion of synthetic biology, and integration of el ....Synthetic Biology Derived Electroactive Whole Cell Microbial Biosensors. The aim of this project is to develop, using synthetic biology, electrically integrated microbial biosensors for the detection of heavy metals in the environment. Building on our existing technology, this project aims to produce novel ‘biobricks’ capable of electrically integrating electric microbes into real time environmental monitors for heavy metal contaminants. This expansion of synthetic biology, and integration of electric bacteria into sensor systems, will result in a new platform technology that expands our abilities to protect the ecology, agriculture and health of terrestrial, marine and agricultural at risk areas from economic and environmental damage.Read moreRead less
In-situ electrochemical generation of caustic and oxygen from sewage for emission control in sewers. This project aims to deliver an innovative technology that controls the emission of notorious compounds from sewer networks using chemicals directly produced from sewage, with electricity being the input. Compared to existing methods, this technology provides a much safer and more environmentally friendly solution, at less than 50 per cent of the cost.
Australian Laureate Fellowships - Grant ID: FL180100036
Funder
Australian Research Council
Funding Amount
$3,011,916.00
Summary
Engineering microbes that increase coral climate resilience. This project aims to develop microbes which are able to enhance the climate resilience of corals. Coral reefs around the world are being lost at an alarming rate. Developing microbial symbionts to enhance coral climate resilience will give Australian and other coral reef ecosystems an increased chance of surviving the impact of climate change. The project will also enhance understanding of the functional roles of microbial symbionts of ....Engineering microbes that increase coral climate resilience. This project aims to develop microbes which are able to enhance the climate resilience of corals. Coral reefs around the world are being lost at an alarming rate. Developing microbial symbionts to enhance coral climate resilience will give Australian and other coral reef ecosystems an increased chance of surviving the impact of climate change. The project will also enhance understanding of the functional roles of microbial symbionts of corals, and advance the microbial symbiosis discipline globally. Expected outcomes include healthier coral reefs through the use of more climate resilient coral stock in reef conservation and restoration initiatives.Read moreRead less
New drugs against parasitic nematodes of livestock animals. New drugs against parasitic nematodes of livestock animals. This project aims to develop an innovative technology platform to deliver novel anti-infectives as biotechnological outcomes, using postgenomics, computing and chemistry. Advanced molecular, computer and chemistry technologies provide unprecedented opportunities to design radically new interventions against socioeconomically important infectious diseases affecting billions of a ....New drugs against parasitic nematodes of livestock animals. New drugs against parasitic nematodes of livestock animals. This project aims to develop an innovative technology platform to deliver novel anti-infectives as biotechnological outcomes, using postgenomics, computing and chemistry. Advanced molecular, computer and chemistry technologies provide unprecedented opportunities to design radically new interventions against socioeconomically important infectious diseases affecting billions of animals worldwide. Anticipated outcomes are the design of radically new chemotherapies to control parasitic diseases, the translation of fundamental research into biotechnological outcomes, international visibility of Australian science, and a solid skills- and knowledge-base in veterinary drug development.Read moreRead less
Exploiting bacterial metal resistance machinery for metal ion nano-biosensors development. This project aims to integrate advanced materials chemistry, molecular biology, bio-electrochemical and synchrotron imaging approaches to understand the role of silver resistance machinery of bacteria in their ability to form silver nanoparticles. This aims to enable discovery of new metal-specific reductase enzymes. The fundamental biomolecular understanding of bacterial silver resistance will allow the u ....Exploiting bacterial metal resistance machinery for metal ion nano-biosensors development. This project aims to integrate advanced materials chemistry, molecular biology, bio-electrochemical and synchrotron imaging approaches to understand the role of silver resistance machinery of bacteria in their ability to form silver nanoparticles. This aims to enable discovery of new metal-specific reductase enzymes. The fundamental biomolecular understanding of bacterial silver resistance will allow the use of a silver-binding protein to develop a series of next-generation nano-biosensors. These biosensing platforms will provide high-throughput, cost-effective, selective, sensitive and continuous monitoring of heavy metal ions in effluents from mining and mineral processing industries in a real-time fashion.Read moreRead less
