Bioanalytical Microchips Based on Integrated, Application Tailored Monolithic Modules. Microfluidic devices offer substantial advantages over current technology, in terms of speed, cost of analysis, portability, operator simplicity and safety. Integrating multiple analytical processes within a simple and reliable portable device will lead to application in a range of areas, from pharmacology to therapeutic drug monitoring, proteomic and metabolomic screening for disease diagnosis and drug develo ....Bioanalytical Microchips Based on Integrated, Application Tailored Monolithic Modules. Microfluidic devices offer substantial advantages over current technology, in terms of speed, cost of analysis, portability, operator simplicity and safety. Integrating multiple analytical processes within a simple and reliable portable device will lead to application in a range of areas, from pharmacology to therapeutic drug monitoring, proteomic and metabolomic screening for disease diagnosis and drug development, and also for performing clinical diagnostics in a rural area. This will significantly impact on the quality of life of the Nation as a whole, not only due to expedient diagnosis and treatment which has obvious health benefits, but also in the considerable financial benefits that result from early and efficient treatment. Read moreRead less
Performance and design optimisation of oscillating water column ocean wave energy converters. This project will develop an optimised design for ocean wave energy extraction devices, known as oscillating water columns. This will significantly reduce energy conversion losses from oscillating water columns and contribute towards making them internationally competitive with other renewable energy technologies.
Predictive cost and maintenance models for bidding and short term scheduling strategies in hydro power plants. The aim of this project is to develop knowledge based models that can be used to estimate the costs implicit in operating hydro-electric power generation systems in intermittent and off-design modes. These costs manifest in increased maintenance, loss of water supply and opportunity costs or values. A model of the Tasmanian system would be unique, and the application of knowledge based ....Predictive cost and maintenance models for bidding and short term scheduling strategies in hydro power plants. The aim of this project is to develop knowledge based models that can be used to estimate the costs implicit in operating hydro-electric power generation systems in intermittent and off-design modes. These costs manifest in increased maintenance, loss of water supply and opportunity costs or values. A model of the Tasmanian system would be unique, and the application of knowledge based systems to cost and decision making in this situation is novel. Opportunities exist to collaborate with Norwegian researchers. The success of the project will lead to better utilization of the Tasmanian renewable energy resource.Read moreRead less
Optimisation of Road Network Maintenance Strategies for Life-Cycle Costs. The future of Tasmania and the nation as a competitive force in the international market is intimately linked to its transportation infrastructure network. The successful maintenance and performance of the road component is essential for an efficient and integrated system and minimisation of freight costs. The research proposes to develop a less empirical and phenomenological method of predicting the future performance of ....Optimisation of Road Network Maintenance Strategies for Life-Cycle Costs. The future of Tasmania and the nation as a competitive force in the international market is intimately linked to its transportation infrastructure network. The successful maintenance and performance of the road component is essential for an efficient and integrated system and minimisation of freight costs. The research proposes to develop a less empirical and phenomenological method of predicting the future performance of pavements, based on optimisation of maintenance strategies, by incorporating the use of probabilistic methods and Geographical Information Systems (GIS) into new Whole of Life Costing (WOLC) models.Read moreRead less
Island Perspective: A critical examination into Tasmania's internationally recognised regional identity through the contribution of its contemporary studio furniture, 1970-2003. Contemporary studio furniture in Tasmania has a leading national reputation, and international recognition. This project will investigate the practice of the best of contemporary Tasmanian studio furniture to interpret its social and economic history as a reflection on an island culture. The outcomes will be a consolida ....Island Perspective: A critical examination into Tasmania's internationally recognised regional identity through the contribution of its contemporary studio furniture, 1970-2003. Contemporary studio furniture in Tasmania has a leading national reputation, and international recognition. This project will investigate the practice of the best of contemporary Tasmanian studio furniture to interpret its social and economic history as a reflection on an island culture. The outcomes will be a consolidated body of unique, hitherto undocumented knowledge from the 1970s to the present, which explores identity and place throught the diversity of individual design philosophy and furniture production. The significance of this knowledge will be its contributuon towards a dialogue between political, cultural and environmental positions on an island identity within a global context.Read moreRead less
Managing Fresh-Water Resources in Saline Environments. Australian industry and urban developments often rely on a secure supply of fresh water. In many situations, the fresh water occurs adjacent to large expanses of saline water. This poses special constraints on how the fresh water can be recovered. This project undertakes careful mathematical modelling of fresh water recovery from reservoirs and from within islands (where it may be the only practical source of drinking water). The injecti ....Managing Fresh-Water Resources in Saline Environments. Australian industry and urban developments often rely on a secure supply of fresh water. In many situations, the fresh water occurs adjacent to large expanses of saline water. This poses special constraints on how the fresh water can be recovered. This project undertakes careful mathematical modelling of fresh water recovery from reservoirs and from within islands (where it may be the only practical source of drinking water). The injection and extraction of ground water in novel "mineral leaching" mining technology will also be investigated.Read moreRead less
A longitudinal study of neuropsychological and neuromotor effects of low level manganese exposure. This study will investigate the neuropsychological and neuromotor effects of low level exposure to mangenese particulate. Previous studies have indicated symptomology of high level exposure, but there is contention in the literature regarding the effects of low levels of exposure. Our aim is to refine measures of cumulative exposure and develop a more comprehensive and senstitive testing protocol t ....A longitudinal study of neuropsychological and neuromotor effects of low level manganese exposure. This study will investigate the neuropsychological and neuromotor effects of low level exposure to mangenese particulate. Previous studies have indicated symptomology of high level exposure, but there is contention in the literature regarding the effects of low levels of exposure. Our aim is to refine measures of cumulative exposure and develop a more comprehensive and senstitive testing protocol than has been reported thus far. These measures and protocols will be incorporated into a longitudinal design, which has not been conducted in research studies to date. In addition, a database of exposure variables will be developed to facilitate long-term, accurate research into the effects of the low levels of exposure.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE150100094
Funder
Australian Research Council
Funding Amount
$400,000.00
Summary
Development of a world-class facility for three dimensional dynamic testing. Development of a world-class facility for three dimensional dynamic testing: This project aims to establish a world-class facility for multi-directional dynamic testing. Currently there are no such facilities in Australia. The ability to recreate dynamic motion in all available degrees-of-freedom opens up enormous fields of research not currently possible in Australia. This includes such areas as vibration testing, mate ....Development of a world-class facility for three dimensional dynamic testing. Development of a world-class facility for three dimensional dynamic testing: This project aims to establish a world-class facility for multi-directional dynamic testing. Currently there are no such facilities in Australia. The ability to recreate dynamic motion in all available degrees-of-freedom opens up enormous fields of research not currently possible in Australia. This includes such areas as vibration testing, materials testing, biomechanics and human factors, blast and earthquake simulations, field robotics, automotive safety research, flight/vehicle simulation, and marine applications including sloshing of liquids and liquefaction of fines. In conjunction with a 3D laser doppler system this facility will be unique in the world for dynamic mechanical testing.Read moreRead less
Freshwater biofouling of hydraulic conduits: impact, mitigation, and control, and the consequences of Climate Change. National economic and environmental benefits will flow from increased outputs of renewable energy from hydroelectric power systems. Improved performance of canals and pipelines will enable energy and water losses to be reduced and will provide the National Electricity Market with additional renewable energy, lowering the requirement for fossil fuels. Knowledge of the impacts of ....Freshwater biofouling of hydraulic conduits: impact, mitigation, and control, and the consequences of Climate Change. National economic and environmental benefits will flow from increased outputs of renewable energy from hydroelectric power systems. Improved performance of canals and pipelines will enable energy and water losses to be reduced and will provide the National Electricity Market with additional renewable energy, lowering the requirement for fossil fuels. Knowledge of the impacts of Climate Change will enable industry to manage changes in rainfall pattern and conduit biofouling. An improved understanding of biofilms can be applied to achieve wider national benefit in water reticulation, irrigation systems and maritime applications. The team will develop research skills and technical expertise and train PhD students and industry counterparts.Read moreRead less
Development of an implantable blood flow and pressure monitor for pulmonary hypertension. The aim is to develop an implantable device for continuous measurement of blood pressure and flow rate in the pulmonary artery. The device is to store data and download it on request to an external device. Development steps include design of the sensor lead incorporating impedance electrodes and a pressure transducer, numerical modelling of the electrode system, characterising pressure and flow waveforms f ....Development of an implantable blood flow and pressure monitor for pulmonary hypertension. The aim is to develop an implantable device for continuous measurement of blood pressure and flow rate in the pulmonary artery. The device is to store data and download it on request to an external device. Development steps include design of the sensor lead incorporating impedance electrodes and a pressure transducer, numerical modelling of the electrode system, characterising pressure and flow waveforms for condensed storage, establishing flow sensor and blood flow relationships and assessment of sensor stability and calibration demands. The device will facilitate research in pulmonary hypertension and may lead to clinical devices for monitoring effectiveness of treatment.Read moreRead less