Engineering heart tissue by manipulating the physical and cellular culture environment in bioreactors. This work using cell culture systems to generate heart tissue outside of the body contributes to the development of advanced technologies in cardiac tissue engineering. The knowledge obtained will lead to new medical applications in heart repair and reconstruction to enhance human health and well being.
Adding a health dimension to integrated automation solutions for intelligent homes. We present a vision for the implementation of intelligent health care technology in the home of the future, focusing on areas of research that have the highest potential payoff over the next ten years for the community, the government and our industry partners. By "intelligent health care technology" we mean smart devices and systems that are aware of their context and can therefore assimilate information to supp ....Adding a health dimension to integrated automation solutions for intelligent homes. We present a vision for the implementation of intelligent health care technology in the home of the future, focusing on areas of research that have the highest potential payoff over the next ten years for the community, the government and our industry partners. By "intelligent health care technology" we mean smart devices and systems that are aware of their context and can therefore assimilate information to support care decisions. We aim to integrate these systems into existing home automation systems designed and marketed by our industrial collaborators. Outcomes will be underpinned by new knowledge acquisition and knowledge based decision systems.Read moreRead less
Design Optimisation for Fabrication of Ceramic Prosthetic Devices. The project aims to develop computer aided design and fabrication for ceramic prosthesis. It will help establish a world-class biomedical instrumentation company having part of its research and development in Australia. The study will not only foster domestic research expertise, but also provide the local prosthetic community and biomedical industry with an opportunity to participate in further innovation of biomaterials, biomedi ....Design Optimisation for Fabrication of Ceramic Prosthetic Devices. The project aims to develop computer aided design and fabrication for ceramic prosthesis. It will help establish a world-class biomedical instrumentation company having part of its research and development in Australia. The study will not only foster domestic research expertise, but also provide the local prosthetic community and biomedical industry with an opportunity to participate in further innovation of biomaterials, biomedical software and equipment. The outcomes will directly benefit the Australian prosthetic profession. Improvement in prosthesis restorative longevity for our increasing ageing population will support the national research goal of ageing well, ageing productively.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0989384
Funder
Australian Research Council
Funding Amount
$233,000.00
Summary
High-speed, three-dimensional, x-ray fluoroscopy for accurate measurement of human joint motion. This proposal addresses one of the most difficult and long-standing problems in the field of biomechanics: How can human joint motion be measured accurately and non-invasively during common activities such as walking, stair ambulation and running? Low-dose, high-speed, three-dimensional, x-ray fluoroscopy provides an excellent solution to this problem and, in so doing, can play a pivotal role in heal ....High-speed, three-dimensional, x-ray fluoroscopy for accurate measurement of human joint motion. This proposal addresses one of the most difficult and long-standing problems in the field of biomechanics: How can human joint motion be measured accurately and non-invasively during common activities such as walking, stair ambulation and running? Low-dose, high-speed, three-dimensional, x-ray fluoroscopy provides an excellent solution to this problem and, in so doing, can play a pivotal role in healthcare, through clinical gait analysis and gait rehabilitation (diagnosis, prevention and treatment of movement disorders); in sports, through the development of personalized training programs for elite athletes; and in entertainment, through the creation of physics-based animations for the video/digital games industry.Read moreRead less
Predictive models to study neuromuscular control of walking in older people. This project aims to address a major challenge in human motion simulation: to deliver computationally-efficient predictive simulations of movement biomechanics. It plans to bring together the latest developments in computational modelling, medical imaging and nonlinear optimal control theory to advance current understanding of how individual lower-limb muscles stabilise and control body movement during locomotion in hea ....Predictive models to study neuromuscular control of walking in older people. This project aims to address a major challenge in human motion simulation: to deliver computationally-efficient predictive simulations of movement biomechanics. It plans to bring together the latest developments in computational modelling, medical imaging and nonlinear optimal control theory to advance current understanding of how individual lower-limb muscles stabilise and control body movement during locomotion in healthy young and older adults. New knowledge of how age-related changes in muscle mechanical properties affect the neuromuscular control of walking may assist in the design of more targeted exercise-based therapies aimed at maintaining independent function and improving the quality of life for older adults.Read moreRead less