Biosynthesis of multiple-nonmetal codoped titania nanoparticles for visible light photocatalysis. Nano-photocatalysts' are particles of very small size that can degrade organic wastes and harmful microorganisms, when exposed to light. Titania is the most commonly used photocatalyst, but the limitation with existing titania is that it is mainly active in ultraviolet (UV) light. UV-light cannot be used for indoor applications because UV is mutagenic and causes cancer. This project will use an eco- ....Biosynthesis of multiple-nonmetal codoped titania nanoparticles for visible light photocatalysis. Nano-photocatalysts' are particles of very small size that can degrade organic wastes and harmful microorganisms, when exposed to light. Titania is the most commonly used photocatalyst, but the limitation with existing titania is that it is mainly active in ultraviolet (UV) light. UV-light cannot be used for indoor applications because UV is mutagenic and causes cancer. This project will use an eco-friendly approach to develop novel titania nanoparticles, which will be active in visible light. Success will lead to new options in the management of our organic wastes and wastewaters (global problems), plant disease control, clean clinical surroundings, and add value to our day-to-day products like self-cleaning windows, and textiles.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE220101471
Funder
Australian Research Council
Funding Amount
$441,100.00
Summary
Controlling uranium species to its long-term stability in bioremediation. This project aims to reveal the mechanisms of uranium transformation and immobilisation in both aerobic and anaerobic conditions of bioremediation with the emphasis on elucidating stable uranium immobilised under different pathways and conditions. This project expects to generate new knowledge regarding the relationship between uranium speciation and stability with the matrix mineral, microbiota, and environmental conditio ....Controlling uranium species to its long-term stability in bioremediation. This project aims to reveal the mechanisms of uranium transformation and immobilisation in both aerobic and anaerobic conditions of bioremediation with the emphasis on elucidating stable uranium immobilised under different pathways and conditions. This project expects to generate new knowledge regarding the relationship between uranium speciation and stability with the matrix mineral, microbiota, and environmental conditions. Expected outcomes from this project include new strategies for preferential immobilisation of uranium to stable species that are resistant to air and acid. The anticipated benefits of this project include mitigating uranium contamination and promoting the sustainable development of the uranium industry in Australia.Read moreRead less
Simultaneous dissolved methane and nitrogen removal. Direct anaerobic treatment of wastewater converts majority of organic matters in wastewater to methane, an energy source. However, up to 50% of the methane produced stays dissolved in wastewater. Its subsequent stripping to atmosphere in aerobic treatment not only causes significant loss of energy but also emission of a potent greenhouse gas. This project aims to develop a technology that not only avoids methane stripping but also enables its ....Simultaneous dissolved methane and nitrogen removal. Direct anaerobic treatment of wastewater converts majority of organic matters in wastewater to methane, an energy source. However, up to 50% of the methane produced stays dissolved in wastewater. Its subsequent stripping to atmosphere in aerobic treatment not only causes significant loss of energy but also emission of a potent greenhouse gas. This project aims to develop a technology that not only avoids methane stripping but also enables its beneficial use to enhance nitrogen removal, which is otherwise typically unsatisfactory due to the lack of organic carbon to support denitrification. The project will provide strong support to the Australian water industry in their endeavour to achieve energy- and carbon-neutral wastewater services.Read moreRead less
Combining recycled water use, biofuel production and phytoremediation of contaminated land and biosolids. The storage of biosolids, by-products of sewage treatment, is an environmentally unsustainable practice exacerbated by the presence of inorganic and organic contaminants. Phytoremediation is a plant-based technology which is potentially a cost-effective option for progressive long-term and sustainable clean-up of contaminated soils and sediments. Combining metal extraction by plants with r ....Combining recycled water use, biofuel production and phytoremediation of contaminated land and biosolids. The storage of biosolids, by-products of sewage treatment, is an environmentally unsustainable practice exacerbated by the presence of inorganic and organic contaminants. Phytoremediation is a plant-based technology which is potentially a cost-effective option for progressive long-term and sustainable clean-up of contaminated soils and sediments. Combining metal extraction by plants with reuse of wastewater and the production of a biofuel will provide multiple benefits of a cleaner environment, water conservation, waste reduction, carbon capture and a reduction in fossil fuel use. Development of such a low-cost combined bioenergy/remediation system will be of considerable local/regional benefit and national significance.Read moreRead less