Understanding Gene-environment Interactions In Relation To Risk Of Age-related Cataract
Funder
National Health and Medical Research Council
Funding Amount
$86,514.00
Summary
Age-related cataract is the clouding of the lens, a leading cause of visual impairment among older persons. The burden of this common eye disease will only increase as the population ages. Besides age, other environmental and genetic risk factors that increase the risk of cataract have been identified. The aim of this research is to examine how the interplay of genes and environment contributes to age-related cataract formation, using population-based data of established studies.
Genetic And Environmental Risk Factors On Lifetime Risk Of Obstructive Lung Disease
Funder
National Health and Medical Research Council
Funding Amount
$351,414.00
Summary
Classification of lifetime phenotypes of obstructive lung disease allows investigation of the effect of environmental and genetic influences on specific phenotypes along with the interactions between them. Through improved phenotyping ,the currently inconsistent relationships between asthma and COPD and their associations with genetic and environmental factors may become clearer.
Using Law To Improve Population Health and the Quality of Health Care Services. There are huge gaps in our understanding of how legal rules and processes impact population health and the quality of health care services in Australia. This research program will begin to fill those gaps by addressing topical issues such as medical negligence litigation, the coroner's role in injury prevention, and the use of medical science in the courtroom. The findings will be useful to government policymakers, ....Using Law To Improve Population Health and the Quality of Health Care Services. There are huge gaps in our understanding of how legal rules and processes impact population health and the quality of health care services in Australia. This research program will begin to fill those gaps by addressing topical issues such as medical negligence litigation, the coroner's role in injury prevention, and the use of medical science in the courtroom. The findings will be useful to government policymakers, regulators, and judges, as well as professionals working in both the legal and health care fields. But most importantly, the findings will serve patients by helping to shape strategies and reforms that enable Australia's health care system to deliver services that are safer, of higher quality, fairer, and more efficient.Read moreRead less
Unequal futures: A critical investigation of regional and sociocultural variations in teenage pregnancy. The overarching aim of this project is to investigate geographical and sociocultural variations in teenage pregnancy in Australia, encompassing the over-representation of young Indigenous teenage mothers. It considers the implications of these differences for government policy.
The project aims to:
- define the parameters of teenage pregnancy
- map the complex social context in whic ....Unequal futures: A critical investigation of regional and sociocultural variations in teenage pregnancy. The overarching aim of this project is to investigate geographical and sociocultural variations in teenage pregnancy in Australia, encompassing the over-representation of young Indigenous teenage mothers. It considers the implications of these differences for government policy.
The project aims to:
- define the parameters of teenage pregnancy
- map the complex social context in which to understand teenage pregnancy
- identify the information, support, and services most likely to ensure that young women have options for pregnancy and motherhood which maximise their health and wellbeing
- identify factors which account for unintentional teenage pregnancy and strategies for prevention or amelioration.
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An Investigation Of The Role Of Gene-environment Interactions And Epigenetics In Depression: Nature Combined With Nurture.
Funder
National Health and Medical Research Council
Funding Amount
$337,602.00
Summary
Depression is one of the biggest public health problems, yet the causes remain largely unknown. This study aims to determine how environmental factors can combine with particular genes to increases an individual’s risk of depression. Environmental factors can also cause modifications to genes which can affect an individual’s health. This study will thus also examine whether women with post-natal depression and their children have different gene modifications than those without depression.
LIFEPATH: Life-course Biological Pathways Underlying Social Differences In Healthy Ageing
Funder
National Health and Medical Research Council
Funding Amount
$470,466.00
Summary
Healthy ageing varies across society due to environmental, behavioural and social circumstances that affect peoples’ lives. To improve our ability to change this we will investigate suspected biological mechanisms over the life course. Using repeated blood samples collected during a large prospective study, we will measure a very large number of biological markers and analyse these combined with lifestyle and behavioural information to identify the modifiable predictors of healthy ageing.
Informing Vaccination Strategies For Pregnant Women Through Linked Population Health Data
Funder
National Health and Medical Research Council
Funding Amount
$318,768.00
Summary
Vaccination during pregnancy has health benefits for mothers and their infants; however, it is a relatively new area of research, and the immediate and long-term consequences for children are currently not well understood. As part of this fellowship, I plan to conduct research into the long-term health impacts of vaccination during pregnancy. This fellowship will build my career as a perinatal epidemiologist and establish expertise in Australia related to vaccines given during pregnancy.
Consistency and continuity in childhood adversity: the nature and history of multiple disadvantage in families with young children. This project has both theoretical and practical value and it falls within the National Research Priority Goal of 'A healthy start to life'. It will improve our understanding of how adversity influences children's development and long-term outcomes by focussing on multiple family disadvantage rather than individual adversities. It will help policy development and s ....Consistency and continuity in childhood adversity: the nature and history of multiple disadvantage in families with young children. This project has both theoretical and practical value and it falls within the National Research Priority Goal of 'A healthy start to life'. It will improve our understanding of how adversity influences children's development and long-term outcomes by focussing on multiple family disadvantage rather than individual adversities. It will help policy development and service delivery by identifying the extent to which families that experience one form of adversity are also likely to experience other types of adversity, either at the same time or in the future. At present, many policies and services are aimed at specific adversities and may not meet the needs of families experiencing multiple disadvantage.Read moreRead less