Optimised distributed stimulation of muscle. The project aims to extend to humans, a method of producing a non-fatiguing, smooth, submaximal muscle contraction. The method using multiple electrodes, stimulated at different times, with those times being adjusted for optimum smoothness at low stimulation rates. This will enable the gathering of information about the mechanics of muscle undergoing near physiological contractions, which will be of interest to researchers in Biomechanics. It will ....Optimised distributed stimulation of muscle. The project aims to extend to humans, a method of producing a non-fatiguing, smooth, submaximal muscle contraction. The method using multiple electrodes, stimulated at different times, with those times being adjusted for optimum smoothness at low stimulation rates. This will enable the gathering of information about the mechanics of muscle undergoing near physiological contractions, which will be of interest to researchers in Biomechanics. It will also be a step towards the restoration of function to spinal cord injured patients.Read moreRead less
Silk Fibroin Optofluidic Chips. Unlike any other material, even any other biologically occurring material, silk is unique in being very transparent, able to be shaped on a very small scale and can keep natural chemicals like proteins and enzymes active. This project will use silk to make optical devices and sensors. Optics made from silk will have all these properties, which means that they can be used as sensors and devices in biochemistry applications that have never been possible before. Thes ....Silk Fibroin Optofluidic Chips. Unlike any other material, even any other biologically occurring material, silk is unique in being very transparent, able to be shaped on a very small scale and can keep natural chemicals like proteins and enzymes active. This project will use silk to make optical devices and sensors. Optics made from silk will have all these properties, which means that they can be used as sensors and devices in biochemistry applications that have never been possible before. These cost-effective devices will have the potential to enhance healthcare, emergency medicine and assist early medical diagnosis.Read moreRead less
Hybrid Sensor-based Physiological Control of an Implantable Rotary Blood Pump. With over 11 million people needing heart transplants worldwide and only 3000 donor hearts, an effective alternative therapy is needed. The Ventracor Ltd. rotary blood pump is one possible approach whereby a fully implantable mechanical device assists the failing heart. The innovative steps in this research proposal will be a means to robustly and safely control the speed of the pump to meet the metabolic needs of the ....Hybrid Sensor-based Physiological Control of an Implantable Rotary Blood Pump. With over 11 million people needing heart transplants worldwide and only 3000 donor hearts, an effective alternative therapy is needed. The Ventracor Ltd. rotary blood pump is one possible approach whereby a fully implantable mechanical device assists the failing heart. The innovative steps in this research proposal will be a means to robustly and safely control the speed of the pump to meet the metabolic needs of the body. Apart from the obvious health benefits for patients, this will provide the company with a huge market advantage that will also help to bolster the Australian medical device industry.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0453623
Funder
Australian Research Council
Funding Amount
$164,640.00
Summary
Peripheral quantitative computed tomography facility for analysing bone material and structural properties. We aim to establish a facility that allows non-invasive measurement of apparent material and structural properties of small animal and human bone using leading-edge technology, peripheral quantitative computed tomography (pQCT). pQCT measurements, incorporated into our fundamental bone research will improve our understanding of the role of mechanical, environmental and local factors in re ....Peripheral quantitative computed tomography facility for analysing bone material and structural properties. We aim to establish a facility that allows non-invasive measurement of apparent material and structural properties of small animal and human bone using leading-edge technology, peripheral quantitative computed tomography (pQCT). pQCT measurements, incorporated into our fundamental bone research will improve our understanding of the role of mechanical, environmental and local factors in regulating bone and mineral metabolism and altering bone properties. This has implications for maximising bone strength and promoting optimal health throughout life. The facility will be used for a diverse range of multidisciplinary basic bone research and is vital in order to maintain international competitiveness in the field.Read moreRead less
Automated texture selection and classification methods for detection of osteoarthritis in knee radiographs. In Australia there are 1-2 million OA sufferers, a condition that costs approximately $9 billion annually. This project will address an important problem of early detection and monitoring of OA and this remains in line with the National Research Priority 2. Potential outcomes of the project will result in better diagnosis and treatment of OA, reduced discomfort to the individual and saving ....Automated texture selection and classification methods for detection of osteoarthritis in knee radiographs. In Australia there are 1-2 million OA sufferers, a condition that costs approximately $9 billion annually. This project will address an important problem of early detection and monitoring of OA and this remains in line with the National Research Priority 2. Potential outcomes of the project will result in better diagnosis and treatment of OA, reduced discomfort to the individual and saving to the national economy. This project will improve existing activity and rehabilitation programs such as exercise of lower limbs and it will help in developing diets for healthy people and OA sufferers.Read moreRead less