Understanding The Link Between Mitochondrial Biogenesis And Disease
Funder
National Health and Medical Research Council
Funding Amount
$421,055.00
Summary
As the predominate energy producers of our cells, mitochondria are implicated in a variety of diseases. To function properly, these dynamic organelles rely on protein components that regulate their structure and distribution throughout the cell. My work aims to expand our knowledge of the way these components control mitochondrial shape and trafficking. By understanding the correlation between mitochondrial morphology and function, we will gain insight into related diseases.
This research will elucidate pathways in the brain that control satiety, in particular the role of neuropeptide Y and the satiety hormones peptide YY and pancreatic polypeptide. By understanding how satiety is controlled, this process could be stimulated for potential use as a novel treatment strategy for obesity or anorexia